Enhancer of MRNA Decapping 3 Homolog (S. Cerevisiae) Protéines (EDC3)

EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM, Mar 2008].. De plus, nous expédions EDC3 Anticorps (55) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
Rat EDC3 EDC3 315708  
EDC3 80153 Q96F86
EDC3 353190 Q8K2D3
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Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 60 Days
$8,498.50
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Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 60 Days
$8,498.50
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HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher 10 to 12 Days
$554.07
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Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
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Levure Schizosaccharomyces pombe His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$3,274.33
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EDC3 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, ,
Mouse (Murine)

Plus protéines pour Enhancer of MRNA Decapping 3 Homolog (S. Cerevisiae) (EDC3) partenaires d'interaction

Fruit Fly (Drosophila melanogaster) Enhancer of MRNA Decapping 3 Homolog (S. Cerevisiae) (EDC3) interaction partners

  1. The modular architecture enables enhancer of decapping 3 (EDC3) to interact with multiple components of the decapping (Montrer ACE Protéines) machi (Montrer DCP2 Protéines)nery, inclu (Montrer DDX6 Protéines)ding DCP1, DCP2, and Me31B.

  2. Tral (Montrer LSM14A Protéines) and EDC3 specifically interact with the decapping activator DCP1 (Montrer ACE Protéines) and the DEAD-box helicase Me31B (Montrer DDX6 Protéines), in Drosophila cells.

Human Enhancer of MRNA Decapping 3 Homolog (S. Cerevisiae) (EDC3) interaction partners

  1. In vitro decapping assays showed that altered EDC3 is unable to enhance DCP2 (Montrer DCP2 Protéines) decapping at low concentrations and even inhibits DCP2 (Montrer DCP2 Protéines) decapping at high concentration.

  2. The modular architecture enables EDC3 to interact with multiple components of the decapping machinery, including DCP1 (Montrer ACE Protéines), DCP2 (Montrer DCP2 Protéines), and Me31B (Montrer DDX6 Protéines).

  3. The dimerization interface of Edc3 is highly conserved in eukaryotes despite the overall low sequence homology across species; structure-based site-directed mutagenesis revealed dimerization is required for efficient RNA binding, P-body formation

  4. Structural basis for the mutually exclusive anchoring of P body components EDC3 and Tral (Montrer LSM14A Protéines) to the DEAD box protein (Montrer INTS6 Protéines) DDX6/Me31B (Montrer DDX6 Protéines).

Mouse (Murine) Enhancer of MRNA Decapping 3 Homolog (S. Cerevisiae) (EDC3) interaction partners

  1. Induction of 14-3-3 (Montrer YWHAQ Protéines) binding to EDC3 causes morphological changes in processing body structures, inhibition of microRNA-mediated mRNA post-transcriptional regulation, and alterations in the protein- protein interactions of EDC3.

Profil protéine EDC3

Profil protéine

EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005

Gene names and symbols associated with EDC3

  • enhancer of mRNA decapping 3 (Edc3)
  • Enhancer of decapping 3 (Edc3)
  • enhancer of mRNA decapping 3 S homeolog (edc3.S)
  • enhancer of mRNA decapping 3 (EDC3)
  • enhancer of mRNA decapping 3 homolog (S. cerevisiae) (edc3)
  • AA517853 Protéine
  • CG6311 Protéine
  • DmEDC3 Protéine
  • Dmel\\CG6311 Protéine
  • EDC3 Protéine
  • im:7151288 Protéine
  • lsm16 Protéine
  • RGD1306898 Protéine
  • wu:fb82d07 Protéine
  • Yjdc Protéine
  • YJEFN2 Protéine
  • zgc:112006 Protéine

Protein level used designations for EDC3

LSM16 homolog (EDC3, S. cerevisiae) , CG6311-PB , Edc3-PB , enhancer of decapping 3 , enhancer of decapping-3 , enhancer of mRNA decapping 3 homolog , enhancer of mRNA-decapping protein 3 , yjeF domain-containing protein 1 , hYjeF_N2 , hYjeF_N2-15q23 , yjeF N-terminal domain-containing protein 2 , yjeF domain containing , yjeF_N2 , LSM16 protein homolog

GENE ID SPECIES
315708 Rattus norvegicus
39957 Drosophila melanogaster
495065 Xenopus laevis
100171859 Pongo abelii
80153 Homo sapiens
353190 Mus musculus
415294 Gallus gallus
504054 Danio rerio
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