PSMD4/ASF anticorps (C-Term)

N° du produit ABIN182537

Détail du produit anti-PSMD4/ASF anticorps

Antigène: PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Mouton, Chien, Lapin, Cobaye, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMD4/ASF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: VMQDPEFLQS VLENLPGVDP NNEAIRNAMG SLASQATKDG KKDKKEEDKK

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PSMD4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human PSMD4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 377 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PSMD4/ASF

Antigène: PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))

Autre désignation: PSMD4 (Psmd4 Produits)

Synonymes: anticorps af-1, anticorps mcb1, anticorps pub-r5, anticorps rpn10, anticorps PSMD4, anticorps DDBDRAFT_0202512, anticorps DDBDRAFT_0232981, anticorps DDB_0202512, anticorps DDB_0232981, anticorps AF, anticorps AF-1, anticorps ASF, anticorps MCB1, anticorps Rpn10, anticorps S5A, anticorps pUB-R5, anticorps xrpn10c, anticorps Af1, anticorps Mcb1, anticorps angiocidin, anticorps im:6912672, anticorps psmd4, anticorps wu:fc68c04, anticorps zgc:110247, anticorps proteasome 26S subunit, non-ATPase 4, anticorps 26S proteasome non-ATPase regulatory subunit 4, anticorps 26s proteasome non-atpase regulatory subunit 4 (26s proteasomeregulatory subunit s5a), anticorps proteasome 26S subunit, non-ATPase 4 L homeolog, anticorps proteasome (prosome, macropain) 26S subunit, non-ATPase, 4, anticorps proteasome 26S subunit, non-ATPase 4b, anticorps psmd4, anticorps PSMD4, anticorps LOC100194679, anticorps psmD4, anticorps LOC100283637, anticorps Smp_000740.1, anticorps psmd4.L, anticorps Psmd4, anticorps psmd4b

Sujet: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD4 encodes one of the non-ATPase subunits of the 19S regulator lid.
Alias Symbols: AF, ASF, S5A, AF-1, MCB1, Rpn10, pUB-R5
Protein Interaction Partner: UBC, cdc20, XPC, SPRTN, PSMD14, MDM2, PSMC2, PSMA1, ADRM1, UBQLN1, TXNL1, PSMD3, PSMD2, PSMD1, PSMC6, PSMC4, PSMC1, UCHL5, RPS12, PSMD8, UBQLN4, VCP, GJA1, DIO2, SCHIP1, FBXO6, PARK2, UL76, FBXO25, LOC100044627, Gm4705, LOC677113, Rps6-ps4, Rpl34-ps1, Rpl
Protein Size: 377

Poids moléculaire: 41 kDa

ID gène: 5710

NCBI Accession: NM_002810, NP_002801

UniProt: P55036

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway