HDAC9 anticorps (Middle Region)
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- Antigène Voir toutes HDAC9 Anticorps
- HDAC9 (Histone Deacetylase 9 (HDAC9))
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Épitope
- Middle Region
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Reactivité
- Humain, Rat, Souris, Chien, Cobaye, Mouton, Boeuf (Vache), Cheval, Lapin, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HDAC9 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GQVGAVKVKE EPVDSDEDAQ IQEMESGEQA AFMQQVIGKD LAPGFVIKVI
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against HDAC9. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human HDAC9
- Top Product
- Discover our top product HDAC9 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 590 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Epigenetic regulation of established human type 1 versus type 2 cytokine responses." dans: The Journal of allergy and clinical immunology, Vol. 121, Issue 1, pp. 57-63.e3, (2008) (PubMed).
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Epigenetic regulation of established human type 1 versus type 2 cytokine responses." dans: The Journal of allergy and clinical immunology, Vol. 121, Issue 1, pp. 57-63.e3, (2008) (PubMed).
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- Antigène
- HDAC9 (Histone Deacetylase 9 (HDAC9))
- Autre désignation
- HDAC9 (HDAC9 Produits)
- Synonymes
- anticorps HD7, anticorps HD7b, anticorps HD9, anticorps HDAC, anticorps HDAC7, anticorps HDAC7B, anticorps HDAC9B, anticorps HDAC9FL, anticorps HDRP, anticorps MITR, anticorps AV022454, anticorps D030072B18Rik, anticorps HD7B, anticorps Hdac7b, anticorps Mitr, anticorps mKIAA0744, anticorps hdac9, anticorps zgc:73392, anticorps TWIST, anticorps HDAC9, anticorps DKFZp459E171, anticorps HDA09, anticorps HISTONE DEACETYLASE, anticorps histone deacetylase 9, anticorps RGD1310748, anticorps RGD1563092, anticorps hdac9-A, anticorps histone deacetylase 9, anticorps histone deacetylase 9b, anticorps histone deacetylase 9 S homeolog, anticorps HDAC9, anticorps Hdac9, anticorps hdac9b, anticorps HDA9, anticorps hdac9.S
- Sujet
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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC9 has sequence homology to members of the histone deacetylase family. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. HDAC9 may play a role in hematopoiesis. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.
Alias Symbols: DKFZp779K1053, HD7, HDAC, HDAC7, HDAC7B, HDAC9B, HDAC9FL, HDRP, KIAA0744, MITR, HD9, HD7b
Protein Interaction Partner: NOP2, MKI67, EIF6, RCC1, ADAR, TOP1, TMPO, FIP1L1, CCAR2, TPX2, RBM14, ZC3H11A, HDAC9, NUP93, SMC3, H1FX, TPR, HINT1, CTBP1, BCL6, Zfp521, TRIM29, TP53, MAML1, SMARCA4, PARP1, CEBPB, H3F3A, RL2, CAMK1, YWHAE, HDAC1, SFN, MEF2B, ANKRA2, RFXANK, PKD1, SYK,
Protein Size: 590 - Poids moléculaire
- 66 kDa
- ID gène
- 9734
- NCBI Accession
- NM_014707, NP_055522
- UniProt
- A7E2F3
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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