DnaJ (Hsp40) Homolog, Subfamily B, Member 8 Protéines (DNAJB8)

The protein encoded by DNAJB8 belongs to the DNAJ/HSP40 family of proteins that regulate chaperone activity. De plus, nous expédions DNAJB8 Anticorps (30) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
DNAJB8 165721 Q8NHS0
DNAJB8 56691 Q9QYI7
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Top DNAJB8 Protéines sur anticorps-enligne.fr

Showing 4 out of 5 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Escherichia coli (E. coli) Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
$5,465.26
Détails
Escherichia coli (E. coli) Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
$5,465.26
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails
Escherichia coli (E. coli) Humain His tag 100 μg Connectez-vous pour afficher 15 to 19 Days
$400.00
Détails

DNAJB8 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Mouse (Murine)

Plus protéines pour DnaJ (Hsp40) Homolog, Subfamily B, Member 8 (DNAJB8) partenaires d'interaction

Human DnaJ (Hsp40) Homolog, Subfamily B, Member 8 (DNAJB8) interaction partners

  1. DNAJB8 is a central and versatile player in the protein aggregation and degradation system.DNAJB8 protein keeps Parkin (Montrer PARK2 Protéines) C289G mutant protein in a soluble, degradation-competent form.

  2. Results show that DNAJB8 expression is induced by heat shock stress which increases side population cells and cancer stem-like cells.

  3. Taken together, the results indicate that DNAJB8 is expressed and has role in CRC CSC/CIC and that DNAJB8 is a novel target of CRC CSC/CIC-targeting immunotherapy.

  4. The mechanism of DNAJB6 (Montrer DNAJB6 Protéines) and DNAJB8 is suppression of polyQ protein aggregation by directly binding the polyQ tract.

  5. Cancer stem-like cell (CSC) maintenance and that it offers a candidate for CSC-targeting immunotherapy in renal cell carcinoma

  6. DNAJB6b and DNAJB8 are superior suppressors of aggregation and toxicity of disease-associated polyglutamine proteins.

Mouse (Murine) DnaJ (Hsp40) Homolog, Subfamily B, Member 8 (DNAJB8) interaction partners

  1. Dnajb8 has a role in tumor initiation, side population ratio and sphere formation but it is dispensable for stress responses

  2. findings suggest that DNAJB8 plays a role in Cancer stem-like cell (CSC) maintenance and that it offers a candidate for CSC-targeting immunotherapy in renal cell carcinoma (Montrer MOK Protéines)

Profil protéine DNAJB8

Profil protéine

The protein encoded by this gene belongs to the DNAJ/HSP40 family of proteins that regulate chaperone activity. This family member suppresses aggregation and toxicity of polyglutamine proteins, and the C-terminal tail is essential for this activity. It has been implicated as a cancer-testis antigen and as a cancer stem-like cell antigen involved in renal cell carcinoma.

Gene names and symbols associated with DNAJB8

  • DnaJ heat shock protein family (Hsp40) member B8 (DNAJB8)
  • DnaJ heat shock protein family (Hsp40) member B8 (Dnajb8)
  • 1700016F14Rik Protéine
  • 1700031F10Rik Protéine
  • AI326313 Protéine
  • DJ6 Protéine
  • mDj6 Protéine

Protein level used designations for DNAJB8

dnaJ homolog subfamily B member 8 , DnaJ homolog 6

GENE ID SPECIES
165721 Homo sapiens
56691 Mus musculus
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