Aperçu des produits pour anti-BAD (BAD) Anticorps

Full name:
anti-BCL2-Associated Agonist of Cell Death Anticorps (BAD)
Chez www.anticorps-enligne.fr sont 993 BCL2-Associated Agonist of Cell Death (BAD) Anticorps de 32 de différents fournisseurs disponibles. De plus, nous expédions BAD Kits (52) et BAD Protéines (11) et beaucoup plus de produits pour cette protéine. Un total de 1132 BAD produits sont actuellement listés.
AI325008, BAD, Bbc2, BCL2L8, fa01b12, wu:fa01b12, wu:fa96d04

Réactivités les plus populaires pour anti-BAD (BAD) Anticorps

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anti-Human BAD Anticorps:

anti-Mouse (Murine) BAD Anticorps:

anti-Rat (Rattus) BAD Anticorps:

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anti-BAD Anticorps mieux référencés

  1. Human Polyclonal BAD Primary Antibody pour EIA, IHC (p) - ABIN358087 : Hurbin, Coll, Dubrez-Daloz, Mari, Auberger, Brambilla, Favrot: Cooperation of amphiregulin and insulin-like growth factor-1 inhibits Bax- and Bad-mediated apoptosis via a protein kinase C-dependent pathway in non-small cell lung cancer cells. dans The Journal of biological chemistry 2005 (PubMed)
    Show all 5 references for 358087

  2. Human Polyclonal BAD Primary Antibody pour FACS, IHC (p) - ABIN388118 : Won, Kim, La, Kim, Meadows, Joe: Cleavage of 14-3-3 protein by caspase-3 facilitates bad interaction with Bcl-x(L) during apoptosis. dans The Journal of biological chemistry 2003 (PubMed)
    Show all 3 references for 388118

  3. Human Polyclonal BAD Primary Antibody pour IHC (p), WB - ABIN389520 : Antignani, Youle: A chimeric protein induces tumor cell apoptosis by delivering the human Bcl-2 family BH3-only protein Bad. dans Biochemistry 2005 (PubMed)
    Show all 2 references for 389520

  4. Human Polyclonal BAD Primary Antibody pour IF, IHC - ABIN1531524 : Wang, Rapp, Reed: Bcl-2 targets the protein kinase Raf-1 to mitochondria. dans Cell 1997 (PubMed)

  5. Cow (Bovine) Polyclonal BAD Primary Antibody pour WB - ABIN2779324 : Xia, Zhang, Du, Pan, Zhao, Sun, Hong, Liu, Fan: miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. dans International journal of cancer. Journal international du cancer 2008 (PubMed)

Plus d’anticorps contre BAD partenaires d’interaction

Zebrafish BCL2-Associated Agonist of Cell Death (BAD) interaction partners

  1. Bad functions as an essential sensitizer and Puma (Montrer BBC3 Anticorps) as an essential activator of IR-induced mitochondrial apoptosis specifically in embryonic neural tissue.

  2. Stage-specific expression of TNFalpha (Montrer TNF Anticorps) regulates bad/bid (Montrer BID Anticorps)-mediated apoptosis and RIP1 (Montrer RALBP1 Anticorps)/ROS (Montrer ROS1 Anticorps)-mediated secondary necrosis in Birnavirus-infected fish cells.

  3. Results indicate that zebrafish BH3-only (Montrer BBC3 Anticorps) proapoptotic protein (BAD) could induce apoptosis in vitro and in vivo and may have biological implications in apoptosis during zebrafish development.

