ELMO/CED-12 Domain Containing 1 Protéines (ELMOD1)

Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family (By similarity). De plus, nous expédions ELMO/CED-12 Domain Containing 1 Anticorps (33) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
Rat ELMOD1 ELMOD1 315670  
ELMOD1 55531 Q8N336
ELMOD1 270162 Q3V1U8
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Top ELMO/CED-12 Domain Containing 1 Protéines sur anticorps-enligne.fr

Showing 6 out of 6 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$547.80
Détails
Levure Orang-Utan His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,876.50
Détails
Levure Boeuf (Vache) His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,876.50
Détails

ELMOD1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, ,
Mouse (Murine)

Plus protéines pour ELMO/CED-12 Domain Containing 1 (ELMOD1) partenaires d'interaction

Human ELMO/CED-12 Domain Containing 1 (ELMOD1) interaction partners

  1. Data suggest that GPR124 (Montrer GPR124 Protéines) promotes cell adhesion via interaction with Elmo1 (Montrer ELMO1 Protéines)-Dock180 (Montrer DOCK1 Protéines) and intersectin 1 (Montrer ITSN1 Protéines)/2; this constitutes a previously unrecognized heteromeric complex that is putatively involved in GPR124 (Montrer GPR124 Protéines)-dependent adhesive/angiogenic responses in vascular endothelial cells. (GPR124 (Montrer GPR124 Protéines) = G-protein coupled receptor 124 (Montrer GPR124 Protéines); Elmo1 (Montrer ELMO1 Protéines) = ELMO domain-containing protein 1; Dock180 (Montrer DOCK1 Protéines) = dedicator of cytokinesis protein 1 (Montrer DOCK1 Protéines) 180 kDa)

  2. The non-opioid sigma-1 receptor (S1R) was identified as a novel effector of GAP activity of ELMOD1-3 proteins as its direct binding to either ELMOD1 or ELMOD2 (Montrer ELMOD2 Protéines) resulted in loss of GAP activity.

Mouse (Murine) ELMO/CED-12 Domain Containing 1 (ELMOD1) interaction partners

  1. Elmod1 has relatively high and selective expression in the brain but as of 2014 has not been well-studied with respect to CNS function or disease associations. It is part of the core brain ignorome. Elmod1 has a high cis (Montrer CISH Protéines)-eQTL (Montrer EQTN Protéines) in hippocampus, hypothalamus, striatum. Hearing sensitivity trait in GeneNetwork.org also maps to the region containing Elmod1.

  2. This finding connecting ELMOD1 deficiencies with stereocilia dysmorphologies establishes a link between the Ras superfamily of small regulatory GTPases and the actin cytoskeleton dynamics of hair cell stereocilia.

Profil protéine ELMO/CED-12 Domain Containing 1 (ELMOD1)

Profil protéine

Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family (By similarity).

Gene names and symbols associated with ELMOD1

  • ELMO domain containing 1 (Elmod1)
  • ELMO domain containing 1 (ELMOD1)
  • ELMO/CED-12 domain containing 1 (Elmod1)
  • 4831417L10 Protéine
  • AI428506 Protéine
  • AI834991 Protéine
  • RGD1564186 Protéine

Protein level used designations for ELMOD1

ELMO domain containing 1 , ELMO domain-containing protein 1

GENE ID SPECIES
315670 Rattus norvegicus
55531 Homo sapiens
270162 Mus musculus
768233 Bos taurus
100174164 Pongo abelii
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