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Human Monoclonal CXCL1 Primary Antibody pour CyTOF, ELISA (Capture) - ABIN4900740
Meen, Øynebråten, Reine, Duelli, Svennevig, Pejler, Jenssen, Kolset: Serglycin is a major proteoglycan in polarized human endothelial cells and is implicated in the secretion of the chemokine GROalpha/CXCL1. dans The Journal of biological chemistry 2011
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Human Monoclonal CXCL1 Primary Antibody pour CyTOF, ELISA (Capture) - ABIN4900741
Gelderblom, Weymar, Bernreuther, Velden, Arunachalam, Steinbach, Orthey, Arumugam, Leypoldt, Simova, Thom, Friese, Prinz, Hölscher, Glatzel, Korn, Gerloff, Tolosa, Magnus: Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke. dans Blood 2012
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Human Polyclonal CXCL1 Primary Antibody pour WB - ABIN3044150
Xu, Zhu, Zhang, Tian, Zhang, Wu, Gao: NF?B-mediated CXCL1 production in spinal cord astrocytes contributes to the maintenance of bone cancer pain in mice. dans Journal of neuroinflammation 2014
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Human Polyclonal CXCL1 Primary Antibody pour IHC, IHC (p) - ABIN4316223
Yeh, Shun, Kuo, Jung, Hsieh, Chiu, Chen, Hsu, Yang, Chia: Activated human valvular interstitial cells sustain interleukin-17 production to recruit neutrophils in infective endocarditis. dans Infection and immunity 2015
Mouse (Murine) Polyclonal CXCL1 Primary Antibody pour IF (p), IHC (p) - ABIN2173443
Ito, Katano, Kawai, Yagoto, Takahashi, Ka, Ogura, Takahashi, Ito: A Novel Xenogeneic Graft-Versus-Host Disease Model for Investigating the Pathological Role of Human CD4(+) or CD8(+) T Cells Using Immunodeficient NOG Mice. dans American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2016
Rat (Rattus) Polyclonal CXCL1 Primary Antibody pour Func, ELISA - ABIN2473131
Vallès, Grijpink-Ongering, de Bree, Tuinstra, Ronken: Differential regulation of the CXCR2 chemokine network in rat brain trauma: implications for neuroimmune interactions and neuronal survival. dans Neurobiology of disease 2006
Human Polyclonal CXCL1 Primary Antibody pour ELISA - ABIN4274952
Kawanishi, Matsui, Ito, Watanabe, Takahashi, Nishizawa, Nishiyama, Kamoto, Mikami, Tanaka, Jung, Akiyama, Nobumasa, Guilford, Reeve, Okuno, Tsujimoto, Nakamura, Ogawa: Secreted CXCL1 is a potential mediator and marker of the tumor invasion of bladder cancer. dans Clinical cancer research : an official journal of the American Association for Cancer Research 2008
this study demonstrates that in vivo blocking of CXCL1 and CXCL2 (Montrer CXCL2 Anticorps) can significantly reduce the Mycobacterium tuberculosis-induced bioactive IL-1beta (Montrer IL1B Anticorps) production
RelA (Montrer NFkBP65 Anticorps) has a role in regulating OIS in preneoplastic lesions; the RelA (Montrer NFkBP65 Anticorps)/CXCL1/CXCR2 (Montrer CXCR2 Anticorps) axis is an essential mechanism of tumor surveillance in pancreatic ductal adenocarcinoma
CXCL1 contributed to rapid neutrophil recruitment during Bacillus cereus endophthalmitis. In CXCL1-knockout mice, retinal function was greater and neutrophil influx was less than in control mice, confirming its role in ocular inflammation.
Interferon-gamma (IFN-gamma (Montrer IFNG Anticorps)) up-regulated interleukin 6 (IL-6 (Montrer IL6 Anticorps)) and CXCL1 chemokine (Montrer CCL1 Anticorps) (CXCL1) production of bone marrow mesenchymal stem cells (mBM-MSC (Montrer MSC Anticorps)).
MMP7 (Montrer MMP7 Anticorps) shedding of syndecan-1 (Montrer SDC1 Anticorps)/CXCL1 complexes functions as a checkpoint that restricts neutrophil activation at sites of epithelial injury.
Data show that loss of loss of matrix metalloproteinase-3 (MMP-3 (Montrer MMP3 Anticorps)) repressed the upregulation of the chemokines monocyte chemoattractant protein (MCP)-1 (Montrer CPT1B Anticorps) and (C-X-C motif) ligand 1 (CXCL1).
