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Members of the F-box protein family, such as FBXL14, are characterized by an approximately 40-amino acid F-box motif. De plus, nous expédions FBXL14 Kits (13) et FBXL14 Protéines (4) et beaucoup plus de produits pour cette protéine.
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results suggest that SCF(FBXL14) promotes neuronal differentiation by targeting HES1 for ubiquitin-dependent proteolysis and that the C-terminal WRPW motif in HES1 is required for this process
Data show that Twist1 small interfering RNA prevents hypoxia-induced Fbxl14 down-regulation and SNAIL1 stabilization.
USP13 and FBXL14 play opposing roles in the regulation of glioma stem cells (GSCs) through reversible ubiquitination of c-Myc.
Concludes that patterning of ppa mRNA could reflect a constraint on ppa function that is not common among F-box genes.
The F box protein partner of paired (Ppa) mediates CenH3(CID) stability in Drosophila. Ppa depletion results in increased CenH3(CID) levels. Ppa physically interacts with CenH3(CID) through the CATD(CID) that mediates Ppa-dependent CenH3(CID) stability.
Members of the F-box protein family, such as FBXL14, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1\; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004
F-box/LRR-repeat protein 14
, F-box leucine-rich repeat protein 13
, partner of paired b
, partner of paired a