POU1F1 anticorps (C-Term)

N° du produit ABIN2777285

Cet anticorps Lapin Polyclonal détecte spécifiquement POU1F1 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Chien, Souris, Rat, Boeuf (Vache), Chévre, Cheval, Lapin, Mouton, Cobaye et Poisson zèbre (Danio rerio).Il a été cité dans 1 publication.

Aperçu rapide pour POU1F1 anticorps (C-Term) (ABIN2777285)

Antigène: POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

Reactivité: Humain, Chien, Souris, Rat, Boeuf (Vache), Chévre, Cheval, Lapin, Mouton, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POU1F1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-POU1F1 anticorps

Épitope: C-Term

Fonction: POU1F1 Antibody - C-terminal region

Séquence: QEIMRMAEEL NLEKEVVRVW FCNRRQREKR VKTSLNQSLF SISKEHLECR

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against POU1F1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human POU1F1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108742

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-POU1F1 (ABIN2777285)

Tennant, Gottlieb: "HIF prolyl hydroxylase-3 mediates alpha-ketoglutarate-induced apoptosis and tumor suppression." dans: Journal of molecular medicine (Berlin, Germany), Vol. 88, Issue 8, pp. 839-49, (2010) (PubMed).

Détails sur POU1F1

Antigène: POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

Autre désignation: POU1F1

Sujet:

Background Information: PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP.

Gene Name: POU class 1 homeobox 1

Alternative Symbols: PIT1, CPHD1, GHF-1, Pit-1, POU1F1a

Protein Name: Pituitary-specific positive transcription factor 1

Poids moléculaire: 33kDa

ID gène: 5449

NCBI Accession: NP_000297

UniProt: P28069

Pathways: Regulation of Carbohydrate Metabolic Process