CD63 Molecule Protéines (CD63)

The protein encoded by CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. De plus, nous expédions CD63 Anticorps (636) et CD63 Kits (40) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
CD63 12512 P41731
CD63 967 P08962
CD63 29186 P28648
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Top CD63 Protéines sur anticorps-enligne.fr

Showing 10 out of 22 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,749.58
Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
$5,262.31
Détails
Human Cells Humain His tag 100 μg Connectez-vous pour afficher 14 to 16 Days
$382.80
Détails
Human Cells Rat His tag 100 μg Connectez-vous pour afficher 14 to 16 Days
$437.80
Détails
Escherichia coli (E. coli) Humain His tag,GST tag 100 μg Connectez-vous pour afficher 15 to 18 Days
$800.00
Détails
Human Cells Sanglier Fc Tag 100 μg Connectez-vous pour afficher 14 to 16 Days
$437.80
Détails
Human Cells Cynomolgus His tag 100 μg Connectez-vous pour afficher 14 to 16 Days
$437.80
Détails
Human Cells Souris Fc Tag,ECD 100 μg Connectez-vous pour afficher 14 to 16 Days
$437.80
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher 11 Days
$814.00
Détails
Escherichia coli (E. coli) Souris His tag 50 μg Connectez-vous pour afficher 11 Days
$341.00
Détails

CD63 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine) , ,
, ,
Human , , , ,
, , ,
Rat (Rattus)
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Plus protéines pour CD63 Molecule (CD63) partenaires d'interaction

Mouse (Murine) CD63 Molecule (CD63) interaction partners

  1. In renal proximal tubules, CD63 determines the insertion of OCT2 into the proper membrane domain and mediates transporter regulation by trafficking processes.

  2. TIMP1 signaling via CD63 leads to activation of hepatic stellate cells, which create an environment in the liver that increases its susceptibility to pancreatic tumor cells.

  3. The Muted protein is important for the steady-state level of CD63.

  4. Data show that CD63 is a crucial player in the regulation of the tumor cell-intrinsic metastatic potential by affecting cell plasticity.

  5. These findings identify CD63 as an important component of allergic inflammation.

  6. CD63 serves to bridge between beta1 integrin and VEGFR2 because CD63 silencing disrupted VEGFR2-beta1 integrin complex formation identified using proximity ligation assay

  7. Loss of CD63 is associated impairment of amyloidogenesis and downstream melanosome morphogenesis.

  8. Loss of CD63 has a similar phenotype to loss of P-selectin itself, thus CD63 is an essential cofactor to P-selectin.

  9. CXCR4 can be downregulated on activated B cells by IL-21-induced endocytosis and CD63-mediated endosomal recruitment.

  10. The findings identify palmitoylation-dependent association with the tetraspanin CD63 as the mechanism by which Syt VII is targeted to lysosomes.

  11. CD63, but not RILP, is recruited to the phagosomes in macrophages expressing the dominant negative form of Rab7.

  12. CD63 is recruited to already-budded Weibel-Palade bodies by an AP-3-dependent route

  13. Upon phagocytosis of Cryptococcus neoformans and polystyrene beads, CD63 was recruited selectively to C. neoformans-containing phagosomes in a MyD88-independent acidification-dependent manner

  14. protein region defined by amino acid residues 103-205 for CD63 interacts with amelogenin

  15. CD63 knockout mice show an increased urinary flow, water intake, reduced urine osmolality, and a higher fecal water content.

  16. the activation-induced degranulation of Fas ligand has distinct requirements and involves different mechanisms than those of the granule markers CD63 and CD107a/Lamp-1

Human CD63 Molecule (CD63) interaction partners

  1. Signaling focal contacts via CD63 were identified to facilitate cell adhesion, migration and mediate extracellular matrix-physical cues to modulate hematopoietic stem cells and progenitor cells function.

  2. Human CD63-GFP expression was controlled under the rat Sox2 promoter (Sox2/human CD63-GFP), and it was expressed in undifferentiated fetal brains.

