anti-ADP-Ribosylation Factor-Like 13B (ARL13B) Anticorps

ARL13B encodes a member of the ADP-ribosylation factor-like family. De plus, nous expédions ARL13B Protéines (6) et ARL13B Kits (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ARL13B 304037  
ARL13B 200894 Q3SXY8
ARL13B 68146 Q640N2
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Top anti-ARL13B Anticorps sur anticorps-enligne.fr

Showing 10 out of 28 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-ARL13B Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>721_B cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-ARL13B Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Jurkat cell lysate WB Suggested Anti-ARL13B <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Jurkat cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Cobaye Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué IHC (p), WB Western Blot: ARL13B Antibody [NBP2-15463] - Sample (30 ug of whole cell lysate) A: 293T 10% SDS PAGE gel, diluted at 1:1000. Immunohistochemistry-Paraffin: ARL13B Antibody [NBP2-15463] - Immunohistochemical analysis of paraffin-embedded U87 xenograft, using antibody at 1:500 dilution. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$514.63
Détails
Humain Lapin Inconjugué IF, WB Western blot analysis of extracts of LO2 and U87 cells, using ARL13B antibody. 100 μL Connectez-vous pour afficher 16 Days
$476.15
Détails
Humain Lapin Inconjugué IHC, IHC (p) Immunohistochemistry-Paraffin: ARL13B Antibody [NBP2-14312] Staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts. Immunohistochemistry-Paraffin: ARL13B Antibody  - Staining of human skeletal muscle shows low expression as expected. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Lapin Inconjugué ELISA, WB 50 μg Connectez-vous pour afficher 2 to 3 Days
$446.88
Détails
Humain Lapin Inconjugué WB Western blot analysis of extracts of SKOV3 cells, using ARL13B antibody (ABIN5973000) at 1/1000 dilution. 100 μL Connectez-vous pour afficher 11 to 16 Days
$412.19
Détails
Chien Lapin Inconjugué IHC, WB Western blot analysis of extracts of mouse brain tissue, using ARL13B antibody. ABIN6272844 at 1/100 staining Human liver cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails

ARL13B Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité
Rat (Rattus)


Human ,
,
,
Mouse (Murine)


anti-ARL13B Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal ARL13B Primary Antibody pour WB - ABIN2785090 : Fan, Esmail, Ansley, Blacque, Boroevich, Ross, Moore, Badano, May-Simera, Compton, Green, Lewis, van Haelst, Parfrey, Baillie, Beales, Katsanis, Davidson, Leroux: Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome. dans Nature genetics 2004 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre ARL13B partenaires d’interaction

Zebrafish ADP-Ribosylation Factor-Like 13B (ARL13B) interaction partners

  1. loss of Arl13b leads to slow photoreceptor degeneration, but can be exacerbated by the loss of vangl2 (Montrer VANGL2 Anticorps). Importantly, the data show that Arl13b can genetically and physically interact with Vangl2 (Montrer VANGL2 Anticorps) and this association is important for normal photoreceptor structure.

  2. Arl13b is an important effector of ciliary membrane biogenesis and ciliary length regulation.

  3. Cilia localization is essential for in vivo functions of the Joubert syndrome protein arl13b.

Human ADP-Ribosylation Factor-Like 13B (ARL13B) interaction partners

  1. A novel homozygous loss of function mutation in ARL13B was identified in patients with Joubert syndrome

  2. High Arl13b expression is associated with medulloblastoma formation.

  3. the results show that palmitoylation plays a unique and critical role in controlling the localization, stability, abundance, and thus function of ARL13b. Pharmacological manipulation of protein palmitoylation may be a strategy to alter cilia function.

  4. Our results show how Arl13b participates in Hedgehog (Montrer SHH Anticorps) pathway activation in gastric cancer

  5. Reduced primary cilia length and altered Arl13b expression are associated with deregulated chondrocyte Hedgehog (Montrer SHH Anticorps) signaling in alkaptonuria (Montrer HGD Anticorps).

  6. ARL13B regulates IFT-A-mediated retrograde protein trafficking within cilia through its interaction with INPP5E.

  7. Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase (Montrer RACGAP1 Anticorps) and ARL3 guanine nucleotide exchange factor (Montrer RASGRF1 Anticorps) (GEF (Montrer SLC2A4RG Anticorps)).(

  8. Thus our data identify a novel ARL13B variant that causes JS and retinopathy and suggest an extension of the phenotypic spectrum of ARL13B mutations to obesity.

