Aperçu des produits pour anti-GTPase NRas (NRAS) Anticorps

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anti-GTPase NRas Anticorps (NRAS)
Chez www.anticorps-enligne.fr sont 102 GTPase NRas (NRAS) Anticorps de 17 de différents fournisseurs disponibles. De plus, nous expédions GTPase NRas Protéines (17) et GTPase NRas Kits (6) et beaucoup plus de produits pour cette protéine. Un total de 130 GTPase NRas produits sont actuellement listés.
ALPS4, AV095280, fj99a10, H-RAS, HRAS, N-RAS, NRAS, NRAS1, NS6, wu:fj99a10, zgc:100761, zras-b1

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anti-Rat (Rattus) GTPase NRas Anticorps:

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anti-GTPase NRas Anticorps mieux référencés

  1. Human Monoclonal GTPase NRas Primary Antibody pour EIA, WB - ABIN781533 : Rocks, Peyker, Bastiaens: Spatio-temporal segregation of Ras signals: one ship, three anchors, many harbors. dans Current opinion in cell biology 2006 (PubMed)
    Show all 3 references for 781533

  2. Human Polyclonal GTPase NRas Primary Antibody pour IHC, ELISA - ABIN302138 : Thomas, Edmiston, Alexander, Millikan, Groben, Hao, Tolbert, Berwick, Busam, Begg, Mattingly, Ollila, Tse, Hummer, Lee-Taylor, Conway: Number of nevi and early-life ambient UV exposure are associated with BRAF-mutant melanoma. dans Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007 (PubMed)

  3. Human Polyclonal GTPase NRas Primary Antibody pour FACS, IF - ABIN392152 : Smalley, Contractor, Nguyen, Xiao, Edwards, Muthusamy, King, Flaherty, Bosenberg, Herlyn, Nathanson: Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression. dans Cancer research 2008 (PubMed)

  4. Human Monoclonal GTPase NRas Primary Antibody pour WB - ABIN1882272 : Hall, Brown: Human N-ras: cDNA cloning and gene structure. dans Nucleic acids research 1985 (PubMed)

Plus d’anticorps contre GTPase NRas partenaires d’interaction

Mouse (Murine) GTPase NRas (NRAS) interaction partners

  1. loss of one allele of Hras (Montrer HRAS Anticorps) increased the sensitivity of mice to this carcinogen, and this effect was further exacerbated by the loss of the second Hras (Montrer HRAS Anticorps) allele. However, loss of one or both alleles of Nras failed to alter tumor burden, either in the absence or presence of Hras (Montrer HRAS Anticorps), after exposure to urethane.

  2. Genetic inactivation of Ezh2 (Montrer EZH2 Anticorps) or Eed (Montrer EED Anticorps) cooperates with NRASQ61K in leukemogenesis.

  3. Data indicate that S-phase kinase-associated protein 2 (SKP2) cooperates with N-Ras and AKT proto-oncogenes to promote hepatocarcinogenesis in vivo.

  4. Activated NRAS and aberrant Wnt (Montrer WNT2 Anticorps) signaling conspire to drive congenital melanocytic nevus syndrome.

  5. a crucial role of RXRa (Montrer RXRA Anticorps) in suppression of UVB-induced melanomas in the context of driver mutations such as activated CDK4 (Montrer CDK4 Anticorps)(R24C/R24C) or oncogenic NRAS(Q61K) and altered expression of p53 (Montrer TP53 Anticorps) and PTEN (Montrer PTEN Anticorps)

  6. This work explains the curious predominance in human melanoma of mutations of codon 61 of NRAS over other oncogenic NRAS mutations. we show that physiologic expression of NRASQ61R, but not NRASG12D, drives melanoma formation.

  7. These data reveal the L. major-enhanced CD40-induced N-Ras activation as a novel immune evasion strategy and the potential for Ras isoform-targeted antileishmanial immunotherapy and immunoprophylaxis.

  8. NRAS expression is required for the proliferative advantage of human AML (Montrer RUNX1 Anticorps) cell lines in vitro and for the maintenance of mouse Nras-mutant AML (Montrer RUNX1 Anticorps) in vivo

  9. There was a nearly complete correspondence between the signaling pathways that were regulated by N-ras in immune cell types.