  3. our results identify the CD63-syntenin-1-ALIX complex as a key regulatory component in post-endocytic HPV trafficking.

  4. Exosomal markers CD63 and CD9 are elevated in pancreatic tumor tissues.

  5. CD63 and exosome expression is altered in scleroderma dermal fibroblasts

  6. CD63 is a critical player in LMP1 exosomal trafficking and LMP1-mediated enhancement of exosome production and may play further roles in limiting downstream LMP1 signaling.

  7. TIMP1 signaling via CD63 leads to activation of hepatic stellate cells, which create an environment in the liver that increases its susceptibility to pancreatic tumor cells.

  8. Concentrations of Cd63 were elevated in gingival crevicular fluid of patients with pre-eclampsia.

  9. CD163(+) TAMs in oral premalignant lesions coexpress CD163 and STAT1, suggesting that the TAMs in oral premalignant lesions possess an M1 phenotype in a Th1-dominated micromilieu.

  10. Our findings reveal that elevated levels of TIMP-1 impact on neutrophil homeostasis via signaling through CD63.

  11. These findings indicate that rhTIMP-1 promotes clonogenic expansion and survival in human progenitors via the activation of the CD63/PI3K/pAkt signaling pathway

  12. It was shown that treatment of macrophages with anti-CD63 inhibits CCR5-mediated virus infection in a cell type-specific manner, but that no inhibition of CXCR4-tropic viruses occurs.

  13. TM4SF5 interacted with CD151, and caused the internalization of CD63 from the cell surface.

  14. Diesel exhaust exposure during exercise induces platelet activation as illustrated by a dose-response increase in the release of CD62P and CD63.

  15. Data show that CD63 is a crucial player in the regulation of the tumor cell-intrinsic metastatic potential by affecting cell plasticity.

  16. CD63 tetraspanin is a negative driver of epithelial-to-mesenchymal transition in human melanoma cells.

  17. these results indicated that high glycosylation of CD63 by RPN2 is implicated in clinical outcomes in breast cancer patients

  18. CD9 and CD63 tetraspanins block HIV-1-induced cell-cell fusion at the transition from hemifusion to pore opening.

  19. Collectively, these findings indicate that CD63 may support Env-mediated fusion as well as a late (post-integration) step in the HIV-1 replication cycle.

  20. Data suggest that TIMP1 (tissue inhibitor of metalloproteinase-1) acts as chemoattractant for neural stem cells (NSC); TIMP1 enhances NSC adhesion, migration, and cytoskeletal reorganization; these effects are dependent on CD63/CD29 (integrin beta1).

Profil protéine CD63

Profil protéine

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.

Gene names and symbols associated with CD63 Molecule Protéines (CD63)

  • CD63 antigen (Cd63)
  • CD63 molecule (CD63)
  • Cd63 molecule (Cd63)
  • CD63 molecule (Cd63)
  • C75951 Protéine
  • LAMP-3 Protéine
  • ME491 Protéine
  • MLA1 Protéine
  • OMA81H Protéine
  • TSP29FA Protéine
  • TSPAN30 Protéine

Protein level used designations for CD63 Molecule Protéines (CD63)

melanoma 1 antigen , CD63 antigen , CD63 antigen (melanoma 1 antigen) , granulophysin , lysosomal-associated membrane protein 3 , lysosome-associated membrane glycoprotein 3 , melanoma-associated antigen ME491 , melanoma-associated antigen MLA1 , ocular melanoma-associated antigen , tetraspanin-30 , tspan-30 , ME491/CD63 antigen , mast cell antigen AD1

GENE ID SPECIES
12512 Mus musculus
100155929 Sus scrofa
100051450 Equus caballus
967 Homo sapiens
404156 Bos taurus
493846 Felis catus
100008988 Oryctolagus cuniculus
29186 Rattus norvegicus
474391 Canis lupus familiaris
101114944 Ovis aries
100716198 Cavia porcellus
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