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ENGASE encodes a cytosolic enzyme which catalyzes the hydrolysis of peptides and proteins with mannose modifications to produce free oligosaccharides. De plus, nous expédions ENGASE Anticorps (11) et ENGASE Protéines (3) et beaucoup plus de produits pour cette protéine.
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In patients with autosomal dominant polycystic kidney disease, urinary NAGase was correlated with urinary ET-1 (Montrer EDN1 Kits ELISA) which was inversely associated with eGFR (Montrer EGFR Kits ELISA) and positively correlated with total kidney volume.
Serological N-acetyl-glucosaminidase (Montrer NAGLU Kits ELISA), telomere length, and the UCP2 (Montrer UCP2 Kits ELISA)-886G>A variant are independent risk factors for type 2 diabetes.
As the generation of the bulk of fOS is unaffected by co-down regulation of Ngly1p and Engase1p, alternative quantitatively important mechanisms must underlie the liberation of these fOS from either LLO or glycoproteins during protein N-glycosylation.
O-GlcNAcase (Montrer MGEA5 Kits ELISA) expression is increased in erythrocytes from both individuals with pre-diabetes and individuals with less well-controlled diabetes.
involved in processing of free oligosaccharides in the cytosol; identification of the gene encoding human cytosolic ENGase
endo-beta-n-acetylglucosaminidase present in the synovial fluid of rheumatoid arthritis patients, may contribute to the depletion of glycosaminoglycans from cartilage allowing the invasion of synovial cells
identification of O-GlcNAcase (Montrer MGEA5 Kits ELISA) as a caspase-3 (Montrer CASP3 Kits ELISA) substrate with a novel caspase-3 (Montrer CASP3 Kits ELISA) cleavage site and provide insight about O-GlcNAcase (Montrer MGEA5 Kits ELISA) regulation during apoptosis.
These observations strongly suggest that the Ngly1 (Montrer NGLY1 Kits ELISA)- or Ngly1 (Montrer NGLY1 Kits ELISA)/Engase-deficient mice could serve as a valuable animal model for studies related to the pathogenesis of the NGLY1 (Montrer NGLY1 Kits ELISA)-deficiency, and that cytoplasmic ENGase represents one of the potential therapeutic targets for this genetic disorder.
ENGase efficiently hydrolyzes phosphorylated oligosaccharides that are larger than Man4GlcNAc2-P, generating GlcNAc-1-P and neutral Gn1 (Montrer GYG1 Kits ELISA)-type free oligosaccharides.
This gene encodes a cytosolic enzyme which catalyzes the hydrolysis of peptides and proteins with mannose modifications to produce free oligosaccharides.
, Di-N-acetylchitobiosyl beta-N-acetylglucosaminidase
, Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
, Cytosolic endo-beta-N-acetylglucosaminidase