NKIRAS1 anticorps (N-Term)
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- Antigène Voir toutes NKIRAS1 Anticorps
- NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Chévre, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NKIRAS1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- CETMEDVYMA SVETDRGVKE QLHLYDTRGL QEGVELPKHY FSFADGFVLV
- Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against NKIRAS1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human NKIRAS1
- Top Product
- Discover our top product NKIRAS1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 192 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
- Autre désignation
- NKIRAS1 (NKIRAS1 Produits)
- Synonymes
- anticorps NKIRAS1, anticorps KBRAS1, anticorps kappaB-Ras1, anticorps zgc:92823, anticorps kbras1, anticorps 2400004O09Rik, anticorps NFKB inhibitor interacting Ras like 1, anticorps NFKB inhibitor interacting Ras-like 1, anticorps NFKB inhibitor interacting Ras-like 1 S homeolog, anticorps NFKB inhibitor interacting Ras-like protein 1, anticorps NKIRAS1, anticorps nkiras1, anticorps nkiras1.S, anticorps Nkiras1
- Sujet
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NKIRAS1 is an atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. NKIRAS1 may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
Alias Symbols: KBRAS1, kappaB-Ras1
Protein Interaction Partner: XRCC2, UBC, APP, NFKBIB, SMURF2, BMPR1B, TGFBR1, NFKBIA, ACVR1,
Protein Size: 192 - Poids moléculaire
- 22 kDa
- ID gène
- 28512
- NCBI Accession
- NM_020345, NP_065078
- UniProt
- Q9NYS0
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