TAP1 anticorps (C-Term)

N° du produit ABIN305531

L’anticorps anti-TAP1 Polyclonal Lapin est utilisé pour la détection de TAP1 dans des échantillons de Humain. Il a été validé pour WB, ELISA, IP et FACS.

Aperçu rapide pour TAP1 anticorps (C-Term) (ABIN305531)

Antigène: TAP1 (Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS)

Détail du produit anti-TAP1 anticorps

Épitope: C-Term

Specificité: Detects an epitope within the C-terminal region of human TAP1, also known as transporter associated with antigen processing 1. TAP1 is an 81kD membrane-associated protein which is a member of the ATP-binding cassette (ABC) transporter superfamily and together with the homologous subunit TAP2 forms the functional TAP complex. TAP1 is involved in the transport of antigenic peptides from the cytosol into the endoplasmic reticulum, where they associate with major histocompatibility complex (MHC) class I molecules. These complexes are presented at the cell surface to T-lymphocytes, which identify and remove infected or malignantly transformed cells. AHP1248 does not cross react with TAP2.

Purification: Purified IgG

Immunogène: TAP1 peptide corresponding to the C-terminal of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH). ( C-TERMINAL ).

Isotype: IgG

Information d'application

Indications d'application: Approved: ELISA (1:10000), Flo, IP, WB (1:1000)

Usage: Western Blot: LS-C42564 detects a band of approximately 72kD.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.01 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: avoid freeze thaw cycles. Store undiluted.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.

Détails sur TAP1

Antigène: TAP1 (Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1))

Autre désignation: ABCB2 / TAP1

Sujet: Name/Gene ID: TAP1
Subfamily: ATP-binding cassette - ABCB/MDR
Family: Transporter

Synonyms: TAP1, ABC17, ABCB2, APT1, D6S114E, ABC transporter, MHC 1, Ham1, Peptide transporter TAP1, PSF1, TAP1N, MTP1, Peptide transporter PSF1, PSF-1, Peptide supply factor 1, RING4, Y3

ID gène: 6890

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response