ACVR2A anticorps (AA 421-513)

N° du produit ABIN4886422

Détail du produit anti-ACVR2A anticorps

Antigène: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Épitope: AA 421-513

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACVR2A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Activin receptor type-2A(ACVR2A) detection. Tested with WB, IHC-P in Human,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Activin receptor type-2A(ACVR2A) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: activin A receptor type 2A
Protein Name: Activin receptor type-2A

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human ACVR2A recombinant protein (Position: Q421-L513). Human ACVR2A shares 100% and 98.9% amino acid (aa) sequence identity with mouse and rat ACVR2A, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur ACVR2A

Antigène: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Autre désignation: ACVR2A (ACVR2A Produits)

Synonymes: anticorps ACVR2, anticorps ACVR2A, anticorps XSTK9, anticorps actrii, anticorps acvr2, anticorps ACTRII, anticorps Acvr2, anticorps rActR-II, anticorps actr2a, anticorps acvr2a, anticorps wu:fa02e10, anticorps ActrIIa, anticorps TactrII, anticorps activin A receptor type 2A, anticorps activin A receptor type 2A L homeolog, anticorps activin A receptor type 2Aa, anticorps activin receptor IIA, anticorps ACVR2A, anticorps acvr2a, anticorps Acvr2a, anticorps acvr2a.L, anticorps acvr2aa

Sujet: Activin receptor type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.

Synonyms: ACTR 2 | ACTR2 | ACTR IIA | ACTRIIA | ACTR-IIA | ACTRII | Acvr 2 | Acvr2 | Acvr 2A | Acvr2A | P27037

ID gène: 92

UniProt: P27037