Aperçu des produits pour anti-Filamin A (FLNA) Anticorps

Full name:
anti-Filamin A, alpha Anticorps (FLNA)
Chez www.anticorps-enligne.fr sont 154 Filamin A, alpha (FLNA) Anticorps de 18 de différents fournisseurs disponibles. De plus, nous expédions Filamin A Kits (32) et Filamin A Protéines (3) et beaucoup plus de produits pour cette protéine. Un total de 195 Filamin A produits sont actuellement listés.
Synonymes:
ABP-280, ABPX, cb967, CG3937, Cher, CSBS, CVD1, Dilp2, Dmel\\CG3937, F730004A14Rik, fb98b06, Fil, filamin-1, FLN, FLN-A, Fln1, flna, FMD, joy, MGC147094, MNS, NHBP, OPD, OPD1, OPD2, RGD1560614, sko, wu:fb98b06, wu:fd09g03, wu:fd18g06, wu:fd49a06, XLVD, XMVD

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anti-Human Filamin A Anticorps:

anti-Rat (Rattus) Filamin A Anticorps:

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anti-Filamin A Anticorps mieux référencés

  1. Human Monoclonal Filamin A Primary Antibody pour IHC (p), PLA - ABIN560922 : Valente, Logan, Mougou-Zerelli, Lee, Silhavy, Brancati, Iannicelli, Travaglini, Romani, Illi, Adams, Szymanska, Mazzotta, Lee, Tolentino, Swistun, Salpietro, Fede, Gabriel, Russ, Cibulskis, Sougnez et al.: Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes. ... dans Nature genetics 2010 (PubMed)
    Show all 7 references for 560922

  2. Human Monoclonal Filamin A Primary Antibody pour WB - ABIN1882243 : Gorlin, Yamin, Egan, Stewart, Stossel, Kwiatkowski, Hartwig: Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring. dans The Journal of cell biology 1990 (PubMed)
    Show all 6 references for 1882243

  3. Human Polyclonal Filamin A Primary Antibody pour ICC, IF - ABIN188803 : Thoms, Loveridge, Simpson, Clipson, Reinhardt, Dunlop, Stark: Nucleolar targeting of RelA(p65) is regulated by COMMD1-dependent ubiquitination. dans Cancer research 2010 (PubMed)
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  4. Human Polyclonal Filamin A Primary Antibody pour FACS, IF - ABIN392193 : Maceyka, Alvarez, Milstien, Spiegel: Filamin A links sphingosine kinase 1 and sphingosine-1-phosphate receptor 1 at lamellipodia to orchestrate cell migration. dans Molecular and cellular biology 2008 (PubMed)

Plus d’anticorps contre Filamin A partenaires d’interaction

Zebrafish Filamin A, alpha (FLNA) interaction partners

  1. Knockdown of filamin A or vimentin (Montrer VIM Anticorps) in normal cells profoundly suppresses apical extrusion of the neighbouring transformed cells.

Fruit Fly (Drosophila melanogaster) Filamin A, alpha (FLNA) interaction partners

  1. Here we show using Drosophila indirect flight mus (Montrer KPTN Anticorps)cle that t (Montrer FLNC Anticorps)he filamin ortholog Cheerio in conjunction with the giant elastic protein titin plays a crucial role in keeping thin filaments stably anchored at the Z-disc. We identify the filamin domains required for interaction with the (Montrer TTN Anticorps) titin ortholog Sallimus, and we demonstrate a genetic interaction of filamin with titin and actin.

  2. study identifies Cher as a new target of JNK (Montrer MAPK8 Anticorps) signaling that links cytoskeleton dynamics to tumor progression.

  3. Data indicate that during embryonic development, the expression of Filamin and Ten-m partially overlap in ectodermal cells.

  4. Filamin is required for ovarian follicle cell motility during oogenesis.

Human Filamin A, alpha (FLNA) interaction partners

  1. CCR2B (Montrer CCR2 Anticorps) and beta2AR (Montrer ADRB2 Anticorps) signals to FLNa to stimulate its endocytosis and recycling to the plasma membrane.

  2. In humans, mutations in the actin-binding protein (Montrer KPTN Anticorps) Filamin-C (Montrer FLNC Anticorps) result in myopathies, but the underlying molecular function is not well understood. Here we show using Drosophila indirect flight muscle that the filamin ortholog Cheerio in conjunction with the giant elastic protein titin (Montrer TTN Anticorps) plays a crucial role in keeping thin filaments stably anchored at the Z-disc

  3. Case Report: Reduced binding of mutant FLNa to beta3 and the facilitated recruitment of talin by beta3 on platelet stimulation, explaining the increased alphaIIbbeta3 activation and the ensuing gain-of-platelet functions.

  4. results reveal an unusual structural and thermodynamic basis for the P2204L-induced dysfunction of filamin and frontometaphyseal dysplasia disease.

  5. Mechanistic analysis revealed that FLNA suppresses pol III gene transcription by confining the recruitment of the RNA pol III transcription machinery at the promoters of the genes that are sensitive to the alteration of FLNA expression.

  6. FlnA more strongly binds RhoA (Montrer RHOA Anticorps), although both filamins overlap with RhoA (Montrer RHOA Anticorps) expression in the cell cytoplasm. FlnA promotes RhoA (Montrer RHOA Anticorps) activation whereas FlnB (Montrer FLNB Anticorps) indirectly inhibits this pathway. Moreover, FlnA loss leads to diminished expression of b1-integrin, whereas FlnB (Montrer FLNB Anticorps) loss promotes integrin expression

  7. FLNA can function as a modulator of chemosensitivity to docetaxel in triple-negative breast cancer (TNBC) cells through regulation of the MAPK/ERK (Montrer MAPK1 Anticorps) pathway both in vitro and in vivo. FLNA may serve as a novel therapeutic target for improvement of chemotherapy efficacy in TNBC.

  8. Results indicate that mTORC2 (Montrer CRTC2 Anticorps) regulates filamin A-dependent focal adhesions and cell migration.

  9. the actin-binding protein (Montrer KPTN Anticorps) filamin-A has a critical role in incorporation of Tissue factor (Montrer F3 Anticorps) into extracellular vesicles and secretion of extracellular vesicles from ovarian cancer cells exposed to hypoxia

  10. The syndrome affecting the family shares phenotypic overlap with other syndromes caused by FLNA mutations, but appears to be a distinct phenotype, likely representing a unique genetic syndrome.

Pig (Porcine) Filamin A, alpha (FLNA) interaction partners

  1. filamin reduces ENaC (Montrer SCNN1A Anticorps) channel function through direct interaction on the cell surface

Mouse (Murine) Filamin A, alpha (FLNA) interaction partners

  1. FlnA binding to PACSIN2 (Montrer PACSIN2 Anticorps) F-BAR domain regulates membrane tubulation in megakaryocytes and platelets.

  2. FlnA is a critical upstream element of the signaling cascade underlying the myogenic tone.

  3. Bones lacking filamin A are protected from estrogen-mediated post-menopausal osteoporosis

  4. findings suggest a model in which filamin A local translation following axon injury controls localized HDAC5 (Montrer HDAC5 Anticorps) activity to promote axon regeneration.

  5. Deletion of filamin A in endothelial cells aggravated myocardial infarction-induced left ventricle dysfunction and cardiac failure as a result of defective endothelial response

  6. A new signaling set, phosphatidic acid-S6K1-FLNA-actin, sheds light into the morphogenic pathway of cytoskeletal structures that are crucial for adhesion and cell locomotion during inflammation and metastasis.

  7. Filamin-A is associated with neutrophil uropod retraction.

  8. Analysis of editing in the filamin A encoding mRNA shows very high editing levels outside the nervous system; further shows FLNA editing is mainly achieved by ADAR2 (Montrer ADARB1 Anticorps) but that in some cases ADAR1 (Montrer ADAR Anticorps) can efficiently compensate for ADAR2 (Montrer ADARB1 Anticorps).

  9. Filamin a, b-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeleton.

  10. a major function of FLNa in modulating ion channel abundance and membrane trafficking in neurons, thereby shaping their biophysical properties and function.

Filamin A (FLNA) profil antigène

Antigen Summary

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Filamin A (FLNA)

  • filamin A, alpha (actin binding protein 280) (flna) anticorps
  • filamin A, alpha (FLNA) anticorps
  • filamin B, like (flnbl) anticorps
  • filamin A, alpha (flna) anticorps
  • cheerio (cher) anticorps
  • filamin A, alpha (Flna) anticorps
  • filamin, alpha (Flna) anticorps
  • ABP-280 anticorps
  • ABPX anticorps
  • cb967 anticorps
  • CG3937 anticorps
  • Cher anticorps
  • CSBS anticorps
  • CVD1 anticorps
  • Dilp2 anticorps
  • Dmel\\CG3937 anticorps
  • F730004A14Rik anticorps
  • fb98b06 anticorps
  • Fil anticorps
  • filamin-1 anticorps
  • FLN anticorps
  • FLN-A anticorps
  • Fln1 anticorps
  • flna anticorps
  • FMD anticorps
  • joy anticorps
  • MGC147094 anticorps
  • MNS anticorps
  • NHBP anticorps
  • OPD anticorps
  • OPD1 anticorps
  • OPD2 anticorps
  • RGD1560614 anticorps
  • sko anticorps
  • wu:fb98b06 anticorps
  • wu:fd09g03 anticorps
  • wu:fd18g06 anticorps
  • wu:fd49a06 anticorps
  • XLVD anticorps
  • XMVD anticorps

Protein level used designations for anti-Filamin A, alpha (FLNA) Anticorps

fd09g03 , filamin A, alpha (actin binding protein 280) , filamin B, like , filamin A, alpha , filamin-A , CG3937-PA , CG3937-PB , CG3937-PF , CG3937-PG , CG3937-PH , CG3937-PI , CG3937-PK , CG3937-PL , CG3937-PM , CG3937-PN , Filamin-1 , Filamin-A , cher-PA , cher-PB , cher-PF , cher-PG , cher-PH , cher-PI , cher-PK , cher-PL , cher-PM , cher-PN , filamin , filamin B , filamin isoform B , filamin-240 , shi kong , actin binding protein 280 , alpha-filamin , endothelial actin-binding protein , filamin-1 , non-muscle filamin , Endothelial actin-binding protein 280) , filamin, alpha , 450 kDa protein , FLN-A , GENA 379 , actin-binding protein 280 , dilated pupils 2 , filamin A

GENE ID SPECIES
562529 Danio rerio
699524 Macaca mulatta
569979 Danio rerio
587317 Strongylocentrotus purpuratus
779840 Xenopus (Silurana) tropicalis
100137263 Papio anubis
42066 Drosophila melanogaster
100380643 Salmo salar
2316 Homo sapiens
293860 Rattus norvegicus
481084 Canis lupus familiaris
733585 Sus scrofa
281165 Bos taurus
100328754 Oryctolagus cuniculus
100725162 Cavia porcellus
395261 Gallus gallus
101120390 Ovis aries
192176 Mus musculus
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