Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) Kits ELISA

This protein belongs to the aldehyde dehydrogenase family of proteins. De plus, nous expédions Aldehyde Dehydrogenase 2 Family (Mitochondrial) Anticorps (177) et Aldehyde Dehydrogenase 2 Family (Mitochondrial) Protéines (19) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
ALDH2 217 P05091
ALDH2 29539 P11884
ALDH2 11669 P47738
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Top Aldehyde Dehydrogenase 2 Family (Mitochondrial) Kits ELISA sur anticorps-enligne.fr

Showing 10 out of 37 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 0.124 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Connectez-vous pour afficher 13 to 16 Days
$736.84
Détails
Rat 0.33 ng/mL 0.78 ng/mL - 50 ng/mL 96 Tests Connectez-vous pour afficher 13 to 16 Days
$800.00
Détails
Souris 5.8 pg/mL 23.5-1500 pg/mL Typical standard curve 96 Tests Connectez-vous pour afficher 15 to 18 Days
$910.56
Détails
Poulet 0.188 ng/mL 0.313-20 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Singe 0.188 ng/mL 0.313-20 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Porc 0.188 ng/mL 0.313-20 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Lapin 75 pg/mL 125-8000 pg/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Mouton 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$824.38
Détails
Humain 46.875 pg/mL 78.125 pg/mL - 5000 pg/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Boeuf (Vache)
  96 Tests Connectez-vous pour afficher 15 to 18 Days
$1,029.60
Détails

Aldehyde Dehydrogenase 2 Family (Mitochondrial) Kits ELISA mieux référencés

  1. Human ALDH2 Kit ELISA pour Sandwich ELISA - ABIN415136 : Chen, Zhou, Xiao, Huang, Zhang, Gu, Tang: Inhibition of ALDH2 protects PC12 cells against formaldehyde-induced cytotoxicity: involving the protection of hydrogen sulphide. dans Clinical and experimental pharmacology & physiology 2017 (PubMed)

Plus Kits ELISA pour Aldehyde Dehydrogenase 2 Family (Mitochondrial) partenaires d'interaction

Rabbit Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. ALDH-2 is involved in the remote ischemic preconditioning pathway.

Human Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. Our results highlight that ALDH2 impairment accelerates the acquisition of a premature senescent phenotype, a change likely to be associated with the observed reduction of mitochondrial respiration and reserve capacity.

  2. we identified three novel SNPs associated with ferritin in ALDH2. Men carrying the mutated genotype of rs671 have lower serum ferritin levels.

  3. common variants of ADH1B and ALDH2 are independently associated with gout. Our findings likewise suggest that genotyping these variants can be useful for the evaluation of gout risk.

  4. ALDH2 polymorphism is associated with Gastric and esophageal cancer.

  5. The use of aldehyde dehydrogenase (ALDH) for isolating and identifying sub-populations of mesenchymal stromal cells (MSCs) with specific gene profile may represent an alternative method to provide solutions for targeted therapeutic applications.

  6. The analysis of the effect of the individual SNPs(PON1, IL-6, ITGB3, and ALDH2 ) and GRS groups on different lipid profile parameters revealed no significant association of any of the tested SNPs with any lipid parameter, however, the GRS groups showed marginally significant for TC and highly significant association for TG, LDL-c and HDL-c

  7. In a Chinese Han population with dyslipidemia, individuals with A/A or A/G genotypes of rs671 in the Aldehyde Dehydrogenase, Mitochondrial gene have a higher coronary artery disease risk, if they lack physical activity and take fried food regularly, than individuals with G/G genotypes.

  8. aldehyde dehydrogenase 2 (ALDH2) is found to be transcriptionally regulated by VHL and contributes to enhanced anthracyclines cytotoxicity in clear cell renal cell carcinoma cells.

  9. ardiac-specific expression of the human ALDH2 gene in mice augmented myocardial ALDH2 activity but did not improve cardiac function in response to pressure overload. After 12 weeks of transverse aortic constriction , ALDH2 transgenic mice had larger hearts than their wild-type littermates and lower capillary density

  10. Study revealed that the rs10744777 polymorphism in ALDH2 was an independent risk factor for ischemic stroke in Chinese male, but not in Chinese female.

