NCR1 anticorps
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- Antigène Voir toutes NCR1 Anticorps
- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
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Reactivité
- Boeuf (Vache)
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp NCR1 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
- Specificité
- This Low Endotoxin antibody is specific for Bovine CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1. Clone AKS1 is reported to activate lysis of FcgammaR-expressing cell line P815, by IL-2 activated NKp46+ cells (2).
- Purification
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- niveau d'endotoxine
- Low Endotoxin
- Immunogène
- Fusion protein consisting of the extracellular region of Bovine CD335. Remarks: Spleen cells from immunised Balb/c mice were fused with cells of the NS-0 myeloma cell line.
- Clone
- AKS1
- Isotype
- IgG1
- Top Product
- Discover our top product NCR1 Anticorps primaire
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- Indications d'application
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Flow Cytometry: Use 10 μL of 1/5-1/200 diluted antibody to label 106 cells in 100 μL. Western Blot. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: < 0.01EU/ug. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.4 containing no preservatives.
- Agent conservateur
- Without preservative
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
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- Antigène
- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
- Autre désignation
- CD335 / NKp46 (NCR1 Produits)
- Synonymes
- anticorps CD335, anticorps LY94, anticorps NK-p46, anticorps NKP46, anticorps Ly94, anticorps NKp46, anticorps KILR-1, anticorps Nk-p46, anticorps Nkp46, anticorps natural cytotoxicity triggering receptor 1, anticorps NCR1, anticorps Ncr1
- Sujet
- CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor. CD335 is expressed by human natural killer cells (4). The bovine homologue is expressed on bovine NK cells (2) and no expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes.Synonyms: LY94, NCR1, NK cell-activating receptor, NKp46, Natural cytotoxicity triggering receptor, Natural killer cell p46-related protei
- ID gène
- 369024
- NCBI Accession
- NP_899209
- UniProt
- Q863H2
- Pathways
- Regulation of Leukocyte Mediated Immunity
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