F-Box and Leucine-Rich Repeat Protein 2 Protéines (FBXL2)

FBXL2 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. De plus, nous expédions FBXL2 Anticorps (52) et FBXL2 Kits (12) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
FBXL2 25827 Q9UKC9
FBXL2 72179 Q8BH16
Rat FBXL2 FBXL2 363156  
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Showing 6 out of 6 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Escherichia coli (E. coli) Humain His-SUMO Tag 100 μg Connectez-vous pour afficher 11 Days
$411.40
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$814.00
Détails
Levure Boeuf (Vache) His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$3,179.00
Détails

FBXL2 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , , ,
, , ,
Mouse (Murine)

Plus protéines pour F-Box and Leucine-Rich Repeat Protein 2 (FBXL2) partenaires d'interaction

Human F-Box and Leucine-Rich Repeat Protein 2 (FBXL2) interaction partners

  1. PTEN counteracts FBXL2 to promote IP3R3 (Montrer ITPR3 Protéines)- and Ca(2 (Montrer CA2 Protéines)+)-mediated apoptosis limiting tumour growth

  2. these results uncover a previous unknown network involving FBXL2 and FoxM1 (Montrer FOXM1 Protéines) in the regulation of gastric cancer growth.

  3. FBXL2 recognizes Trp-73 within NALP3 for interaction and targets Lys-689 within NALP3 for ubiquitin ligation and degradation.

  4. FBXL2 mediates the ubiquitylation and degradation of p85beta on cell membranes.

  5. These results suggested that the involvement of the reduction of FBL2 level is related to AD progression.

  6. FBXL2 is indispensible regulator of mitosis that serves as a tumor suppressor

  7. FBXL2 targets cyclin D2 (Montrer CCND2 Protéines) for ubiquitination and degradation to inhibit leukemic cell proliferation.

  8. FBL2 is a novel and dual regulator of amyloid precursor protein (APP (Montrer APP Protéines)) metabolism through FBL2-dependent ubiquitination of APP (Montrer APP Protéines).

Mouse (Murine) F-Box and Leucine-Rich Repeat Protein 2 (FBXL2) interaction partners

  1. FBXL2 mediates Aurora B (Montrer AURKC Protéines) ubiquitination and degradation within the midbody, which is sufficient to induce mitotic arrest and apoptosis.

  2. FBXL2 is a ubiquitin E3 ligase subunit that triggers mitotic arrest.

Profil protéine FBXL2

Profil protéine

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with FBXL2

  • F-box and leucine rich repeat protein 2 (FBXL2)
  • F-box and leucine-rich repeat protein 2 (Fbxl2)
  • F-box and leucine-rich repeat protein 2 (fbxl2)
  • F-box and leucine rich repeat protein 2 (Fbxl2)
  • 2810423A21Rik Protéine
  • FBL2 Protéine
  • Fbl3 Protéine
  • fbxl20 Protéine
  • RGD1562243 Protéine
  • sb:cb783 Protéine
  • zgc:73374 Protéine

Protein level used designations for FBXL2

F-box protein FBL2/FBL3 , F-box protein containing leucine-rich repeats , F-box/LRR-repeat protein 2 , F-box and leucine-rich repeat protein 20

GENE ID SPECIES
25827 Homo sapiens
72179 Mus musculus
616212 Bos taurus
363156 Rattus norvegicus
378737 Danio rerio
485573 Canis lupus familiaris
100719708 Cavia porcellus
420722 Gallus gallus
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