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may play a role in neural cell growth [RGD, Feb 2006].. De plus, nous expédions BZW2 Protéines (8) et beaucoup plus de produits pour cette protéine.
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5MP1 is a novel oncogene that reprograms c-Myc translation in CRC. 5MP1 could be a potential therapeutic target to overcome therapeutic resistance conferred by tumor heterogeneity of CRC.
These data demonstrated that the knockdown of BZW2 suppresses protein phosphorylation in the Akt/mTOR signaling pathway. These observations suggest that BZW2 is upregulated and has a pro-tumor effect in osteosarcoma via activation of the Akt/mTOR signaling pathway and thus is a potential target for gene therapy.
results reveal a surprising role for BZW1 and BZW2 in maintaining homeostatic stringency of start codon selection, and taking into account recent biochemical, genetic and structural insights into eukaryotic initiation, suggest a model for BZW1 and BZW2 function
Data show that eIF5-mimic protein (5MP) represses non-AUG translation by competing with translation initiation factor 5 (eIF5) for the Met-tRNAi-binding factor eIF2.
overexpression of eIF5 and 5MP induces translation of ATF4
5MP1 (BZW2) acts as a partial mimic and competitor of eIF5, interfering with the key steps by which eIF5 regulates eIF2 function.
Transcripts highly enriched in ovary; gene identified as candidate female fertility factor.
may play a role in neural cell growth
basic leucine zipper and W2 domain-containing protein 2
, basic leucine zipper and W2 domains 2
, basic leucine zipper and W2 domain-containing protein 2-like
, brain development-related molecule 2