Aperçu des produits pour PKC beta Protéines (PRKCB)

Full name:
Protein Kinase C, beta Protéines (PRKCB)
Chez www.anticorps-enligne.fr sont 22 Protein Kinase C, beta (PRKCB) Protéines de 8 de différents fournisseurs disponibles. De plus, nous expédions PKC beta Anticorps (192) et PKC beta Kits (33) et beaucoup plus de produits pour cette protéine. Un total de 261 PKC beta produits sont actuellement listés.
Synonymes:
A130082F03Rik, PKC, PKC-B, PKC-Beta, Pkcb, Prkcb, Prkcb1, Prkcb2, zgc:63591
afficher tous les protéines Gène GeneID UniProt
PRKCB 5579 P05771
PRKCB 18751 P68404
PRKCB 25023 P68403

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PKC beta Protéines (PRKCB) par origine

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Plus protéines pour PKC beta partenaires d'interaction

Human Protein Kinase C, beta (PRKCB) interaction partners

  1. a primary functional variant of PRKCB (rs35015313) was identified by genotype imputation using a phased panel of 1,070 Japanese individuals from a prospective, general population cohort study and subsequent in vitro functional analyses. These results may lead to improved understanding of the disease pathways involved in primary biliary cholangitis.

  2. our findings identify PRKCB gene as a novel candidate gene for familial Meniere's Disease (MD )and its expression gradient in supporting cells of the organ of Corti deserves attention, given the role of supporting cells in K(+ )recycling within the endolymph, and its apical turn location may explain the onset of hearing loss at low frequencies in MD

  3. Activation of the Pro-Oxidant PKCbetaII-p66Shc (Montrer SHC1 Protéines) Signaling Pathway Contributes to Pericyte Dysfunction in Skeletal Muscles of Patients With Diabetes With Critical Limb Ischemia

  4. Taken together, these data argue for a complex mechanism of PKC-beta-dependent regulation of SH (Montrer POLD3 Protéines)CA (p66) activation invol (Montrer SIGLEC1 Protéines)ving Ser(139) and a motif surroun (Montrer SIGLEC1 Protéines)ding Ser(213).

  5. The study aimed to identify a small set of genetic signatures that may reliably predict the individuals with a high genetic propensity to heroin addiction. A set of 4 genes (JUN (Montrer JUN Protéines), CEBPB (Montrer CEBPB Protéines), PRKCB, ENO2 (Montrer ENO2 Protéines), or CEBPG (Montrer CEBPG Protéines)) could predict the diagnosis of heroin addiction with the accuracy rate around 85% in our dataset.

  6. Our results provide compelling evidence that glucose-induced PKCalpha (Montrer PKCa Protéines)/PKCbeta-mediated inhibition of Kv current in vascular smooth muscle causes an enhanced constrictor response. Inhibition of Kv current causes a significant depolarization of vascular myocytes leading to marked vasoconstriction

  7. Data suggest that targeted manipulation of protein kinase C isoforms PKCalpha (Montrer PKCa Protéines), PKCbeta, and PKCeta might be beneficial in certain proteinuric kidney diseases with altered transient receptor potential cation channel subfamily C member 6 (Montrer TRPC6 Protéines) protein (TRPC6 (Montrer TRPC6 Protéines)) functions.

  8. Bone marrow stroma-induced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl-1 upregulation and is overcome by inhibiting the PI3Kdelta or PKCbeta signaling pathways.

  9. PPAR-delta (Montrer PPARD Protéines) and NKIRAS1 (Montrer NKIRAS1 Protéines) are downstream mediators in the PRKCB pathway in human umbilical vein endothelial cells.

  10. Lower hydrogen sulfide (Montrer SQRDL Protéines) is associated with cardiovascular mortality, which involves PKCBII/Akt (Montrer AKT1 Protéines) pathway in chronic hemodialysis patients.

Cow (Bovine) Protein Kinase C, beta (PRKCB) interaction partners

  1. The study identified the serine phosphorylation (p-Ser) sites induced by (Montrer IRS2 Protéines)PKC-Beta activation or AGT, which inhibits insulin-induced p-Tyr sites on IRS2 and its signals in endothelial cells.

Mouse (Murine) Protein Kinase C, beta (PRKCB) interaction partners

  1. Cytosolic NELL2 specifically interacts with PKC beta isotypes and inhibits PKC beta1 through direct binding to the N-terminal pseudosubstrate domain of PKC beta1.

  2. Taken together, these data argue for a complex mechanism of PKCbeta-dependent regulation of p66 (Montrer POLD3 Protéines) activation involving Ser (Montrer SIGLEC1 Protéines)(139) and a motif surrounding Ser (Montrer SIGLEC1 Protéines)(213).

  3. Translocation of PKC-betaII from the cytoplasm to membranes is required for phagocytosis of apoptotic cells and is inhibited by soluble beta-glucan

  4. repressor of myogenesis; opposes calcineurin (Montrer PPP3CA Protéines) function

  5. at the functionally mature calyx of Held synapse the Ca(2+)-dependent protein kinase C isoforms alpha and beta are necessary for post-tetanic potentiation, a form of plasticity thought to underlie short-term memory

  6. a new mechanism by which PKC-beta activation promotes EC dysfunction caused by the de-regulation of the IL-18 (Montrer IL18 Protéines)/IL-18BP (Montrer IL18BP Protéines) pathway, leading to increased VCAM-1 (Montrer VCAM1 Protéines) expression, monocyte/macrophage adhesion, and accelerated atherosclerotic plaque formation in diabetes

  7. These results demonstrate the importance of PKCbetaII in chronic lymphocytic leukemia-like disease progression and suggest a role for PKCalpha (Montrer PKCa Protéines) subversion in creating permissive conditions for leukemogenesis.

  8. PKCbeta2 inhibition protects mice from gut (Montrer GUSB Protéines) ischemia-reperfusion injury by suppressing the adaptor p66(Shc)-mediated oxidative stress and subsequent apoptosis.

  9. PKC-alpha (Montrer PKCa Protéines) and -betaIotaIota are the predominant isoforms in the developing optic pathway, whereas PKC-epsilon (Montrer PRKCE Protéines) is the major form in the chiasmatic neurons.

  10. STAT3 (Montrer STAT3 Protéines) bound to previously undescribed negative regulatory elements within the promoter of PRKCB, which encodes PKCbetaII.

Profil protéine PKC beta (PRKCB)

Profil protéine

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with PKC beta (PRKCB)

  • protein kinase C, beta b (prkcbb)
  • protein kinase C, beta (PRKCB)
  • protein kinase C, beta (Prkcb)
  • A130082F03Rik Protéine
  • PKC Protéine
  • PKC-B Protéine
  • PKC-Beta Protéine
  • Pkcb Protéine
  • Prkcb Protéine
  • Prkcb1 Protéine
  • Prkcb2 Protéine
  • zgc:63591 Protéine

Protein level used designations for PRKCB

PKC-beta , protein kinase C beta type , protein kinase C, beta 1 , protein kinase C, beta , PKC-B , protein kinase C, beta 1 polypeptide , protein kinase C beta 2 , protein kinase C beta-II , protein kinase C beta I , protein kinase C beta II , protein kinase C beta 1

GENE ID SPECIES
393953 Danio rerio
100590939 Nomascus leucogenys
5579 Homo sapiens
397183 Sus scrofa
282325 Bos taurus
18751 Mus musculus
25023 Rattus norvegicus
100037719 Oryctolagus cuniculus
489968 Canis lupus familiaris
416567 Gallus gallus
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