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anti-Human MTA1 Anticorps:
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Human Polyclonal MTA1 Primary Antibody pour IHC, IHC (p) - ABIN153200
Khaleque, Bharti, Gong, Gray, Sachdev, Ciocca, Stati, Fanelli, Calderwood: Heat shock factor 1 represses estrogen-dependent transcription through association with MTA1. dans Oncogene 2008
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Human Polyclonal MTA1 Primary Antibody pour WB - ABIN1881556
Zhu, Guo, Li, Ding, Chen: Metastasis-associated protein 1 nuclear expression is associated with tumor progression and clinical outcome in patients with non-small cell lung cancer. dans Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2010
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Human Polyclonal MTA1 Primary Antibody pour ELISA, WB - ABIN257636
Toh, Pencil, Nicolson: A novel candidate metastasis-associated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines. cDNA cloning, expression, and protein analyses. dans The Journal of biological chemistry 1994
Findings illustrate how cancer cells utilize a chromatin remodeling factor (Montrer ASH1L Anticorps) to engage a core survival pathway to support its cancerous phenotypes, and reveal new facets of MTA1-SGK1 (Montrer SGK1 Anticorps) axis by a physiologic signal in cancer progression.
Downregulation of miR (Montrer MLXIP Anticorps)-30e can increase levels of MTA1 in human hepatocellular carcinoma, and furthermore promote cell invasion and metastasis by promoting ErbB2 (Montrer ERBB2 Anticorps).
In subgroup analyses based on study quality and tumor type, MTA1 overexpression was obviously related to clinical parameters, such as lymph node metastasis and TNM (Montrer ODZ1 Anticorps) stage, and was also associated with prognosis of patients with gastrointestinal or esophageal cancer
Our findings revealed that miR (Montrer MLXIP Anticorps)-183 upregulation and MTA1 gene silence significantly repressed the epithelial-mesenchymal transition, migration and invasion of human pancreatic cancer cells.
MTA1 expression was positively correlated with LAT1 (Montrer LAT Anticorps) (p=0.013) and CD34 (Montrer CD34 Anticorps) (p=0.034) expression, but not with Ki-67 (Montrer MKI67 Anticorps) (p=0.078). MTA1 shows promise as a diagnostic and prognostic marker in esophageal cancer, and we anticipate that the gene will also prove to be a good therapeutic target.
In this study, we aimed to analyze the expression of miR (Montrer MLXIP Anticorps)-183 and MTA1 in nasopharyngeal carcinoma tissues and cells; explore the role of miR (Montrer MLXIP Anticorps)-183 in NPC (Montrer NPC1 Anticorps) cell proliferation, invasion, as well as DDP (Montrer TIMM8A Anticorps)-induced apoptosis; and investigate the relationship between miR (Montrer MLXIP Anticorps)-183 and MTA1 in nasopharyngeal carcinoma cells.
Metastasis-associated protein-1 expression levels in HPV-infected non-small cell lung cancer tissues correlated positively with tumor stage and nodal metastasis.
our studies indicate that Curcumin increases the sensitivity of Paclitaxel-resistant non-small-cell lung cancer cells to Paclitaxel through microRNA-30c-mediated MTA1 reduction. Curcumin might be a potential adjuvant for non-small-cell lung cancer patients during Paclitaxel treatment.
Data show that metastasis associated 1 (MTA1) represses neuronal nitric oxide synthase (nNOS (Montrer NOS1 Anticorps)) expression upon oxygen glucose deprivation (OGD (Montrer FGFR1 Anticorps))-induced oxidative stress.
Data indicate a positive correlation between metastasis-associated protein 1 (MTA1) and microRNA miR (Montrer MLXIP Anticorps)-22, supporting their inhibitory effect on E-cadherin (Montrer CDH1 Anticorps) expression.
the augmentation of endogenous MTA1 expression during neuronal ischemic injury acts additionally to an endocrinous cascade orchestrating intimate interactions between ERalpha (Montrer ESR1 Anticorps) and BCL2 (Montrer BCL2 Anticorps) pathways.
Findings highlight MTA1 as a key upstream regulator of prostate tumorigenesis and cancer progression.
Inhibition of MTA1 expression by in vivo siRNA treatment exacerbated the pathology of LPS (Montrer TLR4 Anticorps)-induced acute lung injury, by selectively promoting the expression of NF-kappaB (Montrer NFKB1 Anticorps)-regulated inflammatory cytokines.
MTA1 was regulated by HIF-1alpha (Montrer HIF1A Anticorps) in hypoxia circumstance to suppress osteoblast differentiation.
MTA1 levels were increased in monosodium urate crystal-induced inflammation.
The inhibition of MTA1 gene could depress the growth and metastasis of laryngeal squamous cell carcinoma in nude mice.
Data suggest that nuclear metastasis-associated protein 1 (MTA1) is a good marker for cancer differentiation diagnosis and a potential target for the treatment of cancers.
this study reports the potential signaling events related to up-regulation of metastasis associated protein 1 (Mta1), a master chromatin modifier, during mono-(2-ethylhexyl) phthalate (MEHP)-induced Sertoli cells injury.
MTA1 has an important role in the maintenance of circadian rhythmicity.
Findings suggest that Mta3-NuRD complex, inclding component HDAC1 (Montrer HDAC1 Anticorps), is essential for the initiation of primitive hematopoiesis.
This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene.
metastasis associated gene 1 protein
, metastasis-associated protein MTA1
, metastasis associated family, member 3
, metastasis-associated protein MTA3