PKC beta Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2729604

Détail du produit

Antigène: PKC beta (PRKCB) (Protein Kinase C, beta (PRKCB))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PKC beta protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human PRKCB (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: PKC beta (PRKCB) (Protein Kinase C, beta (PRKCB))

Autre désignation: Prkcb (PRKCB Produits)

Synonymes: PKC-beta Protein, PKCB Protein, PRKCB1 Protein, PRKCB2 Protein, A130082F03Rik Protein, PKC-Beta Protein, Pkcb Protein, Prkcb1 Protein, Prkcb2 Protein, PKC-B Protein, Prkcb Protein, prkcb1 Protein, zgc:63591 Protein, PKC Protein, PRKCB_tv2 Protein, Pkc53E Protein, prkcb1l Protein, zgc:64063 Protein, protein kinase C beta Protein, protein kinase C, beta Protein, protein kinase C, beta b Protein, protein kinase C, beta a Protein, PRKCB Protein, Prkcb Protein, prkcbb Protein, prkcba Protein

Sujet: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Poids moléculaire: 76.7 kDa

NCBI Accession: NP_997700

Pathways: Signalisation WNT, TCR Signaling, Thyroid Hormone Synthesis, Nuclear Hormone Receptor Binding, Chromatin Binding, Myometrial Relaxation and Contraction, VEGF Signaling, Unfolded Protein Response, BCR Signaling