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Aperçu des produits pour anti-CD226 (CD226) Anticorps

Full name:
anti-CD226 Molecule Anticorps (CD226)
Chez sont 197 CD226 Molecule (CD226) Anticorps de 21 de différents fournisseurs disponibles. De plus, nous expédions CD226 Protéines (21) et CD226 Kits (12) et beaucoup plus de produits pour cette protéine. Un total de 246 CD226 produits sont actuellement listés.
BC051526, cd226, DNAM-1, DNAM1, PTA1, TLiSA1, zgc:158817

Réactivités les plus populaires pour anti-CD226 (CD226) Anticorps

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anti-Mouse (Murine) CD226 Anticorps:

anti-Human CD226 Anticorps:

anti-Rat (Rattus) CD226 Anticorps:

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anti-CD226 Anticorps mieux référencés

  1. Human Monoclonal CD226 Primary Antibody pour Func, FACS - ABIN119797 : Kojima, Kanada, Shimizu, Kasama, Shibuya, Nakauchi, Nagasawa, Shibuya: CD226 mediates platelet and megakaryocytic cell adhesion to vascular endothelial cells. dans The Journal of biological chemistry 2003 (PubMed)
    Show all 3 references for ABIN119797

  2. Human Monoclonal CD226 Primary Antibody pour FACS - ABIN119800 : Shibuya, Campbell, Hannum, Yssel, Franz-Bacon, McClanahan, Kitamura, Nicholl, Sutherland, Lanier, Phillips: DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes. dans Immunity 1996 (PubMed)
    Show all 3 references for ABIN119800

  3. Human Monoclonal CD226 Primary Antibody pour FACS - ABIN119796 : Shibuya, Lanier, Phillips: Protein kinase C is involved in the regulation of both signaling and adhesion mediated by DNAX accessory molecule-1 receptor. dans Journal of immunology (Baltimore, Md. : 1950) 1998 (PubMed)
    Show all 3 references for ABIN119796

  4. Human Monoclonal CD226 Primary Antibody pour FACS - ABIN4896039 : Liu, Qian, Chen, Xu, Gao, Zhang, Zhang, Qi, Gao, Yan: Crystal structure of cell adhesion molecule nectin-2/CD112 and its binding to immune receptor DNAM-1/CD226. dans Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)

  5. Human Monoclonal CD226 Primary Antibody pour FACS, Neut - ABIN4899392 : Magnani, Alberigo, Bacchetta, Serafini, Andreani, Roncarolo, Gregori: Killing of myeloid APCs via HLA class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells. dans European journal of immunology 2011 (PubMed)

  6. Human Monoclonal CD226 Primary Antibody pour FACS - ABIN1449202 : Shibuya, Shirakawa, Kameyama, Honda, Tahara-Hanaoka, Miyamoto, Onodera, Sumida, Nakauchi, Miyoshi, Shibuya: CD226 (DNAM-1) is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferation. dans The Journal of experimental medicine 2003 (PubMed)

Plus d’anticorps contre CD226 partenaires d’interaction

Mouse (Murine) CD226 Molecule (CD226) interaction partners

  1. Data show that CD155 (Montrer PVR Anticorps) protein/CD226 antigen mainly mediates the interaction between NK cells and leukemic cells in acute myeloid leukemia (Montrer BCL11A Anticorps). To investigate the interaction between leukemic cells

  2. absence of either CD155 (Montrer PVR Anticorps) or CD226 in BALB/c mice causes a profound shift in the Natural Killer T-Cells subtype composition in thymus, expanding the frequency and numbers of iNKT1 cells at the expense of iNKT2 cells, as well as iNKT17 cells.

  3. our results suggest a limited role for DNAM-1 in solid allograft rejection. Blocking DNAM-1 is not sufficient to prevent allograft rejection and might be relevant only in combination with additional inhibitors of costimulation.

  4. we propose that expression of DNAM-1 on inflammatory monocytes are evolutionally conserved and act as an adhesion molecule (Montrer NCAM1 Anticorps) on blood inflammatory monocytes.

  5. Data indicate that DNAM-1 (CD226) signaling was required to enhance cytotoxicity.

  6. Regulatory T cells derived (Montrer CD4 Anticorps)from Cd226-deficient mice showed similarly reduced inhibitory activity, eventually resulting in an exacerbated disease course of experimental autoimmune encephalomyelitis.

