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anti-Mouse (Murine) LGALS1 Anticorps:
anti-Human LGALS1 Anticorps:
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Mouse (Murine) Polyclonal LGALS1 Primary Antibody pour CyTOF, ELISA (Capture) - ABIN4899423
Silva-Monteiro, Reis Lorenzato, Kenji Nihei, Junqueira, Rabinovich, Hsu, Liu, Savino, Chammas, Villa-Verde: Altered expression of galectin-3 induces cortical thymocyte depletion and premature exit of immature thymocytes during Trypanosoma cruzi infection. dans The American journal of pathology 2007
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Human Polyclonal LGALS1 Primary Antibody pour CyTOF, FACS - ABIN4899422
Yazawa, Geddes-Sweeney, Cedeno-Laurent, Walley, Barthel, Opperman, Liang, Lin, Schatton, Laga, Mihm, Qureshi, Widlund, Murphy, Dimitroff: Melanoma Cell Galectin-1 Ligands Functionally Correlate with Malignant Potential. dans The Journal of investigative dermatology 2015
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Human Polyclonal LGALS1 Primary Antibody pour IHC, IHC (p) - ABIN4313208
Ek, Andréasson, Hober, Kampf, Pontén, Uhlén, Merz, Borrebaeck: From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies. dans Molecular & cellular proteomics : MCP 2006
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Human Monoclonal LGALS1 Primary Antibody pour IF, IP - ABIN561662
Tan, Tan, Lin, Lim, Hew, Chung: Quantitative and temporal proteome analysis of butyrate-treated colorectal cancer cells. dans Molecular & cellular proteomics : MCP 2008
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Human Polyclonal LGALS1 Primary Antibody pour IF, IHC (p) - ABIN2473743
Resnick: Should the "worst case scenario" be universal for chloramines? dans Nephrology news & issues 1990
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Human Polyclonal LGALS1 Primary Antibody pour ELISA, WB - ABIN2473744
Camby, Le Mercier, Lefranc, Kiss: Galectin-1: a small protein with major functions. dans Glycobiology 2006
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Human Polyclonal LGALS1 Primary Antibody pour IF (p), IHC (p) - ABIN718586
Jayachandran, Lugo, Heiling, Miller, Rule, Lieske: Extracellular vesicles in urine of women with but not without kidney stones manifest patterns similar to men: a case control study. dans Biology of sex differences 2015
Human Polyclonal LGALS1 Primary Antibody pour IF, WB - ABIN517485
Doe, Wuebbles, Allred, Rooney, Elorza, Burkin: Transgenic overexpression of the ?7 integrin reduces muscle pathology and improves viability in the dy(W) mouse model of merosin-deficient congenital muscular dystrophy type 1A. dans Journal of cell science 2011
Human Monoclonal LGALS1 Primary Antibody pour ELISA, FACS - ABIN5582500
Couraud, Casentini-Borocz, Bringman, Griffith, McGrogan, Nedwin: Molecular cloning, characterization, and expression of a human 14-kDa lectin. dans The Journal of biological chemistry 1989
findings show that galectin-1 (Gal-1), an immunoregulatory lectin widely expressed in mucosal tissues, contributes to Y. enterocolitica pathogenicity by undermining protective antibacterial responses.
Gal-1 functions as an important regulator in RNV and offers a promising strategy for the treatment of RNV diseases, such as proliferative diabetic retinopathy and retinopathy of prematurity.
These findings demonstrate that galectin-1 is required for i.v. tolerance induction, likely via induction of tolerogenic DCs leading to enhanced development of Tr1 (Montrer TXNRD1 Anticorps) cells, Treg cells, and downregulation of proinflammatory responses.
this study shows that galectin-1 secreted by Sertoli cells plays a pivotal role in the differentiation of functionally tolerogenic dendritic cells
analysis of the effect of low-temperature plasma on the expression of galectin-1, -2, and -3 in the healing skin compared with those of electrocoagulation conducted with a high-frequency electrical coagulator
Tumor-driven, unremitting expression of Satb1 (Montrer SATB1 Anticorps) in activated Zbtb46 (Montrer ZNF340 Anticorps)+ inflammatory dendritic cells that infiltrate ovarian tumors results in an immunosuppressive phenotype characterized by increased secretion of tumor-promoting Galectin-1 and IL-6 (Montrer IL6 Anticorps).
