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Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. De plus, nous expédions APOA4 Anticorps (184) et APOA4 Kits (65) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 28 products:
The genotype-risk associations were examined between APOA4 (rs5095, rs675, rs5110) and obesity-related phenotypes and other comorbidities in Sucre, Venezuela. There was a higher average waist-hip ratio among rs5095 homozygotes and for conicity index among homozygotes for rs5110.
Apolipoprotein L1 (Montrer APOL1 Protéines) and apolipoprotein A-IV and their association with kidney function
APOA-IV glycation is associated with coronary artery disease severity in patients with Type 2 Diabetes Mellitus.
These findings indicate that LZIP (Montrer CREB3 Protéines) is a novel modulator of APOA4 expression and hepatic lipid metabolism.
Study discovered novel and independent associations of prediabetes and related traits with MASP1 (Montrer MASP1 Protéines), and some evidence for associations with THBS1 (Montrer THBS1 Protéines), GPLD1 (Montrer GPLD1 Protéines) and ApoA-IV, suggesting a role for these proteins in the pathophysiology of type 2 diabetes.
Analyses of SNP-scores indicate potential causal effects of kidney function and by lesser extent triglycerides on apoA-IV concentrations.
Low levels of APOA1 (Montrer APOA1 Protéines), APOC3 (Montrer APOC3 Protéines), and APOA4 are associated with risk of Alzheimer disease.
Single nucleotide polymorphisms (Rs7396835) of APOA4 protein did not increase the risk of CHD (Montrer CHDH Protéines) in the Chinese population.
ApoA-IV colocalizes with NR4A1 (Montrer NR4A1 Protéines), which suppresses G6Pase (Montrer G6PC Protéines) and PEPCK (Montrer PEPCK Protéines) gene expression at the transcriptional level, reducing hepatic glucose output and lowering blood glucose.
the present findings reveal that High-altitude polycythemia -induced gastric mucosal lesion inspires the protection responses by up-regulating APOA4 and APOC3 (Montrer APOC3 Protéines), and down-regulating GIF (Montrer GIF Protéines).
zebrafish ApoA-IV performs a conserved role to that in rat in the regulation of food intake by transiently overexpressing ApoA (Montrer APOA1 Protéines)-IVb.
MTTP (Montrer MTTP Protéines) is regulated by apo A-IV in manner to promote increased packaging of triglyceride into chylomicron core, which may be important in neonatal fat absorption.
down-regulation of apolipoprotein A-I (Montrer APOA1 Protéines) and A-IV messages in the liver may be mediated by interleukin 6 (Montrer IL6 Protéines) and tumor necrosis factor-alpha (Montrer TNF Protéines)
Hepatocyte nuclear factor 4 alpha (HNF-4 alpha (Montrer HNF4A Protéines))induces apoliprotein IV gene in response to dietary lipids in the intestine.
APOA4 genes with SNPs
Upregulation of the intestinal apolipoprotein APOA-IV in horses with chronic laminitis was confirmed by western blot.[APOA-IV]
This study uncovers an anti-sense lncRNA (APOA4-AS), which is co-expressed with APOA4, and concordantly and specifically regulates APOA4 expression both in vitro and in vivo with the involvement of HuR (Montrer ELAVL1 Protéines).
Our findings may throw light on the function of ApoA4 in inflammatory responses and acute-phase reactions, as well as the development of SERPINA3 (Montrer SERPINA3 Protéines) relative diseases.
Very Low Density Lipoprotein (VLDL) assembly and CREBH (Montrer CREB3L3 Protéines) activation play key roles in the response to hepatic steatosis by up-regulating apoA-IV and promoting assembly and secretion of larger, more triglyceride - enriched VLDL particles.
It was suggested that increased ileal GPR119 (Montrer GPR119 Protéines) is a potential mechanism by which GLP-1 (Montrer GCG Protéines) secretion is enhanced in apoA-IV-/- mice.
these data suggest that apoA-IV is not necessary for the metabolic improvements shown with VSG, but also suggest an interesting role for apoA-IV in regulating macronutrient preference and hepatic triglyceride levels.
These results reveal ApoA-IV as a novel follicle-associated epithelium-specific marker especially in the upper small intestine of adult mice.
transcriptional regulation of apolipoprotein A-IV by the transcription factor CREBH (Montrer CREB3L3 Protéines)
apoA-IV inhibits hepatic gluconeogenesis by decreasing Glc-6-Pase (Montrer G6PC Protéines) and PEPCK (Montrer PEPCK Protéines) gene expression through NR1D1 (Montrer NR1D1 Protéines).
Hepatic steatosis in mice induces hepatic apoA-IV expression, which in turn promotes lipoprotein particle expansion and reduces hepatic lipid burden without increasing the number of secreted atherogenic apoB (Montrer APOB Protéines)-containing lipoprotein particles.
Data indicate that plasma lipids, lipid absorption, and microsomal triglyceride transfer protein (MTP (Montrer MTTP Protéines)), FoxO1 (Montrer FOXO1 Protéines), and FoxA2 (Montrer FOXA2 Protéines) levels are lower at night and at mealtime in apoAIV-/- mice.
Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396-residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A-IV is a potent activator of lecithin-cholesterol acyltransferase in vitro.
, apolipoprotein A4
, Apo A-IV
, apolipoprotein A-IV
, apolipoprotein A-IV-like