Aurora Kinase C anticorps (N-Term)

N° du produit ABIN615936

Détail du produit anti-Aurora Kinase C anticorps

Antigène: Aurora Kinase C (AURKC)

Épitope: N-Term

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Aurora Kinase C est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: PRAVVQLGKA QP-C

Specificité: This antibody is expected to recognize isoform 1 (NP_001015878.1) only.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the N Terminus of the protein sequence according to NP_001015878.1. Genename: AURKC

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Aurora Kinase C

Antigène: Aurora Kinase C (AURKC)

Autre désignation: Aurora Kinase C (AURKC Produits)

Synonymes: anticorps AURKC, anticorps AIE2, anticorps AIK3, anticorps ARK3, anticorps AurC, anticorps SPGF5, anticorps STK13, anticorps aurora-C, anticorps AIE1, anticorps ARK-3, anticorps IAK3, anticorps Stk13, anticorps aurora kinase C, anticorps AURKC, anticorps Aurkc

Sujet: Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.Synonyms: AIE2, AIK3, AURKC, Aurora-C, Aurora/Ipl1-related kinase 3, Aurora/Ipl1/Eg2 protein 2, STK13, Serine/threonine-protein kinase 13

ID gène: 6795

NCBI Accession: NP_001015878

UniProt: Q9UQB9

Pathways: Cycle Cellulaire, Maintenance of Protein Location