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PPP2CA anticorps (N-Term)

PPP2CA Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN319372
  • Antigène Voir toutes PPP2CA Anticorps
    PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))
    Épitope
    • 16
    • 14
    • 13
    • 8
    • 7
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 68
    • 57
    • 47
    • 13
    • 10
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 76
    • 8
    • 4
    • 2
    • 1
    Lapin
    Clonalité
    • 76
    • 15
    Polyclonal
    Conjugué
    • 57
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PPP2CA est non-conjugé
    Application
    • 76
    • 30
    • 19
    • 17
    • 15
    • 14
    • 13
    • 13
    • 13
    • 5
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Specificité
    PP2A-alpha antibody detects endogenous levels of total PP2A-alpha protein.
    Purification
    Immunoaffinity Chromatography.
    Immunogène
    The antiserum was produced against a synthesized peptide Corresponding to the amino terminal sequence from human PP2A-alpha protein (''KQLSESQVKSL'').
    Top Product
    Discover our top product PPP2CA Anticorps primaire
  • Indications d'application
    Western Blot (1/500-1/1000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store the antibody (in aliquots) at-20 °C.
  • Antigène
    PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))
    Autre désignation
    PPP2CA (PPP2CA Produits)
    Synonymes
    anticorps PP2Ac, anticorps PP2CA, anticorps PP2Calpha, anticorps RP-C, anticorps PP2A, anticorps R75353, anticorps Pp2a1, anticorps pp2ac, anticorps zgc:110641, anticorps protein phosphatase 2 catalytic subunit alpha, anticorps protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform, anticorps protein phosphatase 2, catalytic subunit, alpha isozyme, anticorps protein phosphatase 2 catalytic subunit alpha L homeolog, anticorps protein phosphatase 2, catalytic subunit, beta isozyme, anticorps serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, anticorps PPP2CA, anticorps Ppp2ca, anticorps ppp2ca.L, anticorps ppp2cb, anticorps LOC471633, anticorps ppp2ca
    Sujet
    Protein phosphatase 2A (PP2A) is the most abundant phosphatase specific for serine and threonine phosphorylation in mammalian cells. Dephosphorylation of substrates targeted by PP2A plays a vital role in a large variety of cellular processes including signal transduction, regulation of the cell cycle, gene expression and development. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit alpha serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory beta subunit.Synonyms: PP2A-alpha, Protein Phospatase 2A, Replication protein C, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
    ID gène
    5515
    NCBI Accession
    NP_002706
    UniProt
    P67775
    Pathways
    Signalisation PI3K-Akt, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades
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