Ankyrin Repeat Domain 27 (VPS9 Domain) Protéines (ANKRD27)

May be a Rab21 guanine exchange factor and regulate endosome dynamics.. De plus, nous expédions ANKRD27 Anticorps (23) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
ANKRD27 84079 Q96NW4
ANKRD27 245886 Q3UMR0
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Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,741.67
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,741.67
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
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ANKRD27 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Mouse (Murine)

Plus protéines pour Ankyrin Repeat Domain 27 (VPS9 Domain) (ANKRD27) partenaires d'interaction

Human Ankyrin Repeat Domain 27 (VPS9 Domain) (ANKRD27) interaction partners

  1. VARP regulates endosomal trafficking and and retromer-mediated endosome-to-plasma membrane sorting of transmembrane proteins by binding to rab GTP-Binding Proteins and R-SNARE VAMP7 [review].

  2. Eosinophilic esophagitis was associate with increased expression of ANKRD27.

  3. VAMP7-SNARE motif is trapped between Varp and the VAMP7 longin domain, and hence Varp kinetically inhibits the ability of VAMP7 to form SNARE complexes

  4. Varp physically interacts with Rab38, and preferentially binds to the active GTP-bound form of Rab38 both in vitro and in vivo.

  5. show that TI-VAMP interacts with the Vps9 domain and ankyrin-repeat-containing protein Varp, a guanine nucleotide exchange factor of the small GTPase Rab21, through a specific domain herein called the interacting domain.

Mouse (Murine) Ankyrin Repeat Domain 27 (VPS9 Domain) (ANKRD27) interaction partners

  1. RACK1 competes with Rab40C for binding to the ANKR2 domain of Varp and regulates dendrite outgrowth through stabilization of Varp in mouse melanocytes

  2. both the Rab32/38 binding activity and VAMP7 binding activity of Varp are essential for trafficking of Tyrp1 in melanocytes but activation of Rab21 by the VPS9 domain is not necessary for Tyrp1 trafficking

  3. Varp is a potential Rab21 guanine nucleotide exchange factor and might regulate endosome dynamics in vivo

  4. Varp functions as the Rab32/38 effector that controls trafficking of Tyrp1 in melanocytes.

Profil protéine ANKRD27

Profil protéine

May be a Rab21 guanine exchange factor and regulate endosome dynamics.

Gene names and symbols associated with ANKRD27

  • ankyrin repeat domain 27 (ANKRD27)
  • ankyrin repeat domain 27 (VPS9 domain) (Ankrd27)
  • AA408090 Protéine
  • BC016493 Protéine
  • D330003H11Rik Protéine
  • Varp Protéine

Protein level used designations for ANKRD27

VPS9 domain-containing protein , VPS9-ankyrin-repeat protein , Vps9 domain and ankyrin-repeat-containing protein , ankyrin repeat domain-containing protein 27 , VPS9-ankyrin repeat-containing protein , mFLJ00040 protein

GENE ID SPECIES
84079 Homo sapiens
245886 Mus musculus
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