Profil protéine

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with F-Box Protein 32 Protéines (FBXO32)

• F-box protein 32 (fbxo32) anticorps
• F-box protein 32 (FBXO32) anticorps
• F-box protein 32 (Fbxo32) anticorps

• 4833442G10Rik anticorps
• AI430017 anticorps
• Atrogin1 anticorps
• Fbx32 anticorps
• Gm20361 anticorps
• Afficher tous les alias de synonymes
• MAFbx anticorps
• MGC56479 anticorps
• zgc:56479 anticorps

Protein level used designations for F-Box Protein 32 Protéines (FBXO32)

F-box only protein 32 , atrogin-1 , F-box protein 32 , F-box only protein 32-like , atrogin 1 , muscle atrophy F-box protein , atrophy gene 1