  11. ALDH2 gene polymorphism is associated with liver diseases.

  12. In the 7,966 individuals from the Hakka population of China in this study, the frequencies of the ALDH2 genotypes *1/*1, *1/*2 and *2/*2 were 52.03%, 39.67%, and 8.30%, respectively; 47.97% of the individuals were found to carry the ALDH2*2 genotype, which was associated with a deficiency in the aldehyde dehydrogenase (ALDH2) enzyme activity.

  13. Here the authors demonstrate that a missense single nucleotide polymorphism in the ALDH2 gene, rs671 (ALDH2*2), is significantly associated with hip fracture (odds ratio = 2.48, 95% confidence interval: 1.20-5.10, p = 0.021). The rs671 single nucleotide polymorphism was also significantly associated with osteoporosis development (odds ratio = 2.04, 95% confidence interval: 1.07-3.88, p = 0.040).

  14. the mediation effects of single nucleotide polymorphisms (SNPs) in the ADH1B and ALDH2 genes on hepatocellular carcinoma, were investigated.

  15. Three novel SNPs of ALDH2 gene were suggestively significantly associated with serum folate levels.

  16. Coronary Artery Disease patients with mutated ALDH2 genotype are inclined to suffer with coronary artery lesions than wild type subjects.

  17. he ALDH2 Glu504Lys polymorphism may be associated with susceptibility to colorectal cancer (meta-analysis).

  18. rs17033 of ADH1B and rs671 of ALDH2 SNPs were associated with GC risk and smoking habit may further modify the effect of rs671. Conversely, rs4147536 of ADH1B might have a protective role in our study population.

  19. Many studies have shown that ALDH2 polymorphism is a genetic instrument for alcohol use in Mendelian randomization analysis. [review]

  20. Divers studies provide evidence that ALDH2*2 mutant allele (deficiency genotype) is present in nearly half of the East Asian population with ischemic reperfusion injury. [review]

Cow (Bovine) Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. ALDH2-catalyzed NO formation is necessary and sufficient for nitroglycerin bioactivation in vascular smooth muscle cells.

  2. ACADM and ALDH2 were predicted to be the target genes of miR-224

  3. analysis of bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases ALDH1 and ALDH2

Mouse (Murine) Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. data revealed that ALDH2 enzyme may suppress myocardial autophagy possibly through a complex JNK-Bcl-2 and IKKbeta-AMPK-dependent mechanism en route to accentuation of myocardial remodeling and contractile dysfunction in aging.

  2. results thus suggest that ALDH2 is indispensable for the favorable cardiac effect of low-to-moderate alcohol consumption and ALDH2 deficiency may lead to unexpected cardiac dysfunctions via enhancing myocardial apoptosis and necroptosis.

  3. ALDH2 activation improved ethanol-induced cardiac damage and decreased angiotensin and angiotensin II in hearts.

  4. ALDH2 overexpression inhibited the expression of c-Jun N-terminal kinase (JNK)-1, activated protein 1 (AP-1), insulin receptor substrate 1 (IRS-1), 4- hydroxynonenal, caspase 3, transforming growth factor beta1, and collagen I and III, and enhanced Akt phosphorylation.

  5. Study found ALDH2*2 diabetic mice exhibit diastolic dysfunction and preserved systolic function at rest, similar to clinical heart failure of preserved ejection fraction.

  6. ALDH2 deficiency reduced the therapeutic effect of ALDHbr cells in the mice model of ischemic hind limb due to decreased anaerobic glycolysis and increased mitochondrial ROS generation.

  7. osteoblast differentiation is impaired in the absence of Aldh2 gene.

  8. ALDH2 plays a protective role in cyclophosphamide-induced acute hepatotoxicity via attenuating oxidative stress and detoxifying reactive aldehydes.

  9. Deficiency in ALDH2 activity may contribute to increased cisplatin sensitivity and cytotoxicity by producing more ROS by the treatment.

  10. our data suggest that ALDH2 serves as an indispensable cardioprotective factor against insulin resistance-induced cardiomyopathy with a mechanism possibly associated with facilitation of the Sirt3-dependent PGC-1alpha deacetylation.

  11. Findings suggested that ALDH2 can influence atherosclerotic plaque development and vulnerability, and inflammation via MAPK, NF-kappaB and AP-1 signaling pathways.