Gal-1 does not play a role in the systemic immunosuppressive effect of Mesenchymal stem cells.
Galectin-1 has a role in driving lymphoma CD20 (Montrer MS4A1 Anticorps) immunotherapy resistance in a mouse model
These findings highlight the importance of the inflammatory micro-environment of mucosal tissues in modulating intestinal epithelial cells susceptibility to the immunoregulatory lectin Gal-1 and its role in epithelial cell homeostasis.
results unveil a dual role of endogenous versus exogenous Gal-1 in the control of autoimmune testis inflammation.
Galectin-1-driven production of SDF-1 (Montrer CXCL12 Anticorps) in pancreatic stellate cells through activation of NF-kappaB (Montrer NFKB1 Anticorps) promotes metastasis in pancreatic ductal adenocarcinoma.
Gal-1 expression by MM cells was upregulated in hypoxic conditions and stable knockdown of hypoxia inducible factor-1alpha significantly downregulated its expression
Gal1 may be a useful marker for determining whether morphologic changes in oral cells are reactive or neoplastic
The aim of this study was to analyze the syncytium formation abilities of BeWo cells that were gal-1 silenced.
Studies provide evidence that galectin-1 belongs to the group of potential pathogenic molecules in systemic lupus erythematosus. [review]
an intact dimer interface of Gal-1 is required for it to positively regulate H-rasG12V nanoclustering, but negatively K-rasG12V nanoclustering.
Our results suggest that Gal-1 and ASPP2 functionally compete in nanocluster for active Ras on the plasma membrane. ASPP2 dominates the biological outcome, thus switching from a Gal-1 supported growth-promoting setting to a senescence inducing and stemness suppressive program in cancer cells. Our results support Ras nanocluster as major integrators of tumour fate decision events.
Galectin-1 and Galectin-3 (Montrer LGALS3 Anticorps) are novel-binding partners for human FVIII (Montrer F8 Anticorps). Gal-1 binding can influence the procoagulant activity of FVIII (Montrer F8 Anticorps).
Proteomics of the interstitial fluid in subcutaneous adipose tissue in vivo identified a novel adipokine, galectin-1, with a potential role in the pathophysiology of type 2 diabetes.
Suggest that galectin-1 is a protective factor against the development of digital vasculopathy in systemic sclerosis.
Data suggest that galectin-1 and VEGFR-2 (Montrer KDR Anticorps) are expressed at mid-luteal stages in luteal cells of corpus luteum; galectin-1 binds directly to asparagine-linked glycans (N-glycans) on VEGFR-2 (Montrer KDR Anticorps) in luteal cells.
The relative abundance of PIBF (Montrer PIBF1 Anticorps), LGALS1, LGALS3 (Montrer LGALS2 Anticorps), LGALS3BP (Montrer LGALS3BP Anticorps), and LGALS9 (Montrer LGALS9 Anticorps) mRNA would display a differential expression pattern in the endometrium.
The binding affinity and specificity of galectin-1 for eight different beta-galactosyl terminal disaccharides was studied using molecular-dynamics simulations.
Gal-1 may serve as an adhesion molecule (Montrer NCAM1 Anticorps) to interact with both cells and laminins
Gal-1 is expressed in a wide range of porcine tissues, including striated (Montrer NSDHL Anticorps) muscle, liver, lung, brain, kidney, spleen, and intestine
LGALS1 was found widely expressed in all tissues and transient transfection indicated that galectin-1 locates both in cytoplasm and nucleus.
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation.
lectin, galactoside-binding, soluble, 1
, galectin 1
, lectin, galactoside-binding, soluble, 1 (galectin 1)
, 14 kDa lectin
, 14K beta-galactoside-binding lectin
, beta-galactoside-binding lectin
, galectin CG-1B
, Beta-galactoside-binding lectin L-14-I
, Lactose-binding lectin 1
, Lectin galactoside-binding soluble 1
, S-Lac lectin 1
, beta-galactoside binding protein
, beta-galactoside-binding lectin L-14-I
, lactose-binding lectin 1
, lectin galactoside-binding soluble 1
, 14 kDa laminin-binding protein
, beta-galactoside-binding protein 14kDa
, putative MAPK-activating protein PM12
, RL 14.5
, lectin, galactose binding, soluble 1