OCT4 anticorps
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- Antigène Voir toutes OCT4 (POU5F1) Anticorps
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp OCT4 est non-conjugé
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- OCT-4 immunostaining has been shown to be a sensitive and specific marker for seminomatous / (dys)germinomatous tumours and in embryonal carcinoma variants of non-seminomatous GCTs, whether in primary gonadal or extragonadal sites or in metastatic lesions.
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Attributs du produit
- Synonyms: POU5F1, OCT3, OCT4, OTF3, POU domain, class 5, transcription factor 1, Octamer-bindingtranscription factor 3, Oct-3, Oct-4
- Purification
- Purified
- Immunogène
- BALB/C mice injected with synthetic peptide of human OCT-4 origin.
- Clone
- NRG1-1
- Isotype
- IgG2b
- Top Product
- Discover our top product POU5F1 Anticorps primaire
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- Indications d'application
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Suitable for Immunohistochemistry on Formalin fixed paraffin embedded tissue sections: 1/25-1/100 in an ABC method. Positive Control: Seminoma. Cellular Localization: Nuclear.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Protocole
- Staining ProtocolWe suggest an incubation period of 30 minutes at room temperature. However, dependingupon the fixation conditions and the staining system employed, optimal incubation should be determined by the end user. Formalin fixed paraffin embedded tissue sections require
- Restrictions
- For Research Use only
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- Format
- Liquid
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- Antigène
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
- Autre désignation
- OCT3/4 (POU5F1 Produits)
- Synonymes
- anticorps OCT3, anticorps OCT4, anticorps OTF-3, anticorps OTF3, anticorps OTF4, anticorps Oct-3, anticorps Oct-4, anticorps POU5F1, anticorps gp9, anticorps gp-9, anticorps oct4, anticorps pou2, anticorps POU-2, anticorps cb197, anticorps spg/pou2, anticorps chunp6868, anticorps wu:fd18d06, anticorps NF-A3, anticorps Oct-3/4, anticorps Oct3, anticorps Oct3/4, anticorps Oct4, anticorps Otf-3, anticorps Otf-4, anticorps Otf3, anticorps Otf3-rs7, anticorps Otf3g, anticorps Otf4, anticorps POU class 5 homeobox 1, anticorps POU domain, class 5, transcription factor 3, anticorps POU domain, class 5, transcription factor 1, anticorps POU5F1, anticorps pou5f3, anticorps Pou5f1
- Sujet
- OCT-4 (also known as POU5F1), a transcription factor that has been recognized as fundamental in the maintenance of pluripotency in embryonic stem cells and primordial germ cells, has been proposed as a useful marker for Germ Cell Tumors (GCTs) that exhibit features of pluripotentiality, specifically seminoma / dysgerminoma / germinoma and embryonal carcinoma.Synonyms: OCT3, OCT4, OTF3, Oct-3, Oct-4, Octamer-binding transcription factor 3, POU domain, POU5F1, class 5, transcription factor 1
- ID gène
- 5460
- UniProt
- Q01860
- Pathways
- Stem Cell Maintenance
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