CD63 Molecule Protéines (CD63)

The protein encoded by CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. De plus, nous expédions CD63 Anticorps (646) et CD63 Kits (40) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
CD63 12512 P41731
CD63 967 P08962
CD63 29186 P28648
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Showing 10 out of 22 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
$5,355.45
Détails
Human Cells Humain His tag 100 μg Connectez-vous pour afficher 14 to 16 Days
$382.80
Détails
Human Cells Rat Fc Tag 100 μg Connectez-vous pour afficher 20 to 21 Days
$437.80
Détails
Escherichia coli (E. coli) Humain His tag,GST tag 100 μg Connectez-vous pour afficher 15 to 18 Days
$800.00
Détails
Human Cells Souris Fc Tag,ECD 100 μg Connectez-vous pour afficher 20 to 21 Days
$437.80
Détails
Human Cells Sanglier Fc Tag 100 μg Connectez-vous pour afficher 20 to 21 Days
$437.80
Détails
Human Cells Cynomolgus His tag 100 μg Connectez-vous pour afficher 20 to 21 Days
$437.80
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$814.00
Détails
Escherichia coli (E. coli) Souris His tag 50 μg Connectez-vous pour afficher 11 Days
$341.00
Détails

CD63 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine) , ,
, ,
Human , , , ,
, , ,
Rat (Rattus)
,

Plus protéines pour CD63 Molecule (CD63) partenaires d'interaction

Mouse (Murine) CD63 Molecule (CD63) interaction partners

  1. In renal proximal tubules, CD63 determines the insertion of OCT2 (Montrer SLC22A2 Protéines) into the proper membrane domain and mediates transporter regulation by trafficking processes.

  2. TIMP1 (Montrer TIMP1 Protéines) signaling via CD63 leads to activation of hepatic stellate cells, which create an environment in the liver that increases its susceptibility to pancreatic tumor cells.

  3. The Muted protein (Montrer MUTED Protéines) is important for the steady-state level of CD63.

  4. Data show that CD63 is a crucial player in the regulation of the tumor cell-intrinsic metastatic potential by affecting cell plasticity.

  5. These findings identify CD63 as an important component of allergic inflammation.

  6. CD63 serves to bridge between beta1 integrin and VEGFR2 (Montrer KDR Protéines) because CD63 silencing disrupted VEGFR2 (Montrer KDR Protéines)-beta1 integrin complex formation identified using proximity ligation assay

  7. Loss of CD63 is associated impairment of amyloidogenesis and downstream melanosome morphogenesis.

  8. Loss of CD63 has a similar phenotype to loss of P-selectin (Montrer SELP Protéines) itself, thus CD63 is an essential cofactor to P-selectin (Montrer SELP Protéines).

  9. CXCR4 (Montrer CXCR4 Protéines) can be downregulated on activated B cells by IL-21 (Montrer IL21 Protéines)-induced endocytosis and CD63-mediated endosomal recruitment.

  10. The findings identify palmitoylation-dependent association with the tetraspanin CD63 as the mechanism by which Syt VII (Montrer SYT7 Protéines) is targeted to lysosomes.

Human CD63 Molecule (CD63) interaction partners

  1. Human CD63-GFP expression was controlled under the rat Sox2 (Montrer SOX2 Protéines) promoter (Sox2 (Montrer SOX2 Protéines)/human CD63-GFP), and it was expressed in undifferentiated fetal brains.

  2. our results identify the CD63-syntenin-1 (Montrer SDCBP Protéines)-ALIX (Montrer PDCD6IP Protéines) complex as a key regulatory component in post-endocytic HPV trafficking.

  3. Exosomal markers CD63 and CD9 (Montrer CD9 Protéines) are elevated in pancreatic tumor tissues.

  4. CD63 and exosome expression is altered in scleroderma dermal fibroblasts

  5. CD63 is a critical player in LMP1 (Montrer PDLIM7 Protéines) exosomal trafficking and LMP1 (Montrer PDLIM7 Protéines)-mediated enhancement of exosome production and may play further roles in limiting downstream LMP1 (Montrer PDLIM7 Protéines) signaling.

  6. TIMP1 (Montrer TIMP1 Protéines) signaling via CD63 leads to activation of hepatic stellate cells, which create an environment in the liver that increases its susceptibility to pancreatic tumor cells.

  7. Concentrations of Cd63 were elevated in gingival crevicular fluid of patients with pre-eclampsia.

  8. CD163 (Montrer CD163 Protéines)(+) TAMs in oral premalignant lesions coexpress CD163 (Montrer CD163 Protéines) and STAT1 (Montrer STAT1 Protéines), suggesting that the TAMs in oral premalignant lesions possess an M1 phenotype in a Th1 (Montrer TH1L Protéines)-dominated micromilieu.

  9. Our findings reveal that elevated levels of TIMP-1 (Montrer TIMP1 Protéines) impact on neutrophil homeostasis via signaling through CD63.

  10. These findings indicate that rhTIMP-1 promotes clonogenic expansion and survival in human progenitors via the activation of the CD63/PI3K (Montrer PIK3CA Protéines)/pAkt (Montrer AKT1 Protéines) signaling pathway

Profil protéine CD63

Profil protéine

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.

Gene names and symbols associated with CD63 Molecule Protéines (CD63)

  • CD63 antigen (Cd63)
  • CD63 molecule (CD63)
  • Cd63 molecule (Cd63)
  • CD63 molecule (Cd63)
  • C75951 Protéine
  • LAMP-3 Protéine
  • ME491 Protéine
  • MLA1 Protéine
  • OMA81H Protéine
  • TSP29FA Protéine
  • TSPAN30 Protéine

Protein level used designations for CD63 Molecule Protéines (CD63)

melanoma 1 antigen , CD63 antigen , CD63 antigen (melanoma 1 antigen) , granulophysin , lysosomal-associated membrane protein 3 , lysosome-associated membrane glycoprotein 3 , melanoma-associated antigen ME491 , melanoma-associated antigen MLA1 , ocular melanoma-associated antigen , tetraspanin-30 , tspan-30 , ME491/CD63 antigen , mast cell antigen AD1

GENE ID SPECIES
12512 Mus musculus
100155929 Sus scrofa
100051450 Equus caballus
967 Homo sapiens
404156 Bos taurus
493846 Felis catus
100008988 Oryctolagus cuniculus
29186 Rattus norvegicus
474391 Canis lupus familiaris
101114944 Ovis aries
100716198 Cavia porcellus
Fournisseurs de qualité sélectionnés pour CD63 Protéines (CD63)
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