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Aperçu des produits pour anti-Insulin Receptor Substrate 1 (IRS1) Anticorps

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anti-Insulin Receptor Substrate 1 Anticorps (IRS1)
Chez sont 593 Insulin Receptor Substrate 1 (IRS1) Anticorps de 30 de différents fournisseurs disponibles. De plus, nous expédions Insulin Receptor Substrate 1 Kits (45) et Insulin Receptor Substrate 1 Protéines (6) et beaucoup plus de produits pour cette protéine. Un total de 668 Insulin Receptor Substrate 1 produits sont actuellement listés.
G972R, HIRS-1, irs-1, IRS1, irs1-a, IRS1IRM, irsu

Réactivités les plus populaires pour anti-Insulin Receptor Substrate 1 (IRS1) Anticorps

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anti-Insulin Receptor Substrate 1 Anticorps mieux référencés

  1. Human Polyclonal IRS1 Primary Antibody pour EIA, IF - ABIN500072 : Giovannone, Scaldaferri, Federici, Porzio, Lauro, Fusco, Sbraccia, Borboni, Lauro, Sesti: Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential. dans Diabetes/metabolism research and reviews 2001 (PubMed)
    Show all 4 references for ABIN500072

  2. Human Polyclonal IRS1 Primary Antibody pour IHC (p), WB - ABIN196978 : Ozes, Akca, Mayo, Gustin, Maehama, Dixon, Donner: A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1. dans Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)
    Show all 4 references for ABIN196978

  3. Human Polyclonal IRS1 Primary Antibody pour IF, IHC - ABIN1531876 : Simon-Szabó, Kokas, Mandl, Kéri, Csala: Metformin attenuates palmitate-induced endoplasmic reticulum stress, serine phosphorylation of IRS-1 and apoptosis in rat insulinoma cells. dans PLoS ONE 2014 (PubMed)
    Show all 2 references for ABIN1531876

  4. Human Polyclonal IRS1 Primary Antibody pour EIA - ABIN118052 : Cho, Nam, An, Lim: Replicable and shape-controllable fabrication of electrospun fibrous scaffolds for tissue engineering. dans Journal of nanoscience and nanotechnology 2013 (PubMed)
    Show all 2 references for ABIN118052

  5. Human Polyclonal IRS1 Primary Antibody pour ELISA, WB - ABIN129580 : Shah, Hunter: Turnover of the active fraction of IRS1 involves raptor-mTOR- and S6K1-dependent serine phosphorylation in cell culture models of tuberous sclerosis. dans Molecular and cellular biology 2006 (PubMed)

  6. Human Polyclonal IRS1 Primary Antibody pour IF, IHC - ABIN1532908 : Araki, Sun, Haag, Chuang, Zhang, Yang-Feng, White, Kahn: Human skeletal muscle insulin receptor substrate-1. Characterization of the cDNA, gene, and chromosomal localization. dans Diabetes 1993 (PubMed)

Plus d’anticorps contre Insulin Receptor Substrate 1 partenaires d’interaction

Pig (Porcine) Insulin Receptor Substrate 1 (IRS1) interaction partners

  1. TBC1D4 (Montrer TBC1D4 Anticorps), insulin receptor (Montrer INSR Anticorps) and GLUT4 (Montrer SLC2A4 Anticorps) showed altered expression in some tissues in pre-diabetic pigs.

  2. Association analysis of genotypes with growth traits, anatomy traits, meat quality traits and physiological biochemical indexes traits showed that different genotypes at locus 3,257 of IRS-1 have significant differences in carcass straight length in pigs.

Human Insulin Receptor Substrate 1 (IRS1) interaction partners

  1. Findings suggest that insulin receptor substrate -1 Gly972Arg polymorphism is associated with polycystic ovary syndrome in the Caucasian ethnicity, and insulin receptor substrate -2 (Montrer IRS2 Anticorps) Gly1057Asp polymorphism is correlated with polycystic ovary syndrome in the Asian ethnicity. However, insulin receptor (Montrer INSR Anticorps) His 1058 C/T polymorphism may not be implicated in polycystic ovary syndrome.

  2. IRS1 Gene Polymorphism is associated with Autism Spectrum Disorder.

  3. High IRS1 expression is associated with hepatocellular carcinoma.

  4. In the renal proximal tubule, insulin (Montrer INS Anticorps) signaling via IRS1 is inhibited, while insulin (Montrer INS Anticorps) signaling via IRS2 (Montrer IRS2 Anticorps) is preserved. Insulin (Montrer INS Anticorps) signaling via IRS2 (Montrer IRS2 Anticorps) continues to stimulate sodium reabsorption in the proximal tubule and causes sodium retention, edema, and hypertension.

  5. miR-195 inhibits tumor angiogenesis through suppressing IRS1-VEGF axis.

  6. The Arg(972) IRS-1 polymorphism is associated with increased risk and disease activity/severity of rheumatoid arthritis, and therefore may be a potential prognostic factor for RA.

  7. In this exploratory analysis, IRS1, ENNP1 and TRIB3 (Montrer TRIB3 Anticorps), known to be associated with type 2 diabetes and harboring genes playing a prominent role in mediating insulin (Montrer INS Anticorps) signaling, may modulate a number of cardiometabolic phenotypes in patients of Italian ancestry with newly-diagnosed type 2 diabetes.