CXCR2 (Montrer CXCR2 Anticorps)/CXCL1 axis promotes granulocytic myeloid-derived suppressor cells recruitment and facilitates arginase I (Montrer ARG1 Anticorps) expression and activity of these cells at maternal-fetal interface
The novel findings reveal the critical role of NLRP12 (Montrer NLRP12 Anticorps)-IL-17A (Montrer IL17A Anticorps)-CXCL1 axis in host defense by modulating neutrophil recruitment against Klebsiella pneumoniae.
Nlrp12 (Montrer NLRP12 Anticorps) deficiency caused increased neutrophil migration towards the chemokine (Montrer CCL1 Anticorps) CXCL1 and the neutrophil parasite Leishmania major, revealing NLRP12 (Montrer NLRP12 Anticorps) as a negative regulator of directed neutrophil migration under these conditions.
CXCL1 monomer-dimer distribution and receptor interactions are highly coupled and regulate neutrophil trafficking and that injury in the context of disease is a consequence of inappropriate CXCR2 (Montrer CXCR2 Anticorps) activation
Taken together, the present study indicates that IL-33 (Montrer IL33 Anticorps) localized in the human atherosclerotic plaque increases GRO-alpha mRNA expression and protein secretion via activation of ERK1/2 (Montrer MAPK1/3 Anticorps), JNK (Montrer MAPK8 Anticorps), and NF-kappaB (Montrer NFKB1 Anticorps) in HUVECs, suggesting that IL-33 (Montrer IL33 Anticorps) plays an important role in the pathophysiology and development of atherosclerosis.
Study provides the first evidence that primary malignant cell-secreted VEGFA (Montrer VEGFA Anticorps) stimulates tumor-associated macrophages to produce CXCL1, which recruits CXCR2 (Montrer CXCR2 Anticorps)-positive MDSCs to form a premetastatic niche to promote liver metastases.
the presence of elevated circulating levels of VEGF (Montrer VEGFA Anticorps) and CXCL1 are predictive of liver and lung metastasis, respectively of colorectal cancer.
This study describe elevated levels of CXCL1 and it receptor in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma, relative to other pediatric brain tumors and normal cerebral tissue.
The expressions of CXCL1 in cancer cells and CXCR2 (Montrer CXCR2 Anticorps) in stromal cells are useful prognostic factors for gastric cancer patients
CXCL1 secreted by tumor-associated lymphatic endothelial cells promotes lymph node metastasis of gastric cancer through integrin beta1/FAK (Montrer PTK2 Anticorps)/AKT (Montrer AKT1 Anticorps) signaling pathway.
S100A9 (Montrer S100A9 Anticorps) and S100A12 (Montrer S100A12 Anticorps) may have a role in the pathogenesis of pneumonia: S100A9 (Montrer S100A9 Anticorps) and CXCL1 may contribute solely in mild pneumonia, and CCL5 (Montrer CCL5 Anticorps) and CXCL11 (Montrer CXCL11 Anticorps) may contribute in severe pneumonia.
These findings support a role for CXCL1 and IL-8 (Montrer IL8 Anticorps) in cystic fibrosis (Montrer S100A8 Anticorps) lung disease severity and identify STAT3 (Montrer STAT3 Anticorps) as a modulating pathway.
Results suggest that CXCL1 is a key molecular link between senescence of stromal fibroblasts and tumor growth.
Increased IL-8 (Montrer IL8 Anticorps) and CXCL1 transcription in T84 and THP-1 (Montrer GLI2 Anticorps) cells compared to that in wild-type EPEC.
This gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signal through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.
, growth-regulated alpha protein
, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
, melanoma growth stimulatory activity homolog
, C-X-C motif chemokine 1
, cytokine-induced neutrophil chemoattractant 1
, platelet-derived growth factor-inducible protein KC
, GRO1 oncogene
, secretory protein N51
, growth regulated protein GRO
, growth regulated
, GRO1 oncogene (melanoma growth stimulating activity, alpha)
, GRO1 oncogene (melanoma growth-stimulating activity)
, MGSA alpha
, fibroblast secretory protein
, melanoma growth stimulatory activity alpha
, neutrophil-activating protein 3
, growth related gene 1
, growth-regulated protein homolog alpha