  9. We conclude that MKS/NPHP modules comprise a TZ barrier to ARL-13 diffusion, whereas IFT genes predominantly facilitate ARL-13 ciliary entry and/or retention via active transport mechanisms.

  10. X-ray crystallography of Arl13B demonstrates involvement of mutations R79Q and R200C in stabilizing intramolecular interactions.

Mouse (Murine) ADP-Ribosylation Factor-Like 13B (ARL13B) interaction partners

  1. High Arl13b expression is associated with medulloblastoma formation.

  2. Arl13b dysfunction resulted in hennin cell stagnation due to poor growth factor signaling and impaired detection of extracellular electrical gradients.

  3. Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase (Montrer RACGAP1 Anticorps) and ARL3 guanine nucleotide exchange factor (Montrer ARHGEF12 Anticorps) (GEF (Montrer ARHGEF2 Anticorps)).(

  4. To investigate whether Arl13b has a role in ciliogenesis in mammalian kidney and whether loss of function of Arl13b leads to cystic kidneys in mammals, we generated a mouse model with kidney-specific conditional knockout of Arl13b Deletion of Arl13b in the distal nephron at the perinatal stage led to a cilia biogenesis defect and rapid kidney cyst formation

  5. The authors show that the ciliary G-protein Arl13B, mutated in Joubert syndrome, is the guanine nucleotide exchange factor for Arl3, and its function is conserved in evolution

  6. A new role for Arl13b in actin cytoskeleton remodeling through the interaction with Myh9 (Montrer MYH9 Anticorps).

  7. Early neuroepithelial deletion of ciliary Arl13b reversed the apical-basal polarity of radial progenitors & caused aberrant neuronal placement. Arl13b signaling in primary cilia is crucial for initial formation of a polarized radial glial scaffold.

  8. guidance cue receptors essential for interneuronal migration localize to interneuronal primary cilia, but their concentration and dynamics are altered in the absence of Arl13b

  9. By deleting Arl13b in mouse, we induced low-level constitutive GliA function at specific developmental stages and defined a crucial period prior to E10.5 when shifts in the level of GliA cause cells to change their fate

  10. Study shows the cilia protein Arl13b is required for left right axis specification as its absence results in heterotaxia; the defect originates in the node where Cerl2 (Montrer DAND5 Anticorps) is not downregulated and asymmetric expression of Nodal is not maintained resulting in symmetric expression of both genes.

ARL13B profil antigène

Profil protéine

This gene encodes a member of the ADP-ribosylation factor-like family. The encoded protein is a small GTPase that contains both N-terminal and C-terminal guanine nucleotide-binding motifs. This protein is localized in the cilia and plays a role in cilia formation and in maintenance of cilia. Mutations in this gene are the cause of Joubert syndrome 8. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with ARL13B

  • ADP-ribosylation factor like GTPase 13B (Arl13b) anticorps
  • ADP ribosylation factor like GTPase 13B (ARL13B) anticorps
  • ADP ribosylation factor like GTPase 13B (arl13b) anticorps
  • ADP-ribosylation factor-like 13b (arl13b) anticorps
  • ADP-ribosylation factor-like 13B (Arl13b) anticorps
  • A530097K21Rik anticorps
  • A930014M17Rik anticorps
  • Arl2l1 anticorps
  • C530009C10Rik anticorps
  • chunp6872 anticorps
  • fc23g07 anticorps
  • hnn anticorps
  • JBTS8 anticorps
  • MGC185757 anticorps
  • wu:fc23g07 anticorps
  • zgc:123149 anticorps

Protein level used designations for ARL13B

ADP-ribosylation factor-like protein 13B , ADP-ribosylation factor-like 2-like 1 , ADP-ribosylation factor-like 13B , ADP-ribosylation factor-like protein 13B-like , ADP-ribosylation factor-like protein 2-like 1 , ARL2-like protein 1 , protein scorpion , scorpion , un-named hi459 , unm hi459

GENE ID SPECIES
304037 Rattus norvegicus
418431 Gallus gallus
460534 Pan troglodytes
487934 Canis lupus familiaris
512781 Bos taurus
694959 Macaca mulatta
100124913 Xenopus (Silurana) tropicalis
100413286 Callithrix jacchus
100456801 Pongo abelii
100467626 Ailuropoda melanoleuca
100600917 Nomascus leucogenys
286784 Danio rerio
200894 Homo sapiens
68146 Mus musculus
Fournisseurs de qualité sélectionnés pour anti-ARL13B (ARL13B) Anticorps
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