anti-Beaded Filament Structural Protein 2, Phakinin (BFSP2) Anticorps

More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. De plus, nous expédions BFSP2 Protéines (4) et BFSP2 Kits (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
BFSP2 8419 Q13515
BFSP2 107993 Q6NVD9
BFSP2 501046  
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Top anti-BFSP2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 48 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-BFSP2 Antibody Titration: 1.0 ug/ml Positive Control: 293T Whole Cell 100 μL 2 to 3 Days
$289.00
Détails
Souris Lapin Inconjugué WB Western blot analysis of extracts of mouse eye, using BFSP2 antibody (ABIN6290111) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s. 50 μL 11 to 13 Days
$305.01
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Antigen: 0.2ug/100ul, Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000, Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000, TMB staining, Read the data in MicroplateReader by 450nm Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. 100 μL 3 to 7 Days
$327.80
Détails
Humain Souris Inconjugué WB   100 μL 11 to 14 Days
$522.50
Détails
Humain Souris Inconjugué IHC, IHC (p), WB   100 μL 11 to 14 Days
$522.50
Détails
Boeuf (Vache) Lapin Inconjugué WB   100 μL 11 to 14 Days
$551.83
Détails
Humain Lapin Alexa Fluor 594 IF (p)   100 μL 14 to 21 Days
$430.10
Détails
Humain Lapin Cy3 IF (p)   100 μL 14 to 21 Days
$430.10
Détails
Humain Lapin Cy5 IF (p)   100 μL 14 to 21 Days
$430.10
Détails
Humain Lapin Cy5.5 IF (p)   100 μL 14 to 21 Days
$430.10
Détails

Plus d’anticorps contre BFSP2 partenaires d’interaction

Human Beaded Filament Structural Protein 2, Phakinin (BFSP2) interaction partners

  1. The results suggest that the N-terminal domain of CRYAA is required during in vitro complex formation with filensin and phakinin.

  2. We report a novel mutation (p.G112E) in the BFSP2 gene, underscoring the physiological importance of the beaded filament protein and supporting its role in human cataract formation.

  3. Data show that BFSP2 and PITX3, hitherto known to cause eye defects only in a dominant fashion, can also present recessively.

  4. The Y-sutural opacity in the lens might be the typical and earliest sign for cataract caused by the BFSP2 mutation. In addition, a myopia susceptibility locus in this region, which might also be associated with the mutation in BFSP2.

  5. Progressive isolated sutural cataract associated with deletion mutation of BFSP2 gene in Chinese pedigree. Physiological importance of beaded filament protein. Role of BFSP2 in human cataract formation.

  6. Progressive phenotype has provided more evidence for the heterogeneity of congenital cataract caused by BFSP2 mutations and for the important role BFSP2 plays in cataract formation.

  7. This is the first reported case of a congenital lamellar cataract phenotype associated with the mutation of Arg339His (P.R339H) in BFSP2.

Mouse (Murine) Beaded Filament Structural Protein 2, Phakinin (BFSP2) interaction partners

  1. CP49 and filensin have been considered robust markers for mouse lens fiber cell differentiation. The data reported here, however, document both proteins in the mouse lens epithelium, but only after 5 weeks of age, when lens epithelial growth and mitotic activity have slowed.

  2. CP49 is involved in a functional synergy critical for regulating lens fiber cell geometry, transparency, and mechanical stiffness.

  3. disruption of the Hsf4 gene leads to cataracts via at least three pathways: down-regulation of gamma-crystallin, particularly gamma S-crystallin; decreased lens beaded filament expression; and loss of post-translational modification of alpha A-crystallin

Zebrafish Beaded Filament Structural Protein 2, Phakinin (BFSP2) interaction partners

  1. Therefore we conclude zebrafish Bfsp2alpha is a functional orthologue conforming more closely to the conventional domain structure of intermediate filament proteins.

BFSP2 profil antigène

Profil protéine

More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.

Gene names and symbols associated with BFSP2

  • beaded filament structural protein 2 (BFSP2) anticorps
  • beaded filament structural protein 2, phakinin (Bfsp2) anticorps
  • beaded filament structural protein 2 (Bfsp2) anticorps
  • beaded filament structural protein 2, phakinin (bfsp2) anticorps
  • AI448593 anticorps
  • Bfsp2 anticorps
  • CP47 anticorps
  • CP49 anticorps
  • CP49INS anticorps
  • CTRCT12 anticorps
  • LIFL-L anticorps
  • LOC100222605 anticorps
  • PHAKOSIN anticorps
  • zgc:103750 anticorps

Protein level used designations for BFSP2

49 kDa cytoskeletal protein , beaded filament protein CP49 , bfps2, Cytoskeletal protein, 49-kD , lens fiber cell beaded filament protein CP 47 , lens fiber cell beaded filament protein CP 49 , lens intermediate filament-like light , phakinin , CP 47 , CP47 , CP49 , beaded filament structural protein 2, phakinin , cytoskeletal protein CP 49 , phakinin-like , DKEYP-73D8.2

GENE ID SPECIES
8419 Homo sapiens
107993 Mus musculus
281645 Bos taurus
396141 Gallus gallus
460708 Pan troglodytes
608938 Canis lupus familiaris
100101576 Oryctolagus cuniculus
100222605 Taeniopygia guttata
100306969 Cavia porcellus
100404357 Callithrix jacchus
100441274 Pongo abelii
100594242 Nomascus leucogenys
501046 Rattus norvegicus
494090 Danio rerio
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