Aperçu des produits pour anti-MAP3K5 (MAP3K5) Anticorps

Full name:
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 Anticorps (MAP3K5)
Chez www.anticorps-enligne.fr sont 389 Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) Anticorps de 29 de différents fournisseurs disponibles. De plus, nous expédions MAP3K5 Kits (39) et MAP3K5 Protéines (12) et beaucoup plus de produits pour cette protéine. Un total de 467 MAP3K5 produits sont actuellement listés.
Synonymes:
7420452D20Rik, ASK, ASK1, MAP3K5, MAPKKK5, MEKK5, mitogen-activated protein kinase kinase kinase 5, MUD21.11, MUD21_11

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anti-MAP3K5 Anticorps mieux référencés

  1. Human Polyclonal MAP3K5 Primary Antibody pour WB - ABIN116930 : Matsuzawa, Ichijo: Molecular mechanisms of the decision between life and death: regulation of apoptosis by apoptosis signal-regulating kinase 1. dans Journal of biochemistry 2001 (PubMed)
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  2. Human Monoclonal MAP3K5 Primary Antibody pour IF, WB - ABIN393594 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. dans Diabetes Care 2010 (PubMed)
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  3. Human Polyclonal MAP3K5 Primary Antibody pour IF, IHC (p) - ABIN197326 : Zhang, Zheng, Storz, Min: Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor. dans The Journal of biological chemistry 2005 (PubMed)
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  4. Human Polyclonal MAP3K5 Primary Antibody pour IHC (p), WB - ABIN196914 : Fujii, Goldman, Park, Zhang, Chen, Fu: Negative control of apoptosis signal-regulating kinase 1 through phosphorylation of Ser-1034. dans Oncogene 2004 (PubMed)
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  5. Human Polyclonal MAP3K5 Primary Antibody pour IF, IHC (p) - ABIN197310 : Mabuchi, Ohmichi, Kimura, Nishio, Arimoto-Ishida, Yada-Hashimoto, Tasaka, Murata: Estrogen inhibits paclitaxel-induced apoptosis via the phosphorylation of apoptosis signal-regulating kinase 1 in human ovarian cancer cell lines. dans Endocrinology 2003 (PubMed)
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  6. Human Polyclonal MAP3K5 Primary Antibody pour IHC, ELISA - ABIN1531773 : Ichijo, Nishida, Irie, ten Dijke, Saitoh, Moriguchi, Takagi, Matsumoto, Miyazono, Gotoh: Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. dans Science (New York, N.Y.) 1997 (PubMed)
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  7. Human Polyclonal MAP3K5 Primary Antibody pour IHC (p), WB - ABIN196912 : Yuan, Feldman, Sussman, Coppola, Nicosia, Cheng: AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance. dans The Journal of biological chemistry 2003 (PubMed)
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  8. Human Polyclonal MAP3K5 Primary Antibody pour IHC, ELISA - ABIN1532802 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... dans Nature 2003 (PubMed)
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  9. Human Polyclonal MAP3K5 Primary Antibody pour IF (p), IHC (p) - ABIN683128 : Taniuchi, Furihata, Hanazaki, Iwasaki, Tanaka, Shimizu, Saito, Saibara: Peroxiredoxin 1 Promotes Pancreatic Cancer Cell Invasion by Modulating p38 MAPK Activity. dans Pancreas 2015 (PubMed)

Plus d’anticorps contre MAP3K5 partenaires d’interaction

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) interaction partners

  1. These results suggest that the platelet Ask1 plays an important role in regulation of hemostasis and thrombosis.

  2. Lysine 29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response.

  3. These results demonstrate that trans-fatty acids promote extracellular ATP-induced apoptosis by targeting ASK1 and indicate novel TFA (Montrer F3 Anticorps)-associated pathways leading to inflammatory signal transduction and cell death that underlie the pathogenesis and progression of trans-fatty acids-induced atherosclerosis.

  4. Conversely, treatment with LY294002 (a selective inhibitor of Akt1 (Montrer AKT1 Anticorps)) reversed the effects of quercetin. In conclusion, these findings highlight the important role of quercetin in protecting against cognitive deficits and inhibiting neuronal apoptosis via the Akt (Montrer AKT1 Anticorps) signaling pathway. We believe that quercetin might prove to be a useful therapeutic component in treating cerebral I/R diseases in the near future.

  5. ASK1 MAP kinase (Montrer MAPK1 Anticorps) signaling cascade is an important regulator of chondrocyte terminal differentiation.