  7. CD226 limits spontaneous multiple myeloma development in Vk*MYC (Montrer MYC Anticorps) transgenic mice. This is mediated both by NK and CD8 (Montrer CD8A Anticorps)+ T cells through perforin (Montrer PRF1 Anticorps) and IFN-gamma (Montrer IFNG Anticorps) pathways. It also is needed for cyclophosphamide and bortezomib treatment effectiveness.

  8. Findings suggest that TIGIT (Montrer TIGIT Anticorps) is a key checkpoint inhibitor of chronic antiviral and antitumor responses through impairing CD226 function when disrupting its homodimerization.

  9. This synapse defect may explain why DNAM-1-deficient mice cannot clear tumors in vivo.

  10. cooperative signaling through DNAM-1 and Ly49H (Montrer KLRA8 Anticorps) are required for NK cell-mediated host defense against MCMV infection

Human CD226 Molecule (CD226) interaction partners

  1. our results support and explain the mechanism behind the recently reported finding that in EOC, NK-cell recognition and killing of tumor cells was mainly dependent on DNAM-1 signaling while the contribution of the NKG2D (Montrer KLRK1 Anticorps) receptor-ligand pathway was complementary and uncertain.

  2. CD226 rs763361 polymorphism was significantly associated with susceptibility to T1D.

  3. Age and CMV serostatus influence the expression of NKp30 (Montrer NCR3 Anticorps), NKp46 (Montrer NCR1 Anticorps) and DNAM-1 activating receptors on resting and IL-2 (Montrer IL2 Anticorps) activated natural killer cells.

  4. we propose that expression of DNAM-1 on inflammatory monocytes are evolutionally conserved and act as an adhesion molecule (Montrer NCAM1 Anticorps) on blood inflammatory monocytes.

  5. DNAM-1 ligands CD112 (Montrer PVRL2 Anticorps) and CD155 (Montrer PVR Anticorps) as well as the NKG2D (Montrer KLRK1 Anticorps) ligands MICA (Montrer MICA Anticorps) and MICB (Montrer MICB Anticorps) were expressed on the hiPSC lines

  6. The CD226 gene has been identified as novel association with JIA, and a SNP near CD28 (Montrer CD28 Anticorps) as a suggestive association.

  7. Effector and regulatory CD4 (Montrer CD4 Anticorps)+ memory T cells of healthy individuals carrying the predisposing CD226 variant showed, in comparison to carriers of the protective variant, reduced surface expression of CD226 and impaired induction of CD226 after stimulation.

  8. The present study provides evidence that regulation of the PVR/CD155 (Montrer PVR Anticorps) DNAM-1 ligand expression by nitric oxide may represent an additional immune-mediated mechanism and supports the anti-myeloma activity of nitric oxide donors.

  9. our data reveal the existence of a functional program of NK cell maturation marked by DNAM-1 expression.

  10. upregulated CD226 expression on CD8 (Montrer CD8A Anticorps)(+) T cells reflects disease severity and is involved in Systemic sclerosis pathogenesis via the production of various cytokines, including profibrotic IL-13 (Montrer IL13 Anticorps) and endothelial cell injury

CD226 profil antigène

Antigen Summary

This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation.

Alternative names and synonyms associated with CD226

  • CD226 molecule (CD226) anticorps
  • CD226 antigen (cd226) anticorps
  • CD226 molecule (cd226) anticorps
  • CD226 antigen (Cd226) anticorps
  • CD226 molecule (Cd226) anticorps
  • BC051526 anticorps
  • cd226 anticorps
  • DNAM-1 anticorps
  • DNAM1 anticorps
  • PTA1 anticorps
  • TLiSA1 anticorps
  • zgc:158817 anticorps

Protein level used designations for anti-CD226 Molecule (CD226) Anticorps

CD226 antigen , CD226 molecule , platelet and T cell activation antigen 1 , platelet and T-cell activation antigen 1 , DNAX accessory molecule 1 , DNAX accessory molecule-1 , T lineage-specific activation antigen 1 antigen , adhesion glycoprotein

468577 Pan troglodytes
609196 Canis lupus familiaris
100194885 Salmo salar
791164 Danio rerio
772097 Gallus gallus
100579250 Nomascus leucogenys
225825 Mus musculus
10666 Homo sapiens
615496 Bos taurus
307199 Rattus norvegicus
703878 Macaca mulatta
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