GNA15 anticorps (Guanine Nucleotide Binding Protein (G Protein), alpha 15 (Gq Class)) (HRP)

Details for Product anti-GNA15 Antibody No. ABIN1712298, Fournisseur: Connectez-vous pour afficher
Antigène
  • GNA16
  • G[a]15
  • Galpha15
  • guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
  • guanine nucleotide binding protein, alpha 15
  • GNA15
  • Gna15
Reactivité
Humain, Souris, Rat (Rattus)
59
40
27
2
1
1
1
Hôte
Lapin
52
7
Clonalité
Polyclonal
Conjugué
Cet anticorp GNA15 est conjugé à/à la HRP
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
46
15
13
12
5
2
1
1
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human G protein alpha 16
Isotype IgG
Purification Purified by Protein A.
Autre désignation G Protein alpha 16 (GNA15 Antibody Extrait)
Sujet

Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenylyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G alpha subunits have been identified, these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gi class comprises all the known a subunits that are susceptible to pertussis toxin modifications, including Ga i-1, Ga i-2, Ga i-3, Ga o, Ga t1, Ga t2, Ga z and Ga gust (4). Of these, the three Ga i subtypes function to open atrial potassium channels (6). Ga 16 is a member of the Gq subfamily and is expressed specifically in hematopoietic cells (7).

Synonyms: G alpha 15, G alpha 16, G alpha-15, G alpha-16, G-protein subunit alpha-15, G-protein subunit alpha-16, GNA 15, GNA 16, GNA15, GNA15_HUMAN, GNA16, Gq class, Guanine nucleotide binding protein alpha 15, Guanine nucleotide binding protein alpha 15 subunit, Guanine nucleotide-binding protein subunit alpha-15, Guanine nucleotide-binding protein subunit alpha-16.

ID gène 2769
Domaine de recherche Signaling, Receptors
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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