MALT1 anticorps (AA 43-57)

N° du produit ABIN298719

Cet anticorps anti-MALT1 Polyclonal Lapin (ABIN298719) détecte spécifiquement MALT1 dans WB, IHC et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MALT1 anticorps (AA 43-57) (ABIN298719)

Antigène: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MALT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MALT1 anticorps

Épitope: AA 43-57

Specificité: A synthetic peptide corresponding to amino acids 43-57 (ELLDQAPEGRGWRRL) of human MALT1 (GenBank No. NP_776216.1) was used as immunogen. The immunogen sequence is 100 % conserved between Malt1 isoforms a and b.

Homologie: Percent identity by BLAST analysis: Human (100%) Monkey (93%) Gorilla, Gibbon, Elephant (87%) Marmoset, Bovine, Bat (80%).

Purification: Protein G purified

Immunogène: A synthetic peptide corresponding to amino acids 43-57 (ELLDQAPEGRGWRRL) of human MALT1 (GenBank No. NP_776216.1). The immunogen sequence is 100% conserved between Malt1 isoforms a and b. Percent identity by BLAST analysis: Human (100%), Monkey (93%), Chimpanzee, Gorilla, Orangutan, Gibbon, Elephant (87%), Galago, Marmoset, Bovine, Cat (80%), Mouse, Rat (73%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Information d'application

Indications d'application: Approved: IHC, IHC-P (10 μg/mL), WB (0.5 - 2 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.2 % gelatin, 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: avoid freeze thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Détails sur MALT1

Antigène: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Autre désignation: MALT1

Sujet: Name/Gene ID: MALT1
Subfamily: Cysteine C14
Family: Protease

Synonyms: MALT1, Caspase-like protein, MLT, MLT1, Paracaspase, MALT associated translocation

ID gène: 10892

NCBI Accession: NP_776216

UniProt: Q9UDY8

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins