Aperçu des produits pour anti-CD226 (CD226) Anticorps

Full name:
anti-CD226 Molecule Anticorps (CD226)
Chez www.anticorps-enligne.fr sont 210 CD226 Molecule (CD226) Anticorps de 22 de différents fournisseurs disponibles. De plus, nous expédions CD226 Protéines (24) et CD226 Kits (14) et beaucoup plus de produits pour cette protéine. Un total de 263 CD226 produits sont actuellement listés.
BC051526, cd226, DNAM-1, DNAM1, PTA1, TLiSA1, zgc:158817

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anti-Mouse (Murine) CD226 Anticorps:

anti-Human CD226 Anticorps:

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anti-CD226 Anticorps mieux référencés

  1. Human Monoclonal CD226 Primary Antibody pour Func, FACS - ABIN119797 : Kojima, Kanada, Shimizu, Kasama, Shibuya, Nakauchi, Nagasawa, Shibuya: CD226 mediates platelet and megakaryocytic cell adhesion to vascular endothelial cells. dans The Journal of biological chemistry 2003 (PubMed)
    Show all 3 references for 119797

  2. Human Monoclonal CD226 Primary Antibody pour FACS - ABIN119800 : Shibuya, Campbell, Hannum, Yssel, Franz-Bacon, McClanahan, Kitamura, Nicholl, Sutherland, Lanier, Phillips: DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes. dans Immunity 1996 (PubMed)
    Show all 3 references for 119800

  3. Human Monoclonal CD226 Primary Antibody pour FACS - ABIN119796 : Shibuya, Lanier, Phillips: Protein kinase C is involved in the regulation of both signaling and adhesion mediated by DNAX accessory molecule-1 receptor. dans Journal of immunology (Baltimore, Md. : 1950) 1998 (PubMed)
    Show all 3 references for 119796

  4. Human Monoclonal CD226 Primary Antibody pour FACS - ABIN4896039 : Liu, Qian, Chen, Xu, Gao, Zhang, Zhang, Qi, Gao, Yan: Crystal structure of cell adhesion molecule nectin-2/CD112 and its binding to immune receptor DNAM-1/CD226. dans Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)

  5. Human Monoclonal CD226 Primary Antibody pour FACS - ABIN4896040 : Brunetta, Fogli, Varchetta, Bozzo, Hudspeth, Marcenaro, Moretta, Mavilio: The decreased expression of Siglec-7 represents an early marker of dysfunctional natural killer-cell subsets associated with high levels of HIV-1 viremia. dans Blood 2009 (PubMed)

  6. Human Monoclonal CD226 Primary Antibody pour FACS - ABIN1449202 : Shibuya, Shirakawa, Kameyama, Honda, Tahara-Hanaoka, Miyamoto, Onodera, Sumida, Nakauchi, Miyoshi, Shibuya: CD226 (DNAM-1) is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferation. dans The Journal of experimental medicine 2003 (PubMed)

Plus d’anticorps contre CD226 partenaires d’interaction

Mouse (Murine) CD226 Molecule (CD226) interaction partners

  1. Blocking CD226 inhibited NK cell-mediated cytotoxicity of the GM-CSF (Montrer CSF2 Anticorps)-stimulated Flt3 ligand (Montrer FLT3LG Anticorps) conventional dendritic cells. The CD226(+)NKG2A (Montrer KLRC1 Anticorps)(-) subset of NK cells was better at targeting GM-CSF (Montrer CSF2 Anticorps)-stimulated Flt3 ligand (Montrer FLT3LG Anticorps) conventional dendritic cells. CD155 (Montrer PVR Anticorps), a known ligand for CD226, could also act as an inhibitor of NK cell-mediated lysis, as dendritic cells lacking CD155 (Montrer PVR Anticorps) were more sensitive to NK cell-mediated lysis.

  2. inflammatory monocytes, together with NK cells, are essential in the early control of CMV through the DNAM-1-PVR (Montrer PVRL2 Anticorps) pathway.

  3. Data show that CD155 (Montrer PVR Anticorps) protein/CD226 antigen mainly mediates the interaction between NK cells and leukemic cells in acute myeloid leukemia (Montrer BCL11A Anticorps). To investigate the interaction between leukemic cells

  4. absence of either CD155 (Montrer PVR Anticorps) or CD226 in BALB/c mice causes a profound shift in the Natural Killer T-Cells subtype composition in thymus, expanding the frequency and numbers of iNKT1 cells at the expense of iNKT2 cells, as well as iNKT17 cells.

  5. our results suggest a limited role for DNAM-1 in solid allograft rejection. Blocking DNAM-1 is not sufficient to prevent allograft rejection and might be relevant only in combination with additional inhibitors of costimulation.

  6. we propose that expression of DNAM-1 on inflammatory monocytes are evolutionally conserved and act as an adhesion molecule (Montrer NCAM1 Anticorps) on blood inflammatory monocytes.

  7. Data indicate that DNAM-1 (CD226) signaling was required to enhance cytotoxicity.

  8. Regulatory T cells derived (Montrer CD4 Anticorps)from Cd226-deficient mice showed similarly reduced inhibitory activity, eventually resulting in an exacerbated disease course of experimental autoimmune encephalomyelitis.

  9. CD226 limits spontaneous multiple myeloma development in Vk*MYC (Montrer MYC Anticorps) transgenic mice. This is mediated both by NK and CD8 (Montrer CD8A Anticorps)+ T cells through perforin (Montrer PRF1 Anticorps) and IFN-gamma (Montrer IFNG Anticorps) pathways. It also is needed for cyclophosphamide and bortezomib treatment effectiveness.

  10. Findings suggest that TIGIT (Montrer TIGIT Anticorps) is a key checkpoint inhibitor of chronic antiviral and antitumor responses through impairing CD226 function when disrupting its homodimerization.

Human CD226 Molecule (CD226) interaction partners

  1. cumulative incidences of acute graft-versus-host disease in patients with high maximal serum levels of sDNAM-1 (>/=30 pM) in the 7 days before allogeneic hematopoietic stem cell transplantation were significantly higher than those in patients with low maximal serum levels of sDNAM-1 in the same period. Our data suggest sDNAM-1 is potentially a unique candidate as a predictive biomarker for the development of acute GVHD.

  2. Our results support an important association of rs4810485 in CD40 (Montrer CD40 Anticorps) gene and rs763361 in CD226 gene polymorphism, combined effect of rs4810485 and rs763361 with increased risk of systemic lupus erythematosus.

  3. our results support and explain the mechanism behind the recently reported finding that in EOC, NK-cell recognition and killing of tumor cells was mainly dependent on DNAM-1 signaling while the contribution of the NKG2D (Montrer KLRK1 Anticorps) receptor-ligand pathway was complementary and uncertain.

  4. CD226 rs763361 polymorphism was significantly associated with susceptibility to T1D.

  5. Age and CMV serostatus influence the expression of NKp30 (Montrer NCR3 Anticorps), NKp46 (Montrer NCR1 Anticorps) and DNAM-1 activating receptors on resting and IL-2 (Montrer IL2 Anticorps) activated natural killer cells.

  6. we propose that expression of DNAM-1 on inflammatory monocytes are evolutionally conserved and act as an adhesion molecule (Montrer NCAM1 Anticorps) on blood inflammatory monocytes.

  7. DNAM-1 ligands CD112 (Montrer PVRL2 Anticorps) and CD155 (Montrer PVR Anticorps) as well as the NKG2D (Montrer KLRK1 Anticorps) ligands MICA (Montrer MICA Anticorps) and MICB (Montrer MICB Anticorps) were expressed on the hiPSC lines

  8. The CD226 gene has been identified as novel association with JIA, and a SNP near CD28 (Montrer CD28 Anticorps) as a suggestive association.

  9. Effector and regulatory CD4 (Montrer CD4 Anticorps)+ memory T cells of healthy individuals carrying the predisposing CD226 variant showed, in comparison to carriers of the protective variant, reduced surface expression of CD226 and impaired induction of CD226 after stimulation.

  10. The present study provides evidence that regulation of the PVR/CD155 (Montrer PVR Anticorps) DNAM-1 ligand expression by nitric oxide may represent an additional immune-mediated mechanism and supports the anti-myeloma activity of nitric oxide donors.

CD226 profil antigène

Antigen Summary

This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation.

Alternative names and synonyms associated with CD226

  • CD226 molecule (CD226) anticorps
  • CD226 antigen (cd226) anticorps
  • CD226 molecule (cd226) anticorps
  • CD226 antigen (Cd226) anticorps
  • CD226 molecule (Cd226) anticorps
  • BC051526 anticorps
  • cd226 anticorps
  • DNAM-1 anticorps
  • DNAM1 anticorps
  • PTA1 anticorps
  • TLiSA1 anticorps
  • zgc:158817 anticorps

Protein level used designations for anti-CD226 Molecule (CD226) Anticorps

CD226 antigen , CD226 molecule , platelet and T cell activation antigen 1 , platelet and T-cell activation antigen 1 , DNAX accessory molecule 1 , DNAX accessory molecule-1 , T lineage-specific activation antigen 1 antigen , adhesion glycoprotein

468577 Pan troglodytes
609196 Canis lupus familiaris
100194885 Salmo salar
791164 Danio rerio
772097 Gallus gallus
100579250 Nomascus leucogenys
225825 Mus musculus
10666 Homo sapiens
615496 Bos taurus
307199 Rattus norvegicus
703878 Macaca mulatta
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