  10. Cbfbeta (Montrer CBFB Anticorps)-SMMHC (Montrer MYH11 Anticorps) and Nras(G12D) promote the survival of preleukemic myeloid progenitors primed for leukemia by activation of the MEK (Montrer MDK Anticorps)/ERK (Montrer EPHB2 Anticorps)/Bim (Montrer BCL2L11 Anticorps) axis, and define Nras(LSL-G12D); Cbfb (Montrer CBFB Anticorps)(56M) mice as a valuable genetic model for the study of AML (Montrer RUNX1 Anticorps) therapies.

Human GTPase NRas (NRAS) interaction partners

  1. NRAS mutations were present in 1.2% of primary papillary thyroid carcinomas, 1.3% of lymph node metastasis, and 14.3% of distant metastasis.

  2. Data suggest that isoform-specific sequences in the allosteric lobes of HRAS (Montrer HRAS Anticorps), KRAS, and NRAS have an impact on biocatalysis (kinetics of GTP (Montrer AK3 Anticorps) hydrolysis) and interaction with c-Raf (Montrer RAF1 Anticorps) kinase, which must be due to allosteric effects on dynamics and conformational states, given the identical active sites of these isoenzymes.

  3. NRAS(Q61R) immunohistochemistry is a highly sensitive and specific tool that is useful for differentiating follicular-patterned thyroid tumors.

  4. NRAS variants were identified in 2 cases with a lethal presentation of Noonan syndrome.

  5. Mutation in NRAS gene is associated with chronic myelomonocytic leukemia.

  6. Compared with newly diagnosed multiple myeloma, an increased prevalence of mutations in the Ras pathway genes KRAS, NRAS, and/or BRAF (Montrer BRAF Anticorps) (72%), as well as TP53 (Montrer TP53 Anticorps) (26%), CRBN (Montrer CRBN Anticorps) (12%), and CRBN (Montrer CRBN Anticorps) pathway genes (10%) was observed.

  7. Our data suggest that testing for any RAS mutation is unlikely to change the clinical management of thyroid nodules that have indeterminate cytology

  8. Examination of clinical parameters of these tumors found those with APA (Montrer ENPEP Anticorps) of NRAS and c-JUN (Montrer JUN Anticorps) to be smaller and less proliferative

  9. Equilibrium dissociation constants were determined for the binding of HRAS, KRAS, NRAS and RRAS2 to the RAS binding (RB) domain of binding proteins.

  10. Studies indicate that RAS proteins were among the first oncogenes identified and are mutationally activated in 30% of all cancer types.

Zebrafish GTPase NRas (NRAS) interaction partners

  1. Although oncogenic NRAS expression alone was found to be insufficient to promote tumor formation, loss of functional p53 (Montrer TP53 Anticorps) was found to collaborate with NRAS expression in the genesis of melanoma.

GTPase NRas (NRAS) profil antigène

Antigen Summary

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

Alternative names and synonyms associated with GTPase NRas (NRAS)

  • GTPase NRas (Tsp_01117) anticorps
  • African clawed frog N-ras (n-ras) anticorps
  • neuroblastoma ras oncogene (Nras) anticorps
  • neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS) anticorps
  • neuroblastoma RAS viral (v-ras) oncogene homolog (nras) anticorps
  • ALPS4 anticorps
  • AV095280 anticorps
  • fj99a10 anticorps
  • H-RAS anticorps
  • HRAS anticorps
  • N-RAS anticorps
  • NRAS anticorps
  • NRAS1 anticorps
  • NS6 anticorps
  • wu:fj99a10 anticorps
  • zgc:100761 anticorps
  • zras-b1 anticorps

Protein level used designations for anti-GTPase NRas (NRAS) Anticorps

GTPase NRas , transforming protein N-Ras , neuroblastoma RAS viral (v-ras) oncogene homolog , N-ras oncogene , p21 protein , N-ras protein part 4 , v-ras neuroblastoma RAS viral oncogene homolog , ras p21 , N-ras oncogene p21 , etID18709.8 , neuroblastoma RAS viral oncogene-like protein , neuroblastoma ras oncogene , v-Ha-ras Harvey rat sarcoma viral oncogene homolog

10905151 Trichinella spiralis
399446 Xenopus laevis
24605 Rattus norvegicus
18176 Mus musculus
100135584 Cavia porcellus
4893 Homo sapiens
403872 Canis lupus familiaris
30380 Danio rerio
419885 Gallus gallus
100739349 Sus scrofa
506322 Bos taurus
100174317 Pongo abelii
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