SV2A anticorps (Internal Region)
-
- Antigène Voir toutes SV2A Anticorps
- SV2A (Synaptic Vesicle Glycoprotein 2A (SV2A))
-
Épitope
- Internal Region
-
Reactivité
- Humain, Rat, Souris, Chien
-
Hôte
- Chèvre
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp SV2A est non-conjugé
-
Application
- Western Blotting (WB)
- Specificité
- This antibody recognizes SV2A.
- Réactivité croisée (Details)
-
Species reactivity (expected):Mouse, Human, Canine.
Species reactivity (tested):Rat. - Purification
- Affinity chromatography
- Immunogène
- Peptide with sequence C-TVELYPSDKRTTA, from the internal region of the protein sequence
- Top Product
- Discover our top product SV2A Anticorps primaire
-
-
- Indications d'application
-
Peptide ELISA: 1/64000. Western Blot: 0.3-1 μg/mL. Approx 80 kDa band observed in rat brain lysates (calculatedMW of 82.0 kDa according to NP_476558.1 (rat)). An additonal band of unknown identitywas also consistently observed at 20 kDa. This band was successfully blocked byincubation with the immunising peptide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, 0.02 % Sodium Azide, pH 7.3 with 0.5 % BSA
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Antigène
- SV2A (Synaptic Vesicle Glycoprotein 2A (SV2A))
- Autre désignation
- SV2A (SV2A Produits)
- Synonymes
- anticorps AI746429, anticorps mKIAA0736, anticorps Sv2, anticorps SV2, anticorps synaptic vesicle glycoprotein 2A, anticorps synaptic vesicle glycoprotein 2 a, anticorps synaptic vesicle glycoprotein 2a, anticorps SV2A, anticorps CpipJ_CPIJ017596, anticorps sv2a, anticorps Sv2a
- Sujet
- SV2s (Synaptic Vesicle protein 2) are integral membrane glycoproteins present in all synaptic vesicles. They have 12 transmembrane domains predicted by sequence analysis. There are three characterized isoforms, SV2A, SV2B and SV2C. SV2A is expressed ubiquitously throughout the brain. SV2B has a more restricted distribution with varying degrees of coexpression with SV2A. SV2C is more closely related to SV2A but shows a very restricted expression pattern. The highest expression levels were observed in phylogenetically old brain areas like pallidum, the midbrain and the olfactory bulb. SV2A is probably involved in the maintenance of a pool of synaptic vesicles competent for calcium-stimulated exocytosis. SV2A is a highly glycosylated synaptic vesicle protein with homology to transmembrane transporters.Synonyms: KIAA0736, Synaptic vesicle glycoprotein 2A
- ID gène
- 9900
- NCBI Accession
- NP_055664
- UniProt
- Q7L0J3
-