anti-Calcium Channel, Voltage Dependent, T Type, alpha 1I Subunit (CACNA1I) Anticorps

CACNA1I encodes the pore-forming alpha subunit of a voltage gated calcium channel. De plus, nous expédions CACNA1I Protéines (5) et beaucoup plus de produits pour cette protéine.

Gène	GeneID	UniProt
CACNA1I	239556
CACNA1I	8911	Q9P0X4
CACNA1I	56827	Q9Z0Y8

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Catalogue No.	Reactivité	Hôte	Conjugué	Application	Quantité	Fournisseur	Livraison	Prix	Détails
ABIN2776236	Boeuf (Vache)	Lapin	Inconjugué	WB	100 μL	Connectez-vous pour afficher	2 to 3 Days	$289.00	Détails
ABIN350146	Humain	Lapin	Inconjugué	IHC, WB	100 μL	Connectez-vous pour afficher	7 to 8 Days	$454.67	Détails
ABIN447533	Humain	Lapin	Inconjugué	ICC, IHC (fro), IF, IHC (p), IHC, WB	0.5 mg	Connectez-vous pour afficher	12 to 15 Days	$444.19	Détails
ABIN768756	Roussette (Chauve-souris)	Lapin	Inconjugué	IHC, IHC (p), WB	50 μg	Connectez-vous pour afficher	11 to 14 Days	$727.83	Détails
ABIN396140	Humain	Souris	Inconjugué	ELISA, WB	100 μg	Connectez-vous pour afficher	8 to 11 Days	$461.00	Détails
ABIN3181663	Humain	Lapin	Inconjugué	IHC	100 μL	Connectez-vous pour afficher	16 Days	$181.73	Détails
ABIN5958124	Humain	Lapin	Inconjugué	IHC (p)	200 μL	Connectez-vous pour afficher	12 to 14 Days	$438.90	Détails
ABIN563882	Humain	Souris	Inconjugué	ELISA, WB	100 μg	Connectez-vous pour afficher	11 to 12 Days	$440.00	Détails
ABIN2964792	Humain	Lapin	Inconjugué	WB	10 blots	Connectez-vous pour afficher	7 to 9 Days	$654.50	Détails
ABIN633706	Humain	Lapin	Inconjugué	WB	50 μg	Connectez-vous pour afficher	2 to 3 Days	$473.93	Détails

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Plus d’anticorps contre CACNA1I partenaires d’interaction

Mouse (Murine) Calcium Channel, Voltage Dependent, T Type, alpha 1I Subunit (CACNA1I) interaction partners

Membrane-protein extraction and use of an intracellular protein (Montrer CKAP2 Anticorps)-transport inhibitor showed that GDF-15 (Montrer GDF15 Anticorps) promoted CaV3.1 (Montrer CACNA1G Anticorps) and CaV3.3 alpha-subunit (Montrer POLG Anticorps) expression by trafficking to the membrane.
Extracellular pressure increases [Ca(2 (Montrer CA2 Anticorps)+)]i via Cav3.3, driving a PKC-beta (Montrer PRKCB Anticorps)- IKK (Montrer CHUK Anticorps)- IkB (Montrer NFKBIB Anticorps)-NF-kB pathway that stimulates cancer cell proliferation
using Ca(V)3.3(-/-) mice we found that Ca(V)3.3 channels trigger synaptic plasticity in reticular thalamic neurons
data identify a central role for Ca(V)3.3 channels in the rhythmogenic properties of the sleep-spindle generator and provide a molecular target to elucidate the roles of sleep spindles for brain function and development.

Human Calcium Channel, Voltage Dependent, T Type, alpha 1I Subunit (CACNA1I) interaction partners

analyses suggest that a single copy of Chr22: 39665939G > A CACNA1I has the capacity to disrupt CaV3.3 channel-dependent functions, including rebound bursting in TRN (Montrer TNPO1 Anticorps) neurons, with potential implications for schizophrenia pathophysiology.
low-voltage activation characteristics of CaV3.3 channels
CACNA1I is a risk gene for schizophrenia in the Han Chinese population
human Cav3.1, Cav3.2, and Cav3.3 T-type channels specifically associate with CaM at helix 2 of the gating brake in the I-II linker of the channels.
significant association exists between the CACNA1I gene and schizophrenia in the Uighur Chinese population
CACNA1I variant is associated with differential antiepileptic drug response in childhood absence epilepsy.
CaV3.1 (Montrer CACNA1G Anticorps), CaV3.2 (Montrer CACNA1H Anticorps) and CaV3.3 channels, are best recognized for their negative voltage of activation and inactivation thresholds that allow them to operate near the resting membrane potential of neurons.
Extracellular pressure increases [Ca(2 (Montrer CA2 Anticorps)+)]i via Cav3.3, driving a PKC-beta (Montrer PRKCB Anticorps)- IKK (Montrer CHUK Anticorps)- IkB (Montrer NFKBIB Anticorps)-NF-kB pathway that stimulates cancer cell proliferation
Ethanol primarily affects the CaV3.2 isoform of T-type Ca(2)+ channels, acting through protein kinase C.
Specific contribution of human T-type calcium channel isotypes (alpha(1G (Montrer CACNA1G Anticorps)), alpha(1H) and alpha(1I)) to neuronal excitability.

CACNA1I profil antigène

Profil protéine

This gene encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by this protein is characterized by a slower activation and inactivation compared to other T-type calcium channels. This protein may be involved in calcium signaling in neurons. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with CACNA1I

calcium voltage-gated channel subunit alpha1 I (CACNA1I) anticorps
voltage-dependent T-type calcium channel subunit alpha-1I (LOC100555412) anticorps
calcium channel, voltage-dependent, alpha 1I subunit (Cacna1i) anticorps
calcium voltage-gated channel subunit alpha1 I (Cacna1i) anticorps
calcium channel, voltage-dependent, T type, alpha 1I subunit (cacna1i) anticorps

Ca(v)3.3 anticorps
CACNA1L anticorps
Cav3.3 anticorps
si:ch211-51h13.1 anticorps

Protein level used designations for CACNA1I

alpha1I T-type calcium channel subunit , calcium channel, voltage-dependent, T type, alpha 1I subunit , voltage-dependent T-type calcium channel alpha-1I subunit , voltage-dependent T-type calcium channel subunit alpha-1I-like , low voltage-activated T-type calcium channel alpha-1 subunit (CACNA1I) , low-voltage-activated calcium channel alpha13.3 , calcium channel, voltage-dependent, alpha 1I subunit , voltage-dependent T-type calcium channel subunit alpha-1I , voltage-gated calcium channel subunit alpha Cav3.3 , caVT.3 , hypothetical gene supported by NM_020084 , voltage-dependent calcium channel

GENE ID	SPECIES
282413	Bos taurus
427900	Gallus gallus
458848	Pan troglodytes
708146	Macaca mulatta
100432497	Pongo abelii
100555412	Anolis carolinensis
100587399	Nomascus leucogenys
239556	Mus musculus
8911	Homo sapiens
56827	Rattus norvegicus
566351	Danio rerio
481243	Canis lupus familiaris

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