  8. In accordance with previous studies, our findings suggest that the IRS1 G972R R allele and RR+GR genotype have protective effects for colorectal cancer (CRC (Montrer CALR Anticorps)) in overweight/obese patients and for obesity in patients with CRC (Montrer CALR Anticorps).

  9. FRET-based translocation assays reveal that insulin (Montrer INS Anticorps) promotes the association of both p62 (Montrer GTF2H1 Anticorps) and aPKC with the insulin (Montrer INS Anticorps)-regulated scaffold IRS-1.

  10. HCV NS5A favors serine phosphorylation of IRS-1, promoting insulin (Montrer INS Anticorps) resistance through IRS-1 serine phosphorylation and increased gluconeogenesis.

Mouse (Murine) Insulin Receptor Substrate 1 (IRS1) interaction partners

  1. Acute knockdown of Insr (Montrer INSR Anticorps) or both Irs1 and Irs2 (Montrer IRS2 Anticorps) in adipocytes increased Adipoq (Montrer ADIPOQ Anticorps) mRNA expression but reduced adiponectin (Montrer ADIPOQ Anticorps) secretion.

  2. Concentration of SOCS-3 (Montrer SOCS3 Anticorps) protein and coimmunoprecipitation of SOCS-3 (Montrer SOCS3 Anticorps) protein with both the IR-beta subunit (Montrer POLG Anticorps) as well as IRS-1 was found to be decreased by 4-HIL

  3. Authors propose that insulin (Montrer INS Anticorps)/IGF-1 (Montrer IGF1 Anticorps) cross talk and level of phosphorylation of specific IRS-1 serines may promote the Ames dwarf (Montrer PROP1 Anticorps) longevity phenotype.

  4. within the hepatic compartment, mTORC1 --> S6K (Montrer RPS6KB1 Anticorps) signaling regulates Akt (Montrer AKT1 Anticorps) largely through IRS (Montrer IARS Anticorps)-independent means with little effect upon physiologic insulin (Montrer INS Anticorps) sensitivity.

  5. Sustained overexpression of HBx and IRS1 led to constitutive activation of a tripartite growth factor signal transduction cascade in the liver and was necessary and sufficient to promote HCC (Montrer FAM126A Anticorps) development and progression.

  6. Insulin receptor substrate-1-mediated insulin (Montrer INS Anticorps) signal transduction may be an important factor in the treatment of cognitive decline induced by insulin (Montrer INS Anticorps) resistance.

  7. Full Length Irs-1 transcript functions as a bifunctional RNA during myogenic differentiation.

  8. melatonin can ameliorate insulin (Montrer INS Anticorps) sensitivity by inhibiting Ser307 phosphorylation in IRS-1

  9. Most importantly, treatment of cells with the RhoA (Montrer RHOA Anticorps)/ROCK inhibitor, Y-27632, which among its many effects also inhibited serine 636 phosphorylation of IRS-1, had profound effects on cell-substratum adhesion

  10. Results indicate that although IRS (Montrer IARS Anticorps) isoforms (irs1 and irs2 (Montrer IRS2 Anticorps)) play divergent roles in the developmental regulation of cardiac size, these isoforms exhibit nonredundant roles in mediating the hypertrophic and metabolic response of the heart to exercise.

Rabbit Insulin Receptor Substrate 1 (IRS1) interaction partners

  1. IRS1 gene was associated with growth traits in rabbits.Association between the IRS1 and FTO (Montrer FTO Anticorps) genes regulates body weight in rabbits.

Xenopus laevis Insulin Receptor Substrate 1 (IRS1) interaction partners

  1. Knock down of IRS-1 in neural tissue by specific antisense morpholino oligonucleotides (MO) resulted in abnormal eye formation accompanied by reduction of the eye-specific marker genes Rx1 and Pax6 (Montrer PAX6 Anticorps) and a decreased cell proliferation.

Insulin Receptor Substrate 1 (IRS1) profil antigène

Antigen Summary

This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.

Alternative names and synonyms associated with Insulin Receptor Substrate 1 (IRS1)

  • insulin receptor substrate 2 (irs2) anticorps
  • insulin receptor substrate 1 (IRS1) anticorps
  • insulin receptor substrate 1 (Irs1) anticorps
  • insulin receptor substrate 1 (irs1) anticorps
  • G972R anticorps
  • HIRS-1 anticorps
  • irs-1 anticorps
  • IRS1 anticorps
  • irs1-a anticorps
  • IRS1IRM anticorps
  • irsu anticorps

Protein level used designations for IRS1

IRS-1 , insulin receptor substrate 1 , pp185 , XIRS-L , insulin receptor substrate 1-A , xIRS-1-A

394823 Xenopus (Silurana) tropicalis
429126 Gallus gallus
459985 Pan troglodytes
100271862 Felis catus
100294708 Sus scrofa
100607873 Nomascus leucogenys
3667 Homo sapiens
16367 Mus musculus
25467 Rattus norvegicus
429262 Gallus gallus
538598 Bos taurus
100512686 Sus scrofa
100716939 Cavia porcellus
486148 Canis lupus familiaris
100339981 Oryctolagus cuniculus
101102293 Ovis aries
399299 Xenopus laevis
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