Human BCL2-Associated Agonist of Cell Death (BAD) interaction partners

  1. The long unstructured region of Bcl-xl (Montrer BCL2L1 Anticorps) modulates its structural dynamics.

  2. Short-term treatment of nascent melanoma tumors with PAK inhibitors that block RhoJ (Montrer RHOJ Anticorps) signaling halts the growth of BRAF (Montrer BRAF Anticorps) mutant melanoma tumors in vivo and induces apoptosis in melanoma cells in vitro via a BAD-dependent mechanism. As up to 50% of BRAF (Montrer BRAF Anticorps) mutant human melanomas express high levels of RhoJ (Montrer RHOJ Anticorps), these studies nominate the RhoJ (Montrer RHOJ Anticorps)-BAD signaling network as a therapeutic vulnerability for fledgling BRAF (Montrer BRAF Anticorps) mutant human tumor

  3. Recent studies that combine experiments in yeast and in mammalian cells have shown the unexpected effect of the anti-apoptotic protein Bcl-xL (Montrer BCL2L1 Anticorps) on the priming of Bax (Montrer BAX Anticorps). As demonstrated with the BH3-mimetic molecule ABT-737, this property of Bcl-xL (Montrer BCL2L1 Anticorps), and of Bcl-2 (Montrer BCL2 Anticorps), is crucial to elaborate about how apoptosis could be reactivated in tumoral cells.

  4. the accumulation of reactive oxygen species (ROS (Montrer ROS1 Anticorps)) in cells expressing JAK2V617F compromises the NHE-1 (Montrer SLC9A1 Anticorps)/Bcl-xL (Montrer BCL2L1 Anticorps) deamidation pathway by repressing NHE-1 (Montrer SLC9A1 Anticorps) upregulation in response to DNA damage. hematopoietic stem cells (HSCs), FOXO3A (Montrer FOXO3 Anticorps) is largely localized within the nuclei despite the presence of JAK2V617F mutation, suggesting that JAK2 (Montrer JAK2 Anticorps)-FOXO (Montrer FOXO3 Anticorps) signaling has a different effect on progenitors compared with stem cells.

  5. These results identify beta3 integrin (Montrer ITGB3 Anticorps) signaling via repression of BAD as an important survival pathway used by breast cancer cells to evade chemotherapy induced stress.

  6. miR (Montrer MLXIP Anticorps)-377 was markedly downregulated in HCC (Montrer FAM126A Anticorps) cell lines and primary human HCC (Montrer FAM126A Anticorps) tissues. The decreased expression of miR (Montrer MLXIP Anticorps)-377 contributes to the upregulation of Bcl-xL (Montrer BCL2L1 Anticorps) expression by targeting its 3'-untranslated region (3'-UTR (Montrer UTS2R Anticorps)).

  7. By the pharmacologic targeting of BCL2 (Montrer BCL2 Anticorps), MCL1 (Montrer MCL1 Anticorps), and BCL-XL (Montrer BCL2L1 Anticorps), we demonstrated that diffuse large B-cell lymphoma can be divided into BCL2 (Montrer BCL2 Anticorps)-dependent and MCL1 (Montrer MCL1 Anticorps)-dependent subgroups with a less pronounced role left for BCL-XL (Montrer BCL2L1 Anticorps).

  8. increased platelet apoptosis and activation as well as reduced expression of Bcl-xL (Montrer BCL2L1 Anticorps), increased expression of Bax (Montrer BAX Anticorps) and caspase-3 (Montrer CASP3 Anticorps) activity were found in platelets after treated with ITP (Montrer ITPA Anticorps) plasma in comparison with control plasma.

  9. These findings demonstrated that Akt (Montrer AKT1 Anticorps) is related to NF-kappaB (Montrer NFKB1 Anticorps) and Bad signaling pathway possibly playing a direct role in the progression of liver cancer. Thus, Akt (Montrer AKT1 Anticorps) might be an important and potential treatment choice for the clinical diagnosis and treatment in the future.

  10. Bh3 domain induced conformational changes in Bcl-Xl (Montrer BCL2L1 Anticorps) revealed by crystal structure and comparative analysis.

Mouse (Murine) BCL2-Associated Agonist of Cell Death (BAD) interaction partners

  1. Bad is dispensable for TNF (Montrer TNF Anticorps)-mediated cell death.

  2. Results indicate the downstream targets of insulin (Montrer INS Anticorps), cyclin D1 (Montrer CCND1 Anticorps), BAD, alpha-MHC (Montrer MYH6 Anticorps), and GATA-4 (Montrer GATA4 Anticorps), elucidate a molecular mechanism of insulin (Montrer INS Anticorps) in promoting cell proliferation and differentiation.