  6. ASK1 mediates astrocyte activation and leads to glial scar formation after cerebral ischaemia.

  7. ASK1 mediates 3-NP toxicity and regulates C1q level through the astrocyte TGF-beta (Montrer TGFB1 Anticorps).

  8. ASK1 signalling regulates brown and beige (Montrer LYST Anticorps) adipocyte function.

  9. blocking MPTP (Montrer PTPN2 Anticorps)-mediated TNF (Montrer TNF Anticorps) signaling through intrathecal administration of TNF (Montrer TNF Anticorps)-neutralizing antibody prevented Trx1 (Montrer TXN Anticorps) oxidation and downstream ASK1-p38 MAPK (Montrer MAPK14 Anticorps) activation

  10. ASK1 deletion in vivo significantly suppresses hyperoxia-induced elevation of inflammatory cytokines (i.e. IL-1beta (Montrer IL1B Anticorps) and TNF-alpha (Montrer TNF Anticorps)), cell apoptosis in the lung, and recruitment of immune cells

Arabidopsis thaliana Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) interaction partners

  1. PBL27 interacts with both CERK1 and the MAPK (Montrer MAPK1 Anticorps) kinase kinase MAPKKK5 at the plasma membrane and knockout of MAPKKK5 compromise chitin-induced MAPK (Montrer MAPK1 Anticorps) kinase activation and disease resistance to Alternaria brassicicola.

Human Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) interaction partners

  1. CD40 (Montrer CD40 Anticorps) activation resulted in down-regulation of Thioredoxin (Trx)-1 (Montrer TXN Anticorps) to permit ASK1 activation and apoptosis. Although soluble receptor (Montrer IFNAR1 Anticorps) agonist alone could not induce death, combinatorial treatment incorporating soluble CD40 (Montrer CD40 Anticorps) agonist and pharmacological inhibition of Trx-1 (Montrer MLL Anticorps) was functionally equivalent to the signal triggered by mCD40L

  2. These results suggest that the platelet Ask1 plays an important role in regulation of hemostasis and thrombosis.

  3. from the two catalytic cysteines of TRX1 (Montrer MLL Anticorps) the residue C32 (Montrer CKLF Anticorps) is responsible for the high-affinity binding of TRX1 (Montrer MLL Anticorps) to the ASK1-TRX (Montrer VAC14 Anticorps)-binding domain in reducing conditions

  4. Shotgun mass spectrometry and manual validation identified 12 distinct ASK1 phosphosites. Targeted parallel reaction monitoring assays were used to track the phosphorylation dynamics of each confirmed site in response to treatment.

  5. phosphorus NMR and time-resolved tryptophan fluorescence measurements suggest that 14-3-3zeta (Montrer YWHAZ Anticorps) interacts with the kinase domain of ASK1 in close proximity to its active site, thus indicating this interaction might block its accessibility and/or affect its conformation.

  6. ASK1 MAP kinase (Montrer MAPK1 Anticorps) signaling cascade is an important regulator of chondrocyte terminal differentiation.

  7. Pretreatment by IRE1 (Montrer ERN1 Anticorps) agonist tunicamycin or JNK (Montrer MAPK8 Anticorps) agonist anisomycin attenuated the effect of psoralen on osteoporotic osteoblasts. Psoralen inhibited apoptosis of osteoporotic osteoblasts by regulating IRE1 (Montrer ERN1 Anticorps)-ASK1-JNK (Montrer MAPK8 Anticorps) pathway

  8. Our results thus suggest that GSK-3beta (Montrer GSK3b Anticorps) is a key factor involved in ASK1 activation and reactive oxygen species-induced cell death.

  9. the data show that miRNA-mediated down-regulation of ASK1 protects mesenchymal stem cells during post-transplantation, leading to an increase in the efficacy of MSC (Montrer MSC Anticorps)-based cell therapy.

  10. Cross-talk between arginine methylation and serine phosphorylation in ASK1.PRMT5 (Montrer PRMT5 Anticorps) is an ASK1-binding protein.PRMT5 mediates arginine methylation of ASK1.

MAP3K5 profil antigène

Antigen Summary

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells\; MAPKKK5 does not activate MAPK/ERK.

Alternative names and synonyms associated with MAP3K5

  • mitogen-activated protein kinase kinase kinase 5 (Map3k5) anticorps
  • mitogen-activated protein kinase kinase kinase 5 (MAPKKK5) anticorps
  • mitogen-activated protein kinase kinase kinase 5 (MAP3K5) anticorps
  • 7420452D20Rik anticorps
  • ASK anticorps
  • ASK1 anticorps
  • MAP3K5 anticorps
  • MAPKKK5 anticorps
  • MEKK5 anticorps
  • mitogen-activated protein kinase kinase kinase 5 anticorps
  • MUD21.11 anticorps
  • MUD21_11 anticorps

Protein level used designations for MAP3K5

ASK-1 , MAPK/ERK kinase kinase 5 , MEK kinase 5 , MEKK 5 , apoptosis signal-regulating kinase 1 , mitogen activated protein kinase kinase kinase 5 , MAP/ERK kinase kinase 5 , apoptosis signal regulating kinase 1 , mitogen-activated protein kinase kinase kinase 5

GENE ID SPECIES
293015 Mus musculus
836819 Arabidopsis thaliana
4217 Homo sapiens
26408 Mus musculus
100157454 Sus scrofa
537380 Bos taurus
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