  12. ALDH2 deficiency triggers decompensation of metabolic reserves and energy metabolism disturbances in early diabetic hearts.

  13. Results show that ALDH2 is required for a normal adipogenesis and its expression in white adipose tissue is negatively correlated with obesity. Also, the study provides evidence that PKCepsilon-ALDH2 pathway positively regulates adipocyte differentiation by regulation of PPARgamma transcriptional activity.

  14. In knock-in mice in which ALDH2 enzymatic activity is maximally reduced, cardio-protection in ischemic-reperfused hearts is lacking.

  15. Mitochondrial aldehyde dehydrogenase 2 (ALDH2) overexpression attenuates exhaustive exercise-induced mitochondrial oxidative stress

  16. ALDH2-catalyzed NO formation is necessary and sufficient for nitroglycerin bioactivation in vascular smooth muscle cells.

  17. capable of modulating the aggressive, highly metastatic phenotype of hepatocellular carcinomas in vivo

  18. prolonged treatment of apoE(-/-) mice with Alda-1 led to the beneficial changes in the expression of genes and proteins related to neuroplasticity and mitochondrial function.

  19. ALDH2 activation is adequate to improve the autophagy flux by reducing the carbonyl modification on SIRT1, which in turn plays an important role in maintaining cardiac health during aging.

  20. Our findings provide new insight into the preventive role of oesophageal ALDH2 against acetaldehyde-derived DNA damage.

Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) profil antigène

Antigen Summary

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with ALDH2

  • aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1 (aldh2.1) anticorps
  • aldehyde dehydrogenase 2 family (mitochondrial) L homeolog (aldh2.L) anticorps
  • aldehyde dehydrogenase 2 family (mitochondrial) (aldh2) anticorps
  • aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2) anticorps
  • aldehyde dehydrogenase 2 (aldh2) anticorps
  • aldehyde dehydrogenase (RHA1_RS43090) anticorps
  • aldehyde dehydrogenase (NAD(+)) (aldH2) anticorps
  • hypothetical protein (OE_RS03015) anticorps
  • aldehyde dehydrogenase (aldH2) anticorps
  • aldehyde dehydrogenase 2 family (mitochondrial) (Aldh2) anticorps
  • aldehyde dehydrogenase 2, mitochondrial (Aldh2) anticorps
  • Ahd-5 anticorps
  • Ahd5 anticorps
  • ALDH-E2 anticorps
  • aldh2 anticorps
  • aldh2a anticorps
  • ALDHI anticorps
  • ALDM anticorps
  • MGC80785 anticorps
  • rf2b anticorps
  • zgc:63786 anticorps

Protein level used designations for ALDH2

aldehyde dehydrogenase 2 , aldehyde dehydrogenase 2 family (mitochondrial) , aldehyde dehydrogenase 2 family (mitochondrial)a , aldehyde dehydrogenase 2.1 , mitochondrial aldehyde dehydrogenase 2 , ALDH2B6 , mitochondrial aldehyde dehydrogenase RF2B , aldehyde dehydrogenase , aldehyde dehydrogenase (NAD(+)) , ALDH class 2 , ALDH-E2 , aldehyde dehydrogenase, mitochondrial , aldehyde dehydrogenase, mitochondrial-like , acetaldehyde dehydrogenase 2 , liver mitochondrial ALDH , nucleus-encoded mitochondrial aldehyde dehydrogenase 2 , ALDH1 , aldehyde dehydrogenase 2, mitochondrial , mitochondrial aldehyde dehydrogenase , ALDHI , AHD-M1

GENE ID SPECIES
393462 Danio rerio
446857 Xenopus laevis
448267 Xenopus (Silurana) tropicalis
452252 Pan troglodytes
542567 Zea mays
713451 Macaca mulatta
4226489 Rhodococcus jostii RHA1
5776113 Staphylococcus aureus subsp. aureus USA300_TCH1516
5952690 Halobacterium salinarum R1
9005267 Rhodobacter capsulatus SB 1003
100171596 Pongo abelii
100217978 Taeniopygia guttata
100338523 Oryctolagus cuniculus
100388478 Callithrix jacchus
217 Homo sapiens
29539 Rattus norvegicus
610941 Canis lupus familiaris
733685 Sus scrofa
508629 Bos taurus
416880 Gallus gallus
11669 Mus musculus
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