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Aperçu des produits pour anti-GTPase NRas (NRAS) Anticorps

Full name:
anti-GTPase NRas Anticorps (NRAS)
Chez www.anticorps-enligne.fr sont 102 GTPase NRas (NRAS) Anticorps de 17 de différents fournisseurs disponibles. De plus, nous expédions GTPase NRas Protéines (18) et GTPase NRas Kits (6) et beaucoup plus de produits pour cette protéine. Un total de 131 GTPase NRas produits sont actuellement listés.
Synonymes:
ALPS4, AV095280, fj99a10, H-RAS, HRAS, N-RAS, NRAS, NRAS1, NS6, wu:fj99a10, zgc:100761, zras-b1

Réactivités les plus populaires pour anti-GTPase NRas (NRAS) Anticorps

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anti-Rat (Rattus) GTPase NRas Anticorps:

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anti-GTPase NRas Anticorps mieux référencés

  1. Human Monoclonal GTPase NRas Primary Antibody pour EIA, WB - ABIN781533 : Rocks, Peyker, Bastiaens: Spatio-temporal segregation of Ras signals: one ship, three anchors, many harbors. dans Current opinion in cell biology 2006 (PubMed)
    Show all 3 references for ABIN781533

  2. Human Polyclonal GTPase NRas Primary Antibody pour EIA, IHC (p) - ABIN360039 : Smalley, Contractor, Nguyen, Xiao, Edwards, Muthusamy, King, Flaherty, Bosenberg, Herlyn, Nathanson: Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression. dans Cancer research 2008 (PubMed)
    Show all 2 references for ABIN360039

  3. Human Polyclonal GTPase NRas Primary Antibody pour EIA, FACS - ABIN360038 : Banerji, Affolter, Judson, Marais, Workman: BRAF and NRAS mutations in melanoma: potential relationships to clinical response to HSP90 inhibitors. dans Molecular cancer therapeutics 2008 (PubMed)
    Show all 2 references for ABIN360038

  4. Human Polyclonal GTPase NRas Primary Antibody pour IHC (p), IHC - ABIN409077 : Thomas, Edmiston, Alexander, Millikan, Groben, Hao, Tolbert, Berwick, Busam, Begg, Mattingly, Ollila, Tse, Hummer, Lee-Taylor, Conway: Number of nevi and early-life ambient UV exposure are associated with BRAF-mutant melanoma. dans Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007 (PubMed)

  5. Human Monoclonal GTPase NRas Primary Antibody pour WB - ABIN1882272 : Hall, Brown: Human N-ras: cDNA cloning and gene structure. dans Nucleic acids research 1985 (PubMed)

Plus d’anticorps contre GTPase NRas partenaires d’interaction

Mouse (Murine) GTPase NRas (NRAS) interaction partners

  1. Genetic inactivation of Ezh2 (Montrer EZH2 Anticorps) or Eed (Montrer EED Anticorps) cooperates with NRASQ61K in leukemogenesis.

  2. Data indicate that S-phase kinase-associated protein 2 (SKP2) cooperates with N-Ras and AKT proto-oncogenes to promote hepatocarcinogenesis in vivo.

  3. Activated NRAS and aberrant Wnt (Montrer WNT2 Anticorps) signaling conspire to drive congenital melanocytic nevus syndrome.

  4. a crucial role of RXRa (Montrer RXRA Anticorps) in suppression of UVB-induced melanomas in the context of driver mutations such as activated CDK4 (Montrer CDK4 Anticorps)(R24C/R24C) or oncogenic NRAS(Q61K) and altered expression of p53 (Montrer TP53 Anticorps) and PTEN (Montrer PTEN Anticorps)

  5. This work explains the curious predominance in human melanoma of mutations of codon 61 of NRAS over other oncogenic NRAS mutations. we show that physiologic expression of NRASQ61R, but not NRASG12D, drives melanoma formation.

  6. These data reveal the L. major-enhanced CD40-induced N-Ras activation as a novel immune evasion strategy and the potential for Ras isoform-targeted antileishmanial immunotherapy and immunoprophylaxis.

  7. NRAS expression is required for the proliferative advantage of human AML (Montrer RUNX1 Anticorps) cell lines in vitro and for the maintenance of mouse Nras-mutant AML (Montrer RUNX1 Anticorps) in vivo

  8. There was a nearly complete correspondence between the signaling pathways that were regulated by N-ras in immune cell types.

