GAD anticorps (N-Term)
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- Antigène Voir toutes GAD (GAD1) Anticorps
- GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GAD est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MASSTPSSSA TSSNAGADPN TTNLRPTTYD TWCGVAHGCT RKLGLKICGF
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against GAD1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human GAD1
- Top Product
- Discover our top product GAD1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 594 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
- Autre désignation
- GAD1 (GAD1 Produits)
- Synonymes
- anticorps CPSQ1, anticorps GAD, anticorps SCP, anticorps GAD-67, anticorps cpsq1, anticorps gad1, anticorps gad1-A, anticorps gad67, anticorps GAD67, anticorps GAD1, anticorps GLUTAMATE DECARBOXYLASE, anticorps GLUTAMATE DECARBOXYLASE 1, anticorps MKP11.30, anticorps MKP11_30, anticorps glutamate decarboxylase, anticorps EP10, anticorps GAD25, anticorps GAD44, anticorps Gad-1, anticorps Gad67, anticorps glutamate decarboxylase 1, anticorps glutamate decarboxylase 1 L homeolog, anticorps glutamate decarboxylase, anticorps glutamate decarboxylase 1b, anticorps GAD1, anticorps gad1.1.L, anticorps GAD, anticorps Gad1, anticorps gad1b
- Sujet
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This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
Alias Symbols: FLJ45882, GAD, SCP, CPSQ1
Protein Interaction Partner: CMTM5, AGTRAP, HAAO, STK3, GAD2, PPP2CA, PRKCE, PPP2CB, PRKACA,
Protein Size: 594 - Poids moléculaire
- 67 kDa
- ID gène
- 2571
- NCBI Accession
- NM_000817, NP_000808
- UniProt
- Q99259
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