POU1F1 anticorps

N° du produit ABIN2457941

Détail du produit anti-POU1F1 anticorps

Antigène: POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

Reactivité: Humain, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POU1F1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human POU1F1.

Information d'application

Indications d'application: POU1F1 antibody can be used for detection of POU1F1 by ELISA at 1:312500. POU1F1 antibody can be used for detection of POU1F1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store POU1F1 antibody at -20 °C.

Détails sur POU1F1

Antigène: POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

Autre désignation: POU1F1 (POU1F1 Produits)

Synonymes: anticorps CPHD1, anticorps GHF-1, anticorps PIT1, anticorps POU1F1a, anticorps Pit-1, anticorps Hmp1, anticorps Pit1, anticorps Pit1-rs1, anticorps dw, anticorps dwarf, anticorps GHF1, anticorps GHF1A, anticorps PIT1Z, anticorps PIT-1, anticorps Pit-1*, anticorps pit1, anticorps pit-1, anticorps POU class 1 homeobox 1, anticorps POU domain, class 1, transcription factor 1, anticorps POU1F1, anticorps Pou1f1, anticorps pou1f1

Sujet: PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP. This gene encodes a member of the POU family of transcription factors that regulate mammalian development. The protein regulates expression of several genes involved in pituitary development and hormone expression. Mutations in this genes result in combined pituitary hormone deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 33 kDa

ID gène: 5449

NCBI Accession: NP_000297

UniProt: P28069

Pathways: Regulation of Carbohydrate Metabolic Process