IRS1 anticorps (pTyr612)

N° du produit ABIN540934

Détail du produit anti-IRS1 anticorps

Antigène: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Épitope: pTyr612

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Dot Blot (DB)

Fonction: Rabbit polyclonal antibody raised against synthetic phosphopeptide of IRS1.

Séquence: DGYMP

Specificité: This antibody recognizes ~165 KDa of human IRS1 (pTyr 612).

Réactivité croisée: Humain, Souris, Rat

Immunogène: Synthetic phosphopeptide corresponding to residues surrounding Y612 of human IRS1.

Isotype: IgG

Information d'application

Indications d'application: Western Blot (0.1-1 μg/mL)
ELISA (0.01-0.1 μg/mL)
Immunoprecipitation (2-5 μg/mL)
Immunohistochemistry (0.5-2 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In TBS, pH 7.2 (BSA, 10 % Proclin300)

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-IRS1 (ABIN540934)

Li, Soos, Li, Wu, Degennaro, Sun, Littman, Birnbaum, Polakiewicz: "Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101)." dans: The Journal of biological chemistry, Vol. 279, Issue 44, pp. 45304-7, (2004) (PubMed).

Détails sur IRS1

Antigène: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Autre désignation: IRS1 (IRS1 Produits)

Synonymes: anticorps HIRS-1, anticorps G972R, anticorps IRS-1, anticorps IRS1IRM, anticorps irs1, anticorps irsu, anticorps IRS1, anticorps irs-1, anticorps irs1-a, anticorps insulin receptor substrate 1, anticorps insulin receptor substrate 2, anticorps insulin receptor substrate 1 S homeolog, anticorps IRS1, anticorps Irs1, anticorps irs2, anticorps irs1.S

ID gène: 3667

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process