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GNL3L anticorps (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like) (HRP)

Détail du produit anti-GNL3L anticorps No. ABIN1712331, Fournisseur: Connectez-vous pour afficher
Antigène
  • SI:zK13A21.8
  • flj10613
  • flj10613l
  • si:dkey-13a21.8
  • zgc:110536
  • BC020354
  • guanine nucleotide binding protein-like 3 (nucleolar)-like
  • gnl3l
  • GNL3L
  • Gnl3l
Reactivité
Humain, Souris, Rat (Rattus)
56
23
20
7
3
3
3
2
1
Hôte
Lapin
56
Clonalité
Polyclonal
Conjugué
Cet anticorp GNL3L est conjugé à/à la HRP
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
43
22
17
13
7
6
6
5
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human GNL3L
Isotype IgG
Purification Purified by Protein A.
Autre désignation Gnl3l (GNL3L Antibody Extrait)
Sujet

GTPases from the MMR1/HSR1 GTP-binding protein subfamily are circularly rearranged G-motifs that play a critical role in maintaining normal cell growth. Deletion of these genes results in severe growth defects with a marked reduction in mature rRNA species and a concomitant accumulation of the 35S pre-rRNA transcript. Deletion also causes the ribosomal protein Rpl25a to fail exportation from the nucleolus. Deletion of any of the G-domain motifs will result in a null phenotype and nuclear/nucleolar localization that lacks the nucleolar export of preribosomes and is accompanied by a distortion of the nucleolar structure. GNL3L (guanine nucleotide binding protein-like 3 (nucleolar)-like) is a 582 amino acid nuclear protein that belongs to the MMR1/HSR1 GTP-binding protein family. Containing one G (guanine nucleotide-binding) domain, GNL3L is required for normal processing of ribosomal pre-rRNA and for cell proliferation.


Synonyms: GNL3L_HUMAN, FLJ10613, Guanine nucleotide binding protein-like 3 nucleolar-like, novel GTPase, OTTHUMP00000023374.
ID gène 54552
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months