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Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) (Middle Region) anticorps

Détails pour le produit réf. ABIN501659, Fournisseur: Connectez-vous pour afficher Nouveau
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Antigène
Synonymes
ZFP36, ttp, C3H-1, g0s24, gos24, tis11, nup475, rnf162a, 2610110L04Rik, AA792898, AU022812, ZNF230, c3h-1, G0S24, GOS24, NUP475, RNF162A, TIS11, TTP, zfp-36, Tis11, Gos24, Nup475, TIS11D, TISII, Ttp,  ... voir plus
ZFP36, ttp, C3H-1, g0s24, gos24, tis11, nup475, rnf162a, 2610110L04Rik, AA792898, AU022812, ZNF230, c3h-1, G0S24, GOS24, NUP475, RNF162A, TIS11, TTP, zfp-36, Tis11, Gos24, Nup475, TIS11D, TISII, Ttp, Zfp-36 show less
Épitope
Middle Region
(14), (11), (7), (6), (3), (2), (2), (1), (1)
Reactivité
Boeuf (Vache), Chien, Humain, Souris, Porc, Rat (Rattus)
(76), (9), (6), (3), (2), (2), (2), (2), (2), (1)
Hôte
Lapin
(48), (28)
Clonalité
Polyclonal
Conjugué
Inconjugué
(2), (2), (2), (2), (2), (2)
Application
Immunohistochimie (IHC), Transfer Western (WB)
(68), (27), (25), (15), (7), (6), (3), (1), (1)
Pubmed 1 référence disponible
Fournisseur Connectez-vous pour afficher Nouveau
Numéro du produit fournisseur Connectez-vous pour afficher Nouveau
Quantité 50 μg
Options
Destination France ( )
Disponibilité Envoi sous 6 à 8 jours ouvrables
Immunogène Synthetic peptide directed towards the middle region of human ZFP36
Blocking Peptide Blocking peptide for this product available: ABIN986434
Séquence PSCRRATPIS VWGPLGGLVR TPSVQSLGSD PDEYASSGSS LGGSDSPVFE
Homologie Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Pig : 100 %, Rabbit : 100 %, Sheep : 100 %, Mouse : 90 %, Rat : 90 %
Attributs du produit This is a rabbit polyclonal antibody against ZFP36. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Autre désignation ZFP36 (ZFP36 Antibody Extrait)
Sujet ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors. Knockdown of ZFP36 increased both cognate macrophage gene mRNAs and inflammatory tumor necrosis factor protein release. Overexpression of ZFP36 resulted in decreased levels of the same genes supporting its role in regulating macrophage gene expression. Multiple phosphorylation sites in ZFP36 in mammalian cells were reported. ZFP36 can be phosphorylated by JNK as well as by the other members of the greater MAP kinase family. Gene expression profiling predicts clinical outcome of prostate cancer. Inappropriate ZFP36 production may be one factor that contributes to higher rheumatoid arthritis disease activity.
Poids moléculaire 34 kDa
ID gène 7538
NCBI Accession NP_003398, NM_003407
UniProt P26651
Indications d'application Optimal working dilutions should be determined experimentally by the investigator.
Commentaires

Antigen size: 326 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Conseil sur la manipulation Avoid repeated freeze-thaw cycles.
Stock -20 °C
Stockage commentaire For longer periods of storage, store at -20 °C
Supplier Images
Immunohistochimie (IHC) image for anti-Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) (Middle Region) anticorps (ABIN501659) IHC Information: Paraffin embedded small intestine, submucosal plexus tissue, ...
Reference: Background Emmons, Townley-Tilson, Deleault et al.: "Identification of TTP mRNA targets in human dendritic cells reveals TTP as a critical regulator of dendritic cell maturation." dans: RNA (New York, N.Y.), Vol. 14, Issue 5, pp. 888-902, 2008 (PubMed).

N° du produit ABIN501659
358,51 €
Plus frais de livraison 40,00 € et TVA

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