Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) Protéines (DPAGT1)

The protein encoded by DPAGT1 is an enzyme that catalyzes the first step in the dolichol-linked oligosaccharide pathway for glycoprotein biosynthesis. De plus, nous expédions Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) Anticorps (53) et Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) Kits (4) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
DPAGT1 13478 P42867
DPAGT1 1798 Q9H3H5
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Top Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) Protéines sur anticorps-enligne.fr

Showing 4 out of 4 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
$5,355.45
Détails
Cellules d'insectes Humain rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Connectez-vous pour afficher 50 to 55 Days
$7,626.01
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails
Escherichia coli (E. coli) Humain Inconjugué   100 μg Connectez-vous pour afficher 11 to 18 Days
$582.75
Détails

DPAGT1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine)

Human , ,
,

Plus protéines pour Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) (DPAGT1) partenaires d'interaction

Human Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) (DPAGT1) interaction partners

  1. present work improves our knowledge of DPAGT1-CDG and provides bases for developing tailored splicing and folding therapies

  2. Studies show that cells coordinate DPAGT1 expression and protein N (Montrer NP Protéines)-glycosylation with canonical Wnt (Montrer WNT2 Protéines) signaling and E-cadherin (Montrer CDH1 Protéines) adhesion via positive and negative feedback mechanisms.

  3. prominent limb-girdle weakness and minimal craniobulbar symptoms who harbour a novel mutation in DPAGT1

  4. Patients with DPAGT1 CMS (Montrer Cd2ap Protéines) share similar clinical features with patients who have CMS (Montrer Cd2ap Protéines) caused by mutations in GFPT1 (Montrer GFPT1 Protéines), another recently identified CMS (Montrer Cd2ap Protéines) subtype.

  5. Results indicate that the clinical spectrum of dolichyl-phosphate alpha-N-acetylglucosaminyltransferase (DPAGT1)-congenital disorders of glycosylation (CDG) is much broader than appreciated so far.

  6. Data suggest that in oral squamous cell carcinoma (OSCC), dysregulation of canonical Wnt (Montrer WNT2 Protéines) signaling and DPAGT1-dependent N-glycosylation induces CTHRC1 (Montrer CTHRC1 Protéines), thereby driving OSCC cell migration and tumor spread.

  7. suggest that the primary pathogenic mechanism of DPAGT1-associated CMS (Montrer Cd2ap Protéines) is reduced levels of AChRs at the endplate region. This finding demonstrates that impairment of the N-linked glycosylation pathway can lead to the development of CMS (Montrer Cd2ap Protéines)

  8. Overexpression of DPAGT1 in human oral squamous cell carcinoma specimens is linked to aberrant activation of canonical Wnt (Montrer WNT2 Protéines) signaling.

  9. We identify DPAGT1 as a gene in which mutations cause a congenital myasthenic syndrome.

  10. Mutations in DPAGT1 gene is associated with Congenital disorder of glycosylation type Ij.

Profil protéine Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) (DPAGT1)

Profil protéine

The protein encoded by this gene is an enzyme that catalyzes the first step in the dolichol-linked oligosaccharide pathway for glycoprotein biosynthesis. This enzyme belongs to the glycosyltransferase family 4. This protein is an integral membrane protein of the endoplasmic reticulum. The congenital disorder of glycosylation type Ij is caused by mutation in the gene encoding this enzyme.

Gene names and symbols associated with DPAGT1

  • dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) (Dpagt1)
  • dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 (Dpagt1)
  • dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 (DPAGT1)
  • ALG7 Protéine
  • AU021132 Protéine
  • CDG-Ij Protéine
  • CDG1J Protéine
  • CMSTA2 Protéine
  • D11S366 Protéine
  • DGPT Protéine
  • DPAGT Protéine
  • DPAGT2 Protéine
  • G1PT Protéine
  • GNPTA Protéine
  • GPT Protéine
  • GTR2 Protéine
  • UAGT Protéine
  • UGAT Protéine

Protein level used designations for DPAGT1

G1PT , N-acetylglucosamine-1-phosphate transferase , UDP-N-acetylglucosamine lysosomal enzyme N-acetylglucosamine phosphotransferase , UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase , dolichyl-phosphate alpha-N-acetylglucosaminephosphotransferase 2 , glcNAc-1-P transferase , GlcNAc-1-P transferase , uridine diphosphate N-acetyl D-glucosamine dolichol phosphate N-acetyl-glucosamine-1 phosphate transferase , UDP-GlcNAc:dolichyl-phosphate N-acetylglucosaminephosphotransferase , dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P tra , dolichyl-phosphate alpha-N-acetylglucosaminyltransferase , GPT , UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase

GENE ID SPECIES
13478 Mus musculus
100689054 Cricetulus griseus
1798 Homo sapiens
537812 Bos taurus
Fournisseurs de qualité sélectionnés pour Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) Protéines (DPAGT1)
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