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COQ8A anticorps (N-Term)

COQ8A Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2783345
  • Antigène Voir toutes COQ8A Anticorps
    COQ8A (Coenzyme Q8A (COQ8A))
    Épitope
    • 15
    • 8
    • 8
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 52
    • 31
    • 30
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)
    Hôte
    • 53
    • 13
    Lapin
    Clonalité
    • 53
    • 13
    Polyclonal
    Conjugué
    • 26
    • 6
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp COQ8A est non-conjugé
    Application
    • 57
    • 32
    • 13
    • 13
    • 10
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    FANPRDSFSA MGFQRRFFHQ DQSPVGGLTA EDIEKARQAK ARPENKQHKQ
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 90%
    Attributs du produit
    This is a rabbit polyclonal antibody against CABC1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human CABC1
    Top Product
    Discover our top product COQ8A Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 647 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lagier-Tourenne, Tazir, López, Quinzii, Assoum, Drouot, Busso, Makri, Ali-Pacha, Benhassine, Anheim, Lynch, Thibault, Plewniak, Bianchetti, Tranchant, Poch, DiMauro, Mandel, Barros, Hirano, Koenig: "ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency." dans: American journal of human genetics, Vol. 82, Issue 3, pp. 661-72, (2008) (PubMed).

  • Antigène
    COQ8A (Coenzyme Q8A (COQ8A))
    Autre désignation
    CABC1 (COQ8A Produits)
    Synonymes
    anticorps ARCA2, anticorps CABC1, anticorps COQ10D4, anticorps COQ8, anticorps SCAR9, anticorps 4632432J16Rik, anticorps AI462003, anticorps Cabc1, anticorps mKIAA0451, anticorps cabc1, anticorps Adck3, anticorps adck4, anticorps si:dkey-114g7.2, anticorps coenzyme Q8A, anticorps aarF domain containing kinase 3, anticorps coenzyme Q8B, anticorps COQ8A, anticorps Coq8a, anticorps coq8a, anticorps ADCK3, anticorps coq8b
    Sujet
    CABC1 is a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis.This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found, however, their full-length nature has not been determined.
    Alias Symbols: ADCK3, COQ8, MGC4849, ARCA2, CABC1, SCAR9
    Protein Interaction Partner: TMEM239, REEP6, TMEM159, AGTRAP, TFIP11, RABAC1, VCP, UBC, IRAK2, IRAK1, ICT1, COQ8,
    Protein Size: 647
    Poids moléculaire
    72 kDa
    ID gène
    56997
    NCBI Accession
    NM_020247, NP_064632
    UniProt
    Q8NI60
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