CD33 anticorps (N-Term)
-
- Antigène Voir toutes CD33 Anticorps
- CD33
-
Épitope
- N-Term
-
Reactivité
- Humain, Boeuf (Vache), Cheval
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp CD33 est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- HPIPYYDKNS PVHGYWFREG AIISRDSPVA TNKLDQEVQE ETQGRFRLLG
- Homologie
- Cow: 79%, Horse: 79%, Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against CD33. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product CD33 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 364 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- CD33
- Autre désignation
- CD33 (CD33 Produits)
- Synonymes
- anticorps SIGLEC-3, anticorps SIGLEC3, anticorps p67, anticorps Siglec-3, anticorps gp67, anticorps CD33 molecule, anticorps CD33 antigen, anticorps CD33, anticorps Cd33
- Sujet
-
CD33 is a putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. CD33 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, CD33 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33 induces apoptosis in acute myeloid leukemia (in vitro).
Alias Symbols: FLJ00391, SIGLEC-3, SIGLEC3, p67
Protein Interaction Partner: KRT40, KRT31, HERC3, UBC, CBL, SRC, PTPN6, PTPN11,
Protein Size: 364 - Poids moléculaire
- 38 kDa
- ID gène
- 945
- NCBI Accession
- NM_001772, NP_001763
- UniProt
- P20138
-