  9. Cbfbeta (Montrer CBFB Anticorps)-SMMHC (Montrer MYH11 Anticorps) and Nras(G12D) promote the survival of preleukemic myeloid progenitors primed for leukemia by activation of the MEK (Montrer MDK Anticorps)/ERK (Montrer EPHB2 Anticorps)/Bim (Montrer BCL2L11 Anticorps) axis, and define Nras(LSL-G12D); Cbfb (Montrer CBFB Anticorps)(56M) mice as a valuable genetic model for the study of AML (Montrer RUNX1 Anticorps) therapies.

  10. regulation of Nf1 exon 23a inclusion serves as a mechanism for providing appropriate levels of Ras signaling.

Human GTPase NRas (NRAS) interaction partners

  1. NRAS mutation is associated with metastatic melanoma.

  2. The BRAF (Montrer BRAF Anticorps) was mutated in 55% (29/53) and NRAS in 11% (5/45) of the primary melanomas sequenced.

  3. Her-2 (Montrer ERBB2 Anticorps), N-ras and Nf1 (Montrer NF1 Anticorps) have roles in brain onocogenesis

  4. High NRAS expression is associated with hepatocellular carcinoma.

  5. Rare mutations in KRAS, NRAS, and BRAF (Montrer BRAF Anticorps) oncogenes have been found in patients with melanoma and colorectal neoplasms.

  6. NRAS and BRAF (Montrer BRAF Anticorps) mutations are independent events and alternative molecular mechanisms in the primary oral mucosal melanoma tumorigenesis

  7. NRAS gene mutations are associated with Urinary Bladder Cancer.

  8. Driver mutations are rare in mutational hotspots of BRAF (Montrer BRAF Anticorps), NRAS, KIT, and GNAQ (Montrer GNAQ Anticorps)/GNA11 (Montrer GNA11 Anticorps) in oral mucosal melanoma.

  9. NRAS mutation was more often seen in patients with lymph node metastasis. As BRAF (Montrer BRAF Anticorps) and NRAS mutations are rare in Taiwan, BRAF (Montrer BRAF Anticorps)- or NRAS-targeted therapies may be effective only for selected Taiwanese melanoma patients.

  10. Results shows the structural characterization of NRAS isoform 5 which overexpression results in more aggressive phenotype of melanoma. The protein was found highly flexible in aqueous solution, but forms a helix-turn-coil structure in the presence of trifluoroethanol.

Zebrafish GTPase NRas (NRAS) interaction partners

  1. Although oncogenic NRAS expression alone was found to be insufficient to promote tumor formation, loss of functional p53 (Montrer TP53 Anticorps) was found to collaborate with NRAS expression in the genesis of melanoma.

GTPase NRas (NRAS) profil antigène

Antigen Summary

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

Alternative names and synonyms associated with GTPase NRas (NRAS)

  • GTPase NRas (Tsp_01117) anticorps
  • African clawed frog N-ras (n-ras) anticorps
  • neuroblastoma ras oncogene (Nras) anticorps
  • neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS) anticorps
  • neuroblastoma RAS viral (v-ras) oncogene homolog (nras) anticorps
  • ALPS4 anticorps
  • AV095280 anticorps
  • fj99a10 anticorps
  • H-RAS anticorps
  • HRAS anticorps
  • N-RAS anticorps
  • NRAS anticorps
  • NRAS1 anticorps
  • NS6 anticorps
  • wu:fj99a10 anticorps
  • zgc:100761 anticorps
  • zras-b1 anticorps

Protein level used designations for anti-GTPase NRas (NRAS) Anticorps

GTPase NRas , transforming protein N-Ras , neuroblastoma RAS viral (v-ras) oncogene homolog , N-ras oncogene , p21 protein , N-ras protein part 4 , v-ras neuroblastoma RAS viral oncogene homolog , ras p21 , N-ras oncogene p21 , etID18709.8 , neuroblastoma RAS viral oncogene-like protein , neuroblastoma ras oncogene , v-Ha-ras Harvey rat sarcoma viral oncogene homolog

GENE ID SPECIES
10905151 Trichinella spiralis
399446 Xenopus laevis
24605 Rattus norvegicus
18176 Mus musculus
100135584 Cavia porcellus
4893 Homo sapiens
403872 Canis lupus familiaris
30380 Danio rerio
419885 Gallus gallus
100739349 Sus scrofa
506322 Bos taurus
100174317 Pongo abelii
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