  3. our study suggests that Bad and Bmf (Montrer BMF Anticorps) co-regulate lymphocyte homeostasis and limit spontaneous transformation by mechanisms that may not exclusively be linked to the induction of lymphocyte apoptosis.

  4. Results reveal that IKK (Montrer CHUK Anticorps) inhibits TNFalpha (Montrer TNF Anticorps)-induced apoptosis through two distinct but cooperative mechanisms: activation of the survival factor NF-kappaB (Montrer NFKB1 Anticorps) and inactivation of the proapoptotic BH3-only (Montrer BBC3 Anticorps) BAD protein.

  5. RNAi-mediated silencing of STAT1 (Montrer STAT1 Anticorps) in soft tissue sarcoma (STS (Montrer STS Anticorps)) cells was sufficient to increase expression of the apoptotic mediators Fas (Montrer FAS Anticorps) and Bad and to elevate the sensitivity of STS (Montrer STS Anticorps) cells to Fas (Montrer FAS Anticorps)-mediated apoptosis

  6. Tonicity-induced COX-2 (Montrer COX2 Anticorps) expression and PGE2 synthesis in the renal medulla entails phosphorylation and inactivation of the pro-apoptotic protein Bad, thereby counteracting apoptosis in renal medullary epithelial cells.

  7. Caspase-3 (Montrer CASP3 Anticorps) is activated by the BAD-BAX (Montrer BAX Anticorps) cascade resulting in long term depression induction in the hippocampus.

  8. JNK1 (Montrer MAPK8 Anticorps) is required for erythropoietin (Montrer EPO Anticorps)-mediated cell survival through phosphorylation and inactivation of the pro-apoptotic, Bcl-2 (Montrer BCL2 Anticorps) homology domain 3 (BH3)-only (Montrer BBC3 Anticorps) Bcl-associated death protein (Bad).

  9. Bad protein cooperate with bim (Montrer BCL2L11 Anticorps) protein in certain apoptotic responses and in the suppression of g-irradiation-induced thymic lymphoma.(Bad protein)

  10. Data show that loss of Bmf (Montrer BMF Anticorps) reduced the pressure to inactivate p53 (Montrer TP53 Anticorps), whereas Bad deficiency did not, identifying Bmf (Montrer BMF Anticorps) as a novel component of the p53 (Montrer TP53 Anticorps)-independent tumor suppressor pathway triggered by c-Myc (Montrer MYC Anticorps).

Cow (Bovine) BCL2-Associated Agonist of Cell Death (BAD) interaction partners

BAD profil antigène

Antigen Summary

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Alternative names and synonyms associated with BAD

  • BCL2-antagonist of cell death b (badb) anticorps
  • BCL2-associated agonist of cell death (BAD) anticorps
  • BCL2-associated agonist of cell death (Bad) anticorps
  • AI325008 anticorps
  • BAD anticorps
  • Bbc2 anticorps
  • BCL2L8 anticorps
  • fa01b12 anticorps
  • wu:fa01b12 anticorps
  • wu:fa96d04 anticorps

Protein level used designations for BAD

proapoptotic BH3-only protein , BCL2-antagonist of cell death , BCL2-associated agonist of cell death , BCL-X/BCL-2 binding protein , BCL2-antagonist of cell death protein , BCL2-binding component 6 , BCL2-binding protein , bcl-2-binding component 6 , bcl-2-like protein 8 , bcl-XL/Bcl-2-associated death promoter , bcl2 antagonist of cell death , bcl2-L-8 , Bcl-associated death promoter , bcl-xL/Bcl-2-associated death promoter , Bcl2-antagonist of cell death , bcl-2 associated death agonist , bcl2-associated death promoter

58100 Danio rerio
768269 Felis catus
780444 Ovis aries
572 Homo sapiens
12015 Mus musculus
64639 Rattus norvegicus
483763 Canis lupus familiaris
615013 Bos taurus
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