LGR5 anticorps (AA 443-473)

N° du produit ABIN389219

Détail du produit anti-LGR5 anticorps

Antigène: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Épitope: AA 443-473

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LGR5 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This LGR5 (GPR49) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 443-473 amino acids from the Central region of human LGR5 (GPR49).

Clone: RB14555

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC: 1:100. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-LGR5 (ABIN389219)

Judah, Rudkouskaya, Wilson, Carter, Dagnino: "Multiple roles of integrin-linked kinase in epidermal development, maturation and pigmentation revealed by molecular profiling." dans: PLoS ONE, Vol. 7, Issue 5, pp. e36704, (2012) (PubMed).

Walker, Zhang, Odorizzi, Burgess: "LGR5 is a negative regulator of tumourigenicity, antagonizes Wnt signalling and regulates cell adhesion in colorectal cancer cell lines." dans: PLoS ONE, Vol. 6, Issue 7, pp. e22733, (2011) (PubMed).

Détails sur LGR5

Antigène: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Autre désignation: LGR5 (GPR49) (LGR5 Produits)

Synonymes: anticorps lgr5-a, anticorps lgr5a, anticorps FEX, anticorps Gpr49, anticorps GPR49, anticorps GPR67, anticorps GRP49, anticorps HG38, anticorps leucine-rich repeat containing G protein-coupled receptor 5 L homeolog, anticorps leucine rich repeat containing G protein coupled receptor 5, anticorps leucine rich repeat containing G protein-coupled receptor 5, anticorps lgr5.L, anticorps Lgr5, anticorps LGR5

Sujet: LGR5/GPR49 is an orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues.

Poids moléculaire: 99998

ID gène: 8549

NCBI Accession: NP_001264155, NP_003658

UniProt: O75473

Pathways: Signalisation WNT