Glucocorticoid Receptor anticorps (AA 150-176) (FITC)

N° du produit ABIN180854

L’anticorps anti-Glucocorticoid Receptor Monoclonal Souris est utilisé pour la détection de Glucocorticoid Receptor dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour Glucocorticoid Receptor anticorps (AA 150-176) (FITC) (ABIN180854)

Antigène: Glucocorticoid Receptor (NR3C1) (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Glucocorticoid Receptor est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: 5-00E-004

Détail du produit anti-Glucocorticoid Receptor anticorps (FITC)

Épitope: AA 150-176

Specificité: This antibody recognises a glucocorticoid receptor, located in the cytoplasm of cells and associated with certain heat shock proteins.

Attributs du produit: Synonyms: NR3C1, GR, GRL

Purification: Ion Exchange Chromatography

Immunogène: 26 amino acid peptide corresponding to residues 150-176 on human GCR linked tothyroglobulin

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: neat - 1/10, use 10 μL of the suggested working dilution to label 10^6 cells. Membrane permeabilisation is required for this application.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4, containing, 0.09 % Sodium Azide, 1 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Glucocorticoid Receptor

Antigène: Glucocorticoid Receptor (NR3C1) (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))

Autre désignation: Glucocorticoid Receptor

Sujet: Steroid receptors are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Glucocorticoids are a family of steroids necessary for the regulation of energy metabolism and the immune and inflammatory responses. These compounds exert their effect through their interaction with the glucocoticoid receptor (GR) and that complex's subsequent association with DNA. All normal mammalian tissues examined to date have been shown to contain glucocorticoid receptor.Synonyms: GR, GRL, NR3C1

ID gène: 2908

UniProt: P04150

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Regulation of Carbohydrate Metabolic Process