Betacellulin anticorps (BTC) (PE)

Details for Product anti-BTC Antibody No. ABIN1712667, Fournisseur: Connectez-vous pour afficher
Antigène
  • BTC
  • LOC100228121
  • probetacellulin
  • Bcn
  • betacellulin
  • betacellulin-like
  • betacellulin, epidermal growth factor family member
  • BTC
  • LOC100228121
  • Btc
  • LOC100343154
Alternatives
anti-Humain Betacellulin anticorps pour Blocking Antibody
Reactivité
Humain
96
29
5
3
3
Hôte
Lapin
77
24
16
1
1
Clonalité
Polyclonal
Conjugué
Cet anticorp Betacellulin est conjugé à/à la PE
14
5
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
98
37
34
24
13
7
7
7
3
3
2
2
2
1
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human Betacellulin
Isotype IgG
Purification Purified by Protein A.
Autre désignation beta Cellulin (BTC Antibody Extrait)
Sujet

Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, was originally identified as a growth-promoting factor in the conditioned medium of a mouse pancreatic-cell carcinoma (insulinoma) cell line and has since been identified in humans. BTC is synthesized as a large transmembrane precursor molecule that can be cleaved proteolytically to release the soluble form of BTC or function as membrane-anchored growth factors in juxtacrine signaling. BTC, in addition to stimulating homodimers of ErbB-1 and ErbB-4, is capable of binding and activating all possible combinations of heterodimeric ErbB receptors including the oncogenic ErbB-2/ErbB-3 complex. BTC is also expressed in some human malignancies and may have an important role in tumor growth progression.

Subcellular location: Extracellular


Synonyms: Beta cellulin, Beta cellulin precursor, BTC, BTC_HUMAN, OTTHUMP00000160600, OTTHUMP00000219057, Probetacellulin.
ID gène 685
Pathways Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Indications d'application FCM(1:20-100)
Commentaires

Exitation/Emission: 480,565nm